Results 51 to 60 of about 214,027 (378)
Clearance of von Willebrand factor [PDF]
Thrombosis and Haemostasis, 2008 SummaryThe life cycle of von Willebrand factor (VWF) comprises a number of distinct steps, ranging from the controlled expression of theVWF gene in endothelial cells and megakaryocytes to the removal of VWF from the circulation. The various aspects of VWF clearance have been the objects of intense research in the last few years, stimulated by ...
Cécile V. Denis +3 more
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The role of von Willebrand factor in determining the risk of ischemic stroke in Hawler city: a case-control study [PDF]
Zanco Journal of Medical Sciences, 2018 Background and objective: Ischemic stroke is classically characterized as a neurological deficit attributed to an acute focal injury of the central nervous system by a vascular cause, it occurs as a result of obstruction by a blood clot (thrombus) or ...
Sazgar Anwar Hameed, Salar Adnan Ahmed
doaj +1 more source
Reciprocal interactions between tumor and endothelial cells: Effects of selective vasopressin V2 receptor peptide agonists [PDF]
, 2014 Recent experimental evidence suggested that the synthetic peptide desmopressin (DDAVP) interferes tumor angiogenesis by inducing the formation of angiostatin.
Alonso, Daniel Fernando, Garona, Juan
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Clearance of von Willebrand factor [PDF]
Journal of Thrombosis and Haemostasis, 2013 Quantitative deficiencies in von Willebrand factor (VWF) are associated with abnormal hemostasis that can manifest in bleeding or thrombotic complications. Consequently, many studies have endeavored to elucidate the mechanisms underlying the regulation of VWF plasma levels. This review focuses on the role of VWF clearance pathways.
Caterina Casari +4 more
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ADAMTS proteinases: a multi-domain, multi-functional family with roles in extracellular matrix turnover and arthritis [PDF]
, 2005 Members of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family are known to influence development, angiogenesis, coagulation and progression of arthritis.
Jones, GC, Riley, GP
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Ibrutinib effect in acquired von Willebrand syndrome secondary to Waldenström macroglobulinemia
Therapeutic Advances in Hematology, 2021 The pathological increase of clonal IgM in Waldenström macroglobulinemia can be associated with acquired von Willebrand syndrome and can be a major risk of bleeding symptoms in this subgroup of patients with Waldenström macroglobulinemia.
María Poza +6 more
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Flow-induced elongation of von Willebrand factor precedes tension-dependent activation
Nature Communications, 2017 Von Willebrand factor, an ultralarge concatemeric blood protein, must bind to platelet GPIbα during bleeding to mediate hemostasis, but not in the normal circulation to avoid thrombosis.
Hongxia Fu +5 more
semanticscholar +1 more source
Zebrafish von Willebrand factor [PDF]
Blood Cells, Molecules, and Diseases, 2010 von Willebrand factor (vWF) is a large protein involved in primary hemostasis. A dysfunction in this protein or an insufficient production of the protein leads to improper platelet adhesion/aggregation, resulting in a bleeding phenotype known as von Willebrand disease (vWD).
Vrinda Kulkarni +4 more
openaire +3 more sources
High Glucose, But Not Testosterone, Increases Platelet Aggregation Mediated by Endothelial Cells [PDF]
, 2015 Endothelial cells inhibit platelet aggregation by releasing thromboregulators, such as prostacyclin and nitric oxide. Male subject is a traditional risk factor for cardiovascular diseases.
Aswin, S. (Soedjono) +3 more
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Научно-практическая ревматология, 2004 Objective. To determine the importance of von Willebrand factor antigen as marker of endotheliae damage at the patients with systemic lupus erythematosus (SLE). Material and methods. 30 women from authentic SLE by criteria ACR, in the age of 20-45 years,
M E Zapryagaeva, E S Mach, A A Baranov
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