Therapeutic Drug Monitoring of Sputum Voriconazole in Pulmonary Aspergillosis
Pharmaceutics, 2022 Voriconazole is one of the most used antifungal azoles against pulmonary aspergillosis. Therapeutic drug monitoring (TDM) of the voriconazole concentration in plasma is recommended in clinical practice guidelines to prevent treatment failure and toxicity.
Sacha Sarfati +7 more
doaj +1 more source
Analysis of imidazoles and triazoles in biological samples after MicroExtraction by packed sorbent [PDF]
, 2017 This paper reports the MEPS-HPLC-DAD method for the simultaneous determination of 12 azole drugs (bifonazole, butoconazole, clotrimazole, econazole, itraconazole, ketoconazole, miconazole, posaconazole, ravuconazole, terconazole, tioconazole and ...
Bellagamba, Giuseppe +9 more
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Bloodstream yeast infections: a 15-month survey [PDF]
, 2009 A 15-month survey of 412 bloodstream yeast isolates from 54 Belgian hospitals was undertaken. Candida albicans was the most common species (47.3%) followed by C. glabrata (25.7%), C. parapsilosis (8.0%), C. tropicalis (6.8%) and Saccharomyces cerevisiae (
Detandt, M +3 more
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Pharmacogenomic testing and its future in community pharmacy [PDF]
, 2020 Although it is common to see pharmacogenomic testing used North America and Australia, it is not yet part of practice in the UK. With the promise of genomic screening becoming part of the NHS, pharmacists must equip themselves with a knowledge of how the
Wright, David, Youssef, Essra
core +1 more source
Clinical and Translational Science, 2021 Voriconazole is the mainstay for the treatment of invasive fungal infections in patients who underwent a kidney transplant. Variant CYP2C19 alleles, hepatic function, and concomitant medications are directly involved in the metabolism of voriconazole ...
Yi‐Chang Zhao +9 more
doaj +1 more source
Intracranial fusarium fungal abscess in an immunocompetent patient: case report and review of the literature. [PDF]
, 2014 Introduction Fusarium spp is an omnipresent fungal species that may lead to fatal infections in immunocompromised populations. Spontaneous intracranial infection by Fusarium spp in immunocompetent individuals is exceedingly rare.
Cadden, Joseph +6 more
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Medication Complications in Extracorporeal Membrane Oxygenation. [PDF]
, 2017 The need for extracorporeal membrane oxygenation (ECMO) therapy is a marker of disease severity for which multiple medications are required. The therapy causes physiologic changes that impact drug pharmacokinetics.
Aebi +99 more
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Biofilm-forming capability of highly virulent, multidrug-resistant Candida auris [PDF]
, 2017 The emerging multidrug-resistant yeast pathogen Candida auris has attracted considerable attention as a source of healthcare–associated infections. We report that this highly virulent yeast has the capacity to form antifungal resistant biofilms sensitive
Borman, Andrew +6 more
core +4 more sources
Drug reservoir function of voriconazole impregnated human amniotic membrane: An in vitro study
Indian Journal of Ophthalmology, 2021 Purpose: Earlier our group has demonstrated the drug reservoir function of the human amniotic membrane (HAM) using stable moxifloxacin and fortified cefazolin ophthalmic formulations and found it as a suitable tool to deliver drugs for an extended ...
Manali Hazarika +2 more
doaj +1 more source
Invasive pulmonary aspergillosis complicating COVID-19 in the ICU - A case report. [PDF]
, 2021 It is not yet known, if critically ill COVID-19 patients are prone to fungal infections. We report a 69-year-old patient without typical risk factors for invasive pulmonary aspergillosis (IPA), who developed IPA two weeks after onset of symptoms.
Eller, Philipp +5 more
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