Results 81 to 90 of about 43,106 (210)

Development of a Highly Efficient CRISPR/Cas9-Mediated Herpesvirus of Turkey-Based Vaccine against Novel Variant Infectious Bursal Disease Virus

Vaccines
Infectious bursal disease (IBD), caused by IBD virus (IBDV), is an extremely contagious immunosuppressive disease that causes major losses for the poultry industry worldwide.
Jun-Feng Zhang, Jong-Yeol Park, Sang-Won Kim, Yu-Ri Choi, Se-Yeoun Cha, Hyung-Kwan Jang, Bai Wei, Min Kang   +7 more
doaj   +1 more source

Apoptosis pathways induced by recombinant adenovirus in cancer cells [PDF]

, 2010
Apoptosis, or programmed cell death, is an essential physiological process that plays a critical role in development and tissue homeostasis. Expression of VP2 gene derived from infectious bursal disease virus (IBDV) has been shown to be able to induce ...
Allaudin, Zeenathul Nazariah, Koh, Choo Yan   +1 more
core  

Sero‐Epidemiology and Molecular Detection of Bluetongue Virus in Goats in Bangladesh

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
The first large‐scale study in Bangladesh confirmed bluetongue virus infection in goats through combined c‐ELISA and nested RT‐PCR approaches, revealing high seroprevalence and identifying key management‐related risk factors. ABSTRACT Background Bluetongue (BT) is an arthropod‐transmitted, non‐contagious viral disease of domestic ruminants caused by ...
Md Habibur Rahman, Md Nurul Haque, Md Zulfekar Ali, Lutfun Naher, Md Zakir Hassan, Sadek Ahmed   +5 more
wiley   +1 more source

Generation of Recombinant Porcine Parvovirus Virus-Like Particles in Saccharomyces cerevisiae and Development of Virus-Specific Monoclonal Antibodies

Journal of Immunology Research, 2014
Porcine parvovirus (PPV) is a widespread infectious virus that causes serious reproductive diseases of swine and death of piglets. The gene coding for the major capsid protein VP2 of PPV was amplified using viral nucleic acid extract from swine serum and
Paulius Lukas Tamošiūnas, Rasa Petraitytė-Burneikienė, Rita Lasickienė, Artiomas Akatov, Gabrielis Kundrotas, Vilimas Sereika, Raimundas Lelešius, Aurelija Žvirblienė, Kęstutis Sasnauskas   +8 more
doaj   +1 more source

Virus and host factors affecting the clinical outcome of bluetongue virus infection [PDF]

, 2014
Bluetongue is a major infectious disease of ruminants caused by bluetongue virus (BTV), an arbovirus transmitted by Culicoides. Here, we assessed virus and host factors influencing the clinical outcome of BTV infection using a single experimental ...
Caporale, Marco, Di Gialleonorado, Luigina, Di Ventura, Mauro, Janowicz, Anna, Mertens, Peter, Palmarini, Massimo, Savini, Giovanni, Shaw, Andrew, Van Rijn, Piet A., Wilkie, Gavin   +9 more
core   +3 more sources

Identification and Phylogenetic Characterisation of Novel Adeno‐Associated Virus Capsids in Non‐Human Primate Tissues

Cell Proliferation, Volume 59, Issue 5, May 2026.
AAV's widespread application is currently confronting critical challenges. This study established a systematic framework of ‘natural discovery–evolutionary analysis–functional optimization’, providing a new paradigm for the development of next‐generation AAV vectors with clinical‐grade tissue specificity, low immunogenicity, and cross‐species ...
Liyu Zhu, Kai Xu, Yali Ding, Kailun Liu, Jing Liu, Zongren Hou, Rui Niu, Ning Yang, Hualing Qin, Baoyang Hu, Ying Zhang, Wei Li   +11 more
wiley   +1 more source

Advances in the Treatment of Sensorineural Hearing Loss: From Traditional Therapies to Stem Cell and Gene Therapies

Advanced Sensor Research, Volume 5, Issue 4, April 2026.
Sensorineural hearing loss (SNHL) occurs in 1.5 billion globally, primary driven by damage of cochlear hair cells and spiral ganglion neurons. This review systematically examines current therapeutic strategies for sensorineural hearing loss, including traditional drug and physical therapies as well as emerging stem cell and gene therapies, providing a ...
Ruirui Chen, Yang Zhang, Zhe Li, Renjie Chai   +3 more
wiley   +1 more source

Canine parvovirus (CPV-2) variants circulating in Nigerian dogs [PDF]

, 2016
Canine parvovirus type 2 (CPV-2) is a highly contagious viral disease with three variants (CPV-2a, CPV-2b and CPV-2c) currently circulating in dogs worldwide.
Apaa, Ternenge, Daly, Janet M., Tarlinton, Rachael E.   +2 more
core   +2 more sources

Mechanical Strain‐Programmed SDC1+ Sheath Fibroblasts Trigger CXCR4hi Neutrophil‐Mediated Enthesitis in Ankylosing Spondylitis

Advanced Science, Volume 13, Issue 21, 13 April 2026.
In ankylosing spondylitis (AS), mechanical strain‐programmed SDC1+ sheath fibroblasts secrete CXCL5 to recruit neutrophils and promote the activation of CXCR4hi neutrophils, thereby exacerbating enthesitis by promoting neutrophil extracellular traps (NETs) formation. SOX5 controls the generation of SDC1+ sheath fibroblasts via super‐enhancers.
Jiajie Lin, Zepeng Su, Yipeng Zeng, Yi Zhou, Chenying Zeng, Weihao Zhang, Qibo Li, Zipeng Xiao, Zibin Chen, Ziqian Liu, Yangfeng Lin, Guan Zheng, Wenhui Yu, Zhongyu Xie   +13 more
wiley   +1 more source

Truncated forms of viral VP2 proteins fused to EGFP assemble into fluorescent parvovirus-like particles [PDF]

, 2006
Fluorescence correlation spectroscopy (FCS) monitors random movements of fluorescent molecules in solution, giving information about the number and the size of for example nano-particles. The canine parvovirus VP2 structural protein as well as N-terminal
Leona Gilbert, Jouni Toivola, Outi Välilehto, Taija Saloniemi, Claire Cunningham, Daniel White, Anna R Mäkelä, Eila Korhonen, Matti Vuento, Christian Oker-Blom   +9 more
core   +1 more source