Bleeding Complications in JAK2‐Variant Essential Thrombocythemia: A Revisit in 2025
ABSTRACT Essential thrombocythemia (ET) is a myeloproliferative neoplasm characterised by sustained thrombocytosis. Paradoxically, bleeding complications remain an under‐recognised clinical challenge. Compared with CALR‐mutated patients, those harbouring the JAK2‐V617F variant appear more prone to haemorrhage.
Gerard Gurumurthy+4 more
wiley +1 more source
Von Willebrand Factor Collagen-Binding Activity and Von Willebrand Factor-Mediated Platelet Adhesion in Patients with Coronary Artery Disease. [PDF]
Gabbasov Z+8 more
europepmc +1 more source
IL-1 and related cytokines enhance thrombin-stimulated PGI2 production in cultured endothelial cells without affecting thrombin-stimulated von Willebrand factor secretion or platelet-activating factor biosynthesis. [PDF]
George B. Zavoico+3 more
openalex +1 more source
Hemophilia and von Willebrand disease
openaire +2 more sources
ABSTRACT Objectives The present study investigated the effects of thrombosis, hemorrhagic events, disease progression, and secondary malignancies on patient survival after the diagnosis of essential thrombocythemia (ET). Methods We analyzed data from 1152 patients enrolled in the JSH‐MPN‐18 study using time‐dependent Cox regression and multistate ...
Yoshinori Hashimoto+24 more
wiley +1 more source
Overall leukocyte levels link risk factors to Von Willebrand factor and Neutrophil Extracellular Traps in stroke thrombi: a Structural Equation Modeling analysis. [PDF]
Shi L+13 more
europepmc +1 more source
Absence of a Bleeding Tendency in Severe Acquired Von Willebrand’s Disease: The Role of Platelet Von Willebrand Factor in Maintaining Normal Hemostasis [PDF]
Jeanne Drouin+7 more
openalex +1 more source
Abstract Post‐COVID‐19 condition (PCC), also known as long COVID, is a complex multiple organ system condition that can develop and persist for months after acute COVID‐19. PCC encompasses a wide range of symptoms, resulting in heterogeneous clinical manifestations. These manifestations likely arise from diverse underlying pathophysiological mechanisms,
Larissa E Vlaming‐van Eijk+5 more
wiley +1 more source
N-ACETYLCYSTEINE REDUCES VON WILLEBRAND FACTOR MULTIMER SIZE AND IMPROVES RENAL MICROVASCULAR BLOOD FLOW IN RATS AFTER SEVERE TRAUMA. [PDF]
St John A+10 more
europepmc +1 more source
Glanzmann thrombasthenia: deficient binding of von Willebrand factor to thrombin-stimulated platelets. [PDF]
Zaverio M. Ruggeri+2 more
openalex +1 more source