Results 81 to 90 of about 47,572 (272)

Voriconazole Compared with Liposomal Amphotericin B for Empirical Antifungal Therapy in Patients with Neutropenia and Persistent Fever [PDF]

, 2002
Background Patients with neutropenia and persistent fever are often treated empirically with amphotericin B or liposomal amphotericin B to prevent invasive fungal infections.
Donowitz, Gerald, Greenberg, Richard, Lazarus, Hillard M., Lee, Jeanette, Pappas, Peter, Petersen, Finn, Raffalli, John, Stiff, Patric, Walsh, Thomas J., Winston, Drew J., Yanovich, Saul   +10 more
core   +2 more sources

EUCAST Technical Note on voriconazole [PDF]

Clinical Microbiology and Infection, 2008
Contains fulltext : 70467.pdf (Publisher’s version ) (Open Access)
Rodriguez-Tudela, J.L., Donnelly, J.P., Arendrup, M.C., Arikan, S., Barchiesi, F., Bille, J., Chryssanthou, E., Cuenca-Estrella, M., Danaoui, E., Denning, D.W., Fegeler, W., Gaustad, P., Lass-Florl, C., Moore, C., Richardson, M., Schmalreck, A., Velegraki, J.A., Verweij, P.E.   +17 more
openaire   +4 more sources

Insights Into Patient‐Level Exposure to Actionable Pharmacogenomic Medications in Australia Using a New National Pharmacogenomic Guideline

Clinical Pharmacology &Therapeutics, EarlyView.
This study assessed the use of 35 pharmacogenomic (PGx) medications listed in the Royal College of Pathologists of Australasia (RCPA) guideline, estimated the potential costs of subsidizing PGx testing in Australia, and predicted related prescribing changes.
Bella D. Ianni, Chin Hang Yiu, Mohammad A. Ali, Christine Y. Lu   +3 more
wiley   +1 more source

Candida auris, what do paediatricians need to know? [PDF]

, 2018
AW is supported by the Wellcome Trust Strategic Award (grant 097377) and the MRC Centre for Medical Mycology (grant MR/N006364/1) at the University of Aberdeen.Peer reviewedPublisher ...
Warris, Adilia
core   +1 more source

A strategy for designing voriconazole dosage regimens to prevent invasive pulmonary aspergillosis based on a cellular pharmacokinetics/pharmacodynamics model

Journal of Translational Medicine, 2018
Background Invasive pulmonary aspergillosis (IPA) is a life-threatening disease in immunosuppressed patients. Voriconazole is commonly used to prevent and treat IPA in the clinic, but the optimal prophylactic antifungal regimen is unknown.
Taotao Wang, Tao Zhang, Ti Meng, Ying Li, Lu Chen, Qianting Yang, Haiyan Dong, Jin’e Lei, Limei Chen, Yalin Dong   +9 more
doaj   +1 more source

A Large Retrospective Assessment of Voriconazole Exposure in Patients Treated with Extracorporeal Membrane Oxygenation

Microorganisms, 2021
Background: Voriconazole is one of the first-line therapies for invasive pulmonary aspergillosis. Drug concentrations might be significantly influenced by the use of extracorporeal membrane oxygenation (ECMO).
Ruth Van Daele, Britt Bekkers, Mattias Lindfors, Lars Mikael Broman, Alexander Schauwvlieghe, Bart Rijnders, Nicole G. M. Hunfeld, Nicole P. Juffermans, Fabio Silvio Taccone, Carlos Antônio Coimbra Sousa, Luc-Marie Jacquet, Pierre-François Laterre, Eric Nulens, Veerle Grootaert, Haifa Lyster, Anna Reed, Brijesh Patel, Philippe Meersseman, Yves Debaveye, Joost Wauters, Christophe Vandenbriele, Isabel Spriet   +21 more
doaj   +1 more source

Clinical Implementation of Pharmacogenomics and Drug–Drug Interaction Screening in a German Academic Teaching Hospital and Outpatient Follow‐Up

Clinical Pharmacology &Therapeutics, EarlyView.
Overview of the implemented pharmacogenomics (PGx) process in clinical routine at the Robert Bosch Hospital: from patient enrollment via the hospital information system, DNA detection using a customized TaqMan OpenArray panel and qPCR for CNV assessment, to clinical translation of genotyping results into PGx guideline‐based recommendations using a ...
Roman Tremmel, Filippa Schreeck, Simon Jaeger, Severin Schricker, Elke Schaeffeler, Svitlana Igel, Daniela Steinberger, Manuel Pagitz, Jörg Latus, Markus Ketteler, Kerstin Bühl, Marc‐H. Dahlke, Hans‐Georg Kopp, Matthias Schwab   +13 more
wiley   +1 more source

Association between voriconazole-induced visual hallucination and dopamine in an analysis of the food and drug administration (FDA) adverse event reporting system database

Scientific Reports
Voriconazole is a second-generation azole used to treat serious fungal infections. Visual hallucinations constitute a representative adverse event caused by voriconazole. However, its mechanism of action remains unclear. In patients with schizophrenia or
Hideo Kato, Chihiro Shiraishi, Mao Hagihara, Hiroshige Mikamo, Takuya Iwamoto   +4 more
doaj   +1 more source

Voriconazole-induced hypokalemia and hyponatremia and their correlations with voriconazole trough concentration

Di-san junyi daxue xuebao, 2020
Objective To investigate the incidence rates of voriconazole-induced hypokalemia and hyponatremia and their correlations with voriconazole trough concentration in the patients with lung invasive aspergillosis.
CHENG Lin, WENG Bangbi, XIANG Rongfeng, XIA Peiyuan   +3 more
doaj   +1 more source

Electronic Patient File‐Embedded Model‐Informed Precision Dosing Compared with Physician Dosing of Tacrolimus in Kidney Transplantation

Clinical Pharmacology &Therapeutics, EarlyView.
Model‐informed precision dosing (MIPD) of tacrolimus in renal allograft recipients, evaluated in silico, demonstrated improved (time to and) probability of target concentration attainment and smaller deviations from target range. Using simulated tacrolimus concentration‐time profiles, a study of 200 patients was predicted to have sufficient power to ...
Dirk R.J. Kuypers, Pieter Annaert, Borefore Jallah, Maarten Naesens, Maxine Teuns, Annouschka Laenen, Ruben Faelens   +6 more
wiley   +1 more source