Results 71 to 80 of about 25,862 (171)

Evaluation of the tacrolimus drug interaction with voriconazole vs clotrimazole in heart transplant recipients

JHLT Open
Antifungal prophylaxis postheart transplant (HT) may include voriconazole or clotrimazole, which interact with tacrolimus. There is no guidance for tacrolimus adjustment when transitioning from voriconazole to clotrimazole; therefore, this study ...
Elizabeth Posney, PharmD, Chelsea Barry, PharmD, Nathan J. Verlinden, PharmD, Tara Veasey, PharmD   +3 more
doaj   +1 more source

Voriconazole is a safe and effective anti-fungal prophylactic agent during induction therapy of acute myeloid leukemia

Indian Journal of Medical and Paediatric Oncology, 2016
Background: Antifungal prophylaxis (AFP) reduces the incidence of invasive fungal infections (IFIs) during induction therapy of acute myeloid leukemia (AML). Posaconazole is considered the standard of care.
Akash Shah, Prasanth Ganesan, Venkatraman Radhakrishnan, Krishnarathinam Kannan, Rejiv Rajendranath, Vandana Mahajan, Varalakshmi Vijayakumar, Trivadi Ganesan, Tenali Gnana Sagar   +8 more
doaj   +1 more source

Phytochemical Characterization and Bioactive Potential of Stachys germanica L.: LC–MS/MS Profiling and Multi‐Target Biological Activities

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
The 80% ethanolic extract of Stachys germanica L. exhibited a phenolic‐rich phytochemical profile characterized by chlorogenic acid, naringin, luteolin, and kaempferol. The extract demonstrated notable antioxidant capacity, selective tyrosinase and α‐glucosidase inhibition, and significant antibacterial activity against Acinetobacter baumannii ATCC ...
Gözde Gülin İnan, Derya Doğanay, Yiğit İnan, Selin Akyüz‐Çetin, Neşet Neşetoğlu, İbrahim Daniş, Esra Mertoğlu, Durişehvar Özer Ünal, Gokhan Zengin   +8 more
wiley   +1 more source

From Oral Candidiasis to Candidemia: A Review of Superficial to Invasive Progression

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Recent and limited evidence indicates that oral candidiasis can disseminate Candida albicans throughout the body, leading to invasive candidiasis, such as candidemia, a life‐threatening infection. Considering antifungal resistance and global outbreaks of emergent non‐albicans Candida and related yeasts, murine models help understand dissemination ...
Julia Robledo Jerez, Marcella Vieira Ambrosio, Marcela Eduarda Olegario Fernandes, Ewerton Garcia de Oliveira Mima   +3 more
wiley   +1 more source

Bronchoscopic Removal of Aspergilloma in a 26‐Year‐Old Man

Respirology Case Reports, Volume 14, Issue 8, August 2026.
A 26‐year‐old man with posttuberculous aspergilloma and a prior contralateral pneumonectomy remained refractory to voriconazole but was ineligible for surgery. The friable fungal ball was fragmented and completely extracted bronchoscopically over two sessions using progressively larger bronchoscopes, forceps, a Fogarty catheter and suction.
Chun‐Hao Wang, Lih‐Yu Chang, Jann‐Yuan Wang   +2 more
wiley   +1 more source

Risk factors for voriconazole-associated hepatotoxicity in patients with liver dysfunction: a retrospective nested case–control study

Frontiers in Pharmacology
IntroductionVoriconazole is widely used to prevent and treat invasive aspergillosis. However, its use is restricted by adverse effects, including acute liver injury (ALI).
Jing Ren, Xinfeng Cai, Wei Ge, Jinlin Guo, Shan Wang, Qinhui Wang, Linna Liu, Le Yang, Qi Yang   +8 more
doaj   +1 more source

A Suspected Case of Allergic Bronchopulmonary Mycosis Associated With Exophiala dermatitidis

Respirology Case Reports, Volume 14, Issue 8, August 2026.
An 83‐year‐old man without asthma developed allergic bronchopulmonary mycosis (ABPM) associated with Exophiala dermatitidis. This case suggests that E. dermatitidis may be involved in ABPM. ABSTRACT Exophiala dermatitidis is a black fungus that can colonize the airways, but allergic bronchopulmonary mycosis (ABPM) associated with E.
Toshiyuki Yonezawa, Saori Onishi, Daisuke Sunakawa, Yasutaka Kato, Satoru Ito   +4 more
wiley   +1 more source

Microenvironment‐Responsive Drug Delivery Systems for Ocular Surface Diseases: Mechanisms, Applications, and Translational Challenges

Small Science, Volume 6, Issue 8, August 2026.
Microenvironment‐responsive drug delivery systems overcome ocular physiological barriers by responding to temperature, pH, ions, reactive oxygen species, and enzymes. This review bridges material design, performance evaluation, and clinical translation, offering actionable insights for treating dry eye disease, infectious keratitis, and corneal ...
Jiamin Liu, Liangbo Chen, Yao Fu, Siyi Zhang   +3 more
wiley   +1 more source

CYP2C19 c.681G>A Is not in Complete Linkage Disequilibrium With c.332‐23A>G: Implications for Pharmacogenetic Testing

Clinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT CYP2C19 plays an important role in the metabolism of many medications, including the antiplatelet agent clopidogrel, the antifungal agent voriconazole, selective serotonin reuptake inhibitors, select tricyclic antidepressants, and proton pump inhibitors.
Amy J. Turner, Erin C. Boone, Cyrine E. Haidar, Wenjian Yang, Ashley D. Derezinski, Andrew Haddad, Philip E. Empey, Ulrich Broeckel, Andrea Gaedigk   +8 more
wiley   +1 more source

Neurologic Adverse Events Associated with Voriconazole Therapy: Report of Two Pediatric Cases

Case Reports in Infectious Diseases, 2016
Although voriconazole, a triazole antifungal, is a safe drug, treatment with this agent is associated with certain adverse events such as hepatic, neurologic, and visual disturbances.
Sevliya Öcal Demir, Serkan Atici, Gülşen Akkoç, Nurhayat Yakut, Nilay Baş İkizoğlu, Ela Erdem Eralp, Ahmet Soysal, Mustafa Bakir   +7 more
doaj   +1 more source