Results 81 to 90 of about 328,885 (284)
von Willebrand factor biosynthesis, secretion, and clearance: connecting the far ends.
Blood, 2015 To understand the placement of a certain protein in a physiological system and the pathogenesis of related disorders, it is not only of interest to determine its function but also important to describe the sequential steps in its life cycle, from ...
P. Lenting, O. Christophe, C. Denis
semanticscholar +1 more source
Characterization of the defect of the factor VIII/von Willebrand factor protein in von Willebrand's disease [PDF]
Blood, 1982 Abstract The factor VIII/von Willebrand factor (f.VIII/vWf) protein was purified from the plasma of a patient with von Willebrand's disease (vWd). The patient had all of the classic laboratory findings of vWd except for the ristocetin-induced platelet aggregation of his own platelet-rich plasma.
Mary C. Cregger +2 more
openaire +3 more sources
Endothelial cell synthesis of von Willebrand antigen II, von Willebrand factor, and von Willebrand factor/von Willebrand antigen II complex. [PDF]
Journal of Clinical Investigation, 1985 von Willebrand antigen II (vW AgII) and von Willebrand factor (vWf) are immunochemically distinct proteins that are deficient in the plasma and platelets of patients with severe von Willebrand's disease. Normal human umbilical vein endothelial cells were cultured in the presence of [35S]methionine.
E G Levin +2 more
openaire +3 more sources
ADAMTS‐13 and von Willebrand factor predict venous thromboembolism in patients with cancer
Journal of Thrombosis and Haemostasis, 2016 Essentials Cancer patients are at high risk of venous thromboembolism (VTE). In this study, cases and controls were cancer patients who did or did not develop VTE.
Marion Pépin +9 more
semanticscholar +1 more source
Conformational dynamics of charged polymers interacting with charged nanoparticles [PDF]
arXiv, 2018 The transition from globular to elongated states of biopolymers in shear flow occurs at a distinct critical shear rate, $\dot{\gamma }^{*}$. The magnitude of $\dot{\gamma }^{*}$ depends on the internal potential and the polymer length. For example, the critical shear is much larger for von Willebrand Factor (vWF) compared to DNA.
arxiv
ADAMTS13 and von Willebrand factor in thrombotic thrombocytopenic purpura.
Annual Review of Medicine, 2015 Pathogenesis of thrombotic thrombocytopenic purpura (TTP) was a mystery for over half a century until the discovery of ADAMTS13. ADAMTS13 is primarily synthesized in the liver, and its main function is to cleave von Willebrand factor (VWF) anchored on ...
X. Zheng
semanticscholar +1 more source
Folding of Pig Gastric Mucin Non-glycosylated Domains: A Discrete Molecular Dynamics Study [PDF]
arXiv, 2009 Mucin glycoprotein consist of tandem repeating glycosylated regions flanked by non-repetitive protein domains with little glycosylation. These non-repetitive domains are involved in the pH dependent gelation of gastric mucin, which is essential to protecting the stomach from autodigestion.
arxiv
Blood, 2015 This phase 3 trial evaluated the safety and hemostatic efficacy of a recombinant von Willebrand factor (rVWF) for treatment of bleeds in severe von Willebrand disease (VWD).
J. Gill +11 more
semanticscholar +1 more source
Journal of Thrombosis and Haemostasis, 2015 I . BOD O,* J . E IKENBOOM,† R . MONTGOMERY ,‡ J . PATZKE ,§ R . SCHNEPPENHE IM ¶ and J . D I PAOLA ,** ON BEHALF OF THE SUBCOMMITTEE ON VON WILLEBRAND FACTOR *Department of Hematology and Stem Cell Transplantation, St L aszl o Hospital, Budapest ...
Imre Bodó +5 more
semanticscholar +1 more source
Multiple Sclerosis Diagnosed in a Woman With Von-Willebrand Disease: A Case Report
Caspian Journal of Neurological Sciences, 2022 Background: Von-Willebrand Disease (VWD) is the most common inherited bleeding disorder with an autosomal inheritance pattern. Multiple Sclerosis (MS) is a neurological disease, causing neurodegeneration and demyelination of the central nervous system ...
Mohsen Farjoud Kouhanjani +2 more
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