Results 101 to 110 of about 47,572 (272)

Haemorrhagic cystitis following the administration of voriconazole in the treatment of central nervous system aspergillosis: a case report

Journal of International Medical Research, 2020
Central nervous system aspergillosis (CNS-A) is a rare and fatal fungal infection. Voriconazole is the recommended treatment for CNS-A. The therapeutic effect of voriconazole is good, but its use is limited due to adverse reactions.
Zhaohao Zeng, Hong Luo, Kunyu Huang, Lianfang Xue, Hui Liu, Xiaoting Li, Lu Wang, Haimei Cen, Wei Bi, Yu Zhang   +9 more
doaj   +1 more source

18‐FDG PET in the Evaluation of Therapeutic Response of Necrotizing Otitis Externa

The Laryngoscope, EarlyView.
PET performed well in assessing the therapeutic response of NEO, with excellent sensitivity but low specificity of visual analysis. A complementary quantitative analysis was useful to distinguish between satisfactory and insufficient partial responses. ABSTRACT Objective The duration of antibiotic treatment for necrotizing otitis externa (NEO) and the ...
Lucie Lécolier, Philippine Toulemonde, Damien Huglo, Clio Baillet, Pauline Thill, Gauthier Delaby   +5 more
wiley   +1 more source

Effect of voriconazole on Candida tropicalis biofilms: Relation with ERG genes expression [PDF]

, 2016
Candida tropicalis has emerged as the third most prevalent fungal pathogens and its ability to form biofilms has been considered one of the most important virulence factors, since biofilms represent high tolerance to antifungal agents.
C Luca De, CA Kumamoto, DW Williams, DW Williams, E Fonseca, EM Kojic, FC Bizerra, GS Baillie, KJ Livak, LJ Douglas, M Negri, M Negri, MA Al-Fattani, Mariana Henriques, NN Mishra, P Eggimann, P Muñoz, P Vandeputte, PK Mukherjee, RJ Kothavade, S Silva, S Silva, S Silva, S Silva, S Silva, SK Fridkin, SP Hawser, Sónia Silva, T Fernandes, Tânia Fernandes   +29 more
core   +1 more source

Voriconazole-Associated Phototoxicity

Dermatology Online Journal, 2011
Voriconazole is an extended-spectrum triazole antifungal approved for treatment of invasive fungal infections. The drug has been associated with phototoxicity, presenting as photodistributed eruptions such as macular erythema or pseudoporphyria. We describe a 59-year-old man with acute myeloid leukemia, status-post matched unrelated donor stem cell ...
Riahi, Ryan R, Cohen, Philip R
openaire   +4 more sources

Tolerability of oral itraconazole and voriconazole for the treatment of chronic pulmonary aspergillosis: A systematic review and meta-analysis.

PLoS ONE, 2020
BackgroundChronic pulmonary aspergillosis (CPA) requires prolonged treatment with itraconazole or voriconazole. However, adverse events (AEs) are common with the use of these agents, with the need to discontinue the offending drug in a significant ...
Ronald Olum, Joseph Baruch Baluku, Andrew Kazibwe, Laura Russell, Felix Bongomin   +4 more
doaj   +1 more source

Fungal‐Driven Airways Dis‐Immunity From Asthma to Allergic Bronchopulmonary Aspergillosis: Dissecting Similarities and Differences

Allergy, EarlyView.
ABSTRACT Severe asthma and allergic bronchopulmonary aspergillosis (ABPA) do not rarely coexist and share several similarities in terms of pathobiological background, together with overlapping clinical manifestations, misleading the correct diagnosis. Within that scenario, severe asthma with fungal sensitization (SAFS) further complicates the correct ...
Marco Caminati, Isabella Annesi‐Maesano, Wojciech Feleszko, Giuseppe Guida, Christer Janson, Shadi Hägg, Andrei Malinovschi, Luciana Tanno, Joana Vitte, Francesca Ambrosani, Matteo Maule   +10 more
wiley   +1 more source

Impact of glucuronide interferences on therapeutic drug monitoring of posaconazole by tandem mass spectrometry [PDF]

, 2010
Background: Posaconazole is a novel antifungal drug for oral application intended especially for therapy of invasive mycoses. Due to variable gastrointestinal absorption, adverse side effects, and suspected drug-drug interactions, therapeutic drug ...
Burghardt, Stephan, Krueger, Ralf, Lackner, Karl J., Vogelsberger, Rita, Vogeser, Michael   +4 more
core   +1 more source

Antimicrobial prescribing guidelines for horses in Australia

Australian Veterinary Journal, EarlyView.
The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt, K Thomas, S Page, J Norris, G Browning, C El Hage, A Stewart, J Gilkerson, G Muscatello, D Verwilghen, G van Galen, J Bauquier, R Cuming, B Reynolds, C Whittaker, E Wilkes, J Clulow, C Burden, L Begg   +18 more
wiley   +1 more source

Institutional Experience with Voriconazole Compared with Liposomal Amphotericin B as Empiric Therapy for Febrile Neutropenia [PDF]

, 2007
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90034/1/phco.27.7.970 ...
Boogaerts M, Cagnoni PJ, Curtis D Collins, Daryl D DePestel, Donowitz GR, Emily R Mackler, Harry P Erba, Hoban DJ, Jorgensen KJ, Kappe R, Kathleen Welch, Klastersky J, Nadine Shehab   +12 more
core   +1 more source

A 23 bp cyp51A Promoter Deletion Associated With Voriconazole Resistance in Clinical and Environmental Isolates of Neocosmospora keratoplastica

Frontiers in Microbiology, 2020
In the fungal pathogen Aspergillus fumigatus, resistance to azole antifungals is often linked to mutations in CYP51A, a gene that encodes the azole antifungal drug target lanosterol 14α-demethylase.
Jasper Elvin James, Erwin Lamping, Jacinta Santhanam, Trudy Jane Milne, Mohd Fuat Abd Razak, Latiffah Zakaria, Richard David Cannon   +6 more
doaj   +1 more source