Results 21 to 30 of about 27,626 (220)

Impact of Inflammation on Voriconazole Exposure in Critically ill Patients Affected by Probable COVID-19-Associated Pulmonary Aspergillosis

open access: yesAntibiotics, 2023
(1) Background: To explore the impact of the degree of inflammation on voriconazole exposure in critically ill patients affected by COVID-associated pulmonary aspergillosis (CAPA); (2) Methods: Critically ill patients receiving TDM-guided voriconazole ...
Milo Gatti   +6 more
doaj   +1 more source

The pharmacokinetics of voriconazole [PDF]

open access: yesBritish Journal of Clinical Pharmacology, 2003
Voriconazole (Vfend® Pfizer Global Research and Development, Sandwich, Kent, UK) is a broad-spectrum antifungal triazole that is structurally related to fluconazole. As with all triazole antifungal agents, voriconazole works principally by inhibition of cytochrome P450 14-α-demethylase (P450 14DM) [1, 2].
openaire   +3 more sources

Voriconazole-induced periostitis

open access: yesReumatismo, 2021
Voriconazole is a fluorinated drug from the triazole group that is widely used in the prophylaxis and treatment of fungal infections in immunosuppressed patients. Chronic use of this medication can generate, as an adverse effect, a multifocal, asymmetric, diffuse and nodular periosteal reaction, associated with severe and disabling skeletal pain and ...
D.C. Fernández Ávila   +7 more
openaire   +4 more sources

Voriconazole

open access: yesDrugs in R & D, 1999
Item does not contain ...
Verweij, P.E.   +2 more
openaire   +4 more sources

Relationship between voriconazole trough concentration and liver injury in elderly patients with lung invasive aspergillosis

open access: yesDi-san junyi daxue xuebao, 2020
Objective To investigate the relationship between voriconazole trough concentration and liver injury in elderly patients with lung invasive aspergillosis.
CHENG Lin   +3 more
doaj   +1 more source

Therapeutic Drug Monitoring of Sputum Voriconazole in Pulmonary Aspergillosis

open access: yesPharmaceutics, 2022
Voriconazole is one of the most used antifungal azoles against pulmonary aspergillosis. Therapeutic drug monitoring (TDM) of the voriconazole concentration in plasma is recommended in clinical practice guidelines to prevent treatment failure and toxicity.
Sacha Sarfati   +7 more
doaj   +1 more source

Voriconazole-induced periostitis [PDF]

open access: yesCanadian Medical Association Journal, 2015
A 66-year-old woman with a two-year history of T-cell prolymphocytic leukemia presented with left shoulder pain of 10 months’ duration. A month before the admission, the pain became severe, constant and disabling.
Ines Colmegna, Tetiana Glushko
openaire   +3 more sources

Sustained-release voriconazole-thermogel for subconjunctival injection in horses: ocular toxicity and in-vivo studies

open access: yesBMC Veterinary Research, 2020
Background Keratomycosis is a relatively common, sight threatening condition in horses, where treatment is often prolonged and costly. Subconjunctival (SCo) injections offer less resistance to drug diffusion than the topical route, resulting in better ...
Mariano Mora-Pereira   +7 more
doaj   +1 more source

Comparative study of posaconazole and voriconazole for primary antifungal prophylaxis in patients with pediatric acute leukemia

open access: yesScientific Reports, 2023
Posaconazole and voriconazole are commonly used for preventing invasive fungal disease (IFD), but few studies compared posaconazole with voriconazole for primary antifungal prophylaxis (PAP) in pediatric acute leukemia.
Songji Tu   +5 more
doaj   +1 more source

Predictors of Adverse Events and Determinants of the Voriconazole Trough Concentration in Kidney Transplantation Recipients

open access: yesClinical and Translational Science, 2021
Voriconazole is the mainstay for the treatment of invasive fungal infections in patients who underwent a kidney transplant. Variant CYP2C19 alleles, hepatic function, and concomitant medications are directly involved in the metabolism of voriconazole ...
Yi‐Chang Zhao   +9 more
doaj   +1 more source

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