Sulfated Lactosyl Archaeol Archaeosome-Adjuvanted Vaccine Formulations Targeting Rabbit Hemorrhagic Disease Virus Are Immunogenic and Efficacious [PDF]
Vaccines, 2023 Vaccines play an important role in maintaining human and animal health worldwide. There is continued demand for effective and safe adjuvants capable of enhancing antigen-specific responses to a target pathogen.
Bassel Akache +16 more
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First report of GI.1aP-GI.2 recombinants of rabbit hemorrhagic disease virus in domestic rabbits in China [PDF]
Frontiers in Microbiology, 2023 The rabbit hemorrhagic disease virus 2 (RHDV2 or GI.2) is a highly contagious agent leading to lethal disease in rabbits. It frequently recombines with other Lagovirus genus, generating epidemical variants with high pathogenicity.
Yan Li +8 more
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Novel Recombinant Rabbit Hemorrhagic Disease Virus 2 (RHDV2) is Circulating in China within 12 Months after Original RHDV2 Arrival. [PDF]
Transbound Emerg Dis, 2023 Rabbit hemorrhagic disease (RHD) causes lethal fulminant hepatitis in rabbits. Two different genotypes (GI.1 and GI.2) responsible for RHD are reported. GI.2 was first detected in France in 2010 and subsequently spread to other countries in Europe. In April 2020, GI.2 was detected in China.
Hu B +9 more
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Phylogenetic Analysis of European Brown Hare Syndrome Virus Strains from Poland (1992–2004) [PDF]
Viruses, 2021 European brown hare syndrome (EBHS) is lethal to several species of free-living hares worldwide. The genetic characterization of its virus (EBHSV) strains in European circulation and epidemiological knowledge of EBHSV infections is not yet complete.
Andrzej Fitzner +5 more
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The Baculovirus Expression System Expresses Chimeric RHDV VLPs as Bivalent Vaccine Candidates for Classic RHDV (GI.1) and RHDV2 (GI.2) [PDF]
VaccinesBackground: Rabbit hemorrhagic disease (RHD) is an acute, hemorrhagic and highly lethal infectious disease caused by rabbit hemorrhagic disease virus (RHDV), which causes huge economic losses to the rabbit breeding industry.
Yan Wang +6 more
doaj +2 more sources
One misdated sequence of rabbit hemorrhagic disease virus prevents accurate estimation of its nucleotide substitution rate [PDF]
BMC Evolutionary Biology, 2012 Background The literature is ripe with phylogenetic estimates of nucleotide substitution rates, especially of measurably evolving species such as RNA viruses.
Hicks Allison L, Duffy Siobain
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Genetic Characteristics and Phylogeographic Dynamics of Lagoviruses, 1988–2021 [PDF]
Viruses, 2023 Rabbit haemorrhagic disease virus (RHDV), European brown hare syndrome virus (EBHSV), rabbit calicivirus (RCV), and hare calicivirus (HaCV) belong to the genus Lagovirus of the Caliciviridae family that causes severe diseases in rabbits and several hare (
Pir Tariq Shah +6 more
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Specific Detection of RHDV GI.1 and GI.2 by RT-LAMP-CRISPR/Cas12a Platform. [PDF]
Transbound Emerg DisRabbit hemorrhagic disease is a highly contagious and acute fatal disease caused by rabbit hemorrhagic disease virus (RHDV). The first outbreak of RHDV2 in 2020 has posed a serious threat to the rabbit breeding industry in China. An effective and specific detection strategy for RHDV GI.1 (RHDV1) and GI.2 (RHDV2) is urgently needed.
Wu M +9 more
europepmc +2 more sources
, 2017 为了构建表达兔瘟病毒VP60基因的牛疱疹病毒I型，首先构建含有兔瘟病毒VP60基因和CMV启动子的转移载体，然后将构建移载体与gE基因缺失的牛疱疹病毒I型基因组共转染牛肺细胞后收获增殖的病毒。通过蓝白斑筛选不含有LacZ基因的白色病毒蚀斑，反复纯化获得重组病毒BHV-1-VP60。PCR方法验证VP60基因的成功插入，间接免疫荧光试验和Western blot，结果证明了BHV-1-VP60中的VP60基因在易感细胞中获得了表达。本研究成功地构建了兔瘟病毒VP60基因的重组病毒BHV-1-VP60 ...
D. Yuan +5 more
semanticscholar +2 more sources
Epitope mapping of a neutralizing antibody against rabbit hemorrhagic disease virus GI.2 [PDF]
Veterinary ResearchIn 2010, rabbit hemorrhagic disease virus (RHDV) GI.2 emerged, and unlike RHDV GI.1, it caused mortality in young rabbits, while existing vaccines were not fully protective.
Ana Podadera +7 more
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