Results 21 to 30 of about 27,626 (220)
(1) Background: To explore the impact of the degree of inflammation on voriconazole exposure in critically ill patients affected by COVID-associated pulmonary aspergillosis (CAPA); (2) Methods: Critically ill patients receiving TDM-guided voriconazole ...
Milo Gatti+6 more
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The pharmacokinetics of voriconazole [PDF]
Voriconazole (Vfend® Pfizer Global Research and Development, Sandwich, Kent, UK) is a broad-spectrum antifungal triazole that is structurally related to fluconazole. As with all triazole antifungal agents, voriconazole works principally by inhibition of cytochrome P450 14-α-demethylase (P450 14DM) [1, 2].
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Voriconazole-induced periostitis
Voriconazole is a fluorinated drug from the triazole group that is widely used in the prophylaxis and treatment of fungal infections in immunosuppressed patients. Chronic use of this medication can generate, as an adverse effect, a multifocal, asymmetric, diffuse and nodular periosteal reaction, associated with severe and disabling skeletal pain and ...
D.C. Fernández Ávila+7 more
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Objective To investigate the relationship between voriconazole trough concentration and liver injury in elderly patients with lung invasive aspergillosis.
CHENG Lin+3 more
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Therapeutic Drug Monitoring of Sputum Voriconazole in Pulmonary Aspergillosis
Voriconazole is one of the most used antifungal azoles against pulmonary aspergillosis. Therapeutic drug monitoring (TDM) of the voriconazole concentration in plasma is recommended in clinical practice guidelines to prevent treatment failure and toxicity.
Sacha Sarfati+7 more
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Voriconazole-induced periostitis [PDF]
A 66-year-old woman with a two-year history of T-cell prolymphocytic leukemia presented with left shoulder pain of 10 months’ duration. A month before the admission, the pain became severe, constant and disabling.
Ines Colmegna, Tetiana Glushko
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Background Keratomycosis is a relatively common, sight threatening condition in horses, where treatment is often prolonged and costly. Subconjunctival (SCo) injections offer less resistance to drug diffusion than the topical route, resulting in better ...
Mariano Mora-Pereira+7 more
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Posaconazole and voriconazole are commonly used for preventing invasive fungal disease (IFD), but few studies compared posaconazole with voriconazole for primary antifungal prophylaxis (PAP) in pediatric acute leukemia.
Songji Tu+5 more
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Voriconazole is the mainstay for the treatment of invasive fungal infections in patients who underwent a kidney transplant. Variant CYP2C19 alleles, hepatic function, and concomitant medications are directly involved in the metabolism of voriconazole ...
Yi‐Chang Zhao+9 more
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