Emergence of rabbit haemorrhagic disease virus 2 in China in 2020
Veterinary Medicine and Science, Volume 7, Issue 1, Page 236-239, January 2021., 2021 The first outbreak of rabbit hemorrhagic disease induced by rabbit hemorrhagic disease virus 2 (GI.2) in China. Abstract Rabbit haemorrhagic disease (RHD) is an acute fatal disease caused by the Lagovirus rabbit haemorrhagic disease virus (RHDV), which was first reported in 1984 in China.
Bo Hu +9 more
wiley +1 more source
Ruptura mecánica de la levadura Pichia pastoris para la extracción de la proteína recombinante VP60
, 2021 El sistema de expresi n de la levadura metilotr fica Pichia pastoris ha sido ampliamente empleado en la obtenci n de prote nas recombinantes con fines terap uticos, entre las que se encuentra la prote na VP60 como principio activo del candidato vacunal contra la fiebre hemorr gica del conejo.
Ainerys Vázquez-Guerra +10 more
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Atomic model of rabbit hemorrhagic disease virus by cryo-electron microscopy and crystallography. [PDF]
PLoS Pathogens, 2013 Rabbit hemorrhagic disease, first described in China in 1984, causes hemorrhagic necrosis of the liver. Its etiological agent, rabbit hemorrhagic disease virus (RHDV), belongs to the Lagovirus genus in the family Caliciviridae.
Xue Wang +12 more
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Construction and Identification of Recombinant Virus BHV-1 Expression of VP60 Gene of RHDV
Immunology Studies, 2017 为了构建表达兔瘟病毒VP60基因的牛疱疹病毒I型，首先构建含有兔瘟病毒VP60基因和CMV启动子的转移载体，然后将构建移载体与gE基因缺失的牛疱疹病毒I型基因组共转染牛肺细胞后收获增殖的病毒。通过蓝白斑筛选不含有LacZ基因的白色病毒蚀斑，反复纯化获得重组病毒BHV-1-VP60。PCR方法验证VP60基因的成功插入，间接免疫荧光试验和Western blot，结果证明了BHV-1-VP60中的VP60基因在易感细胞中获得了表达。本研究成功地构建了兔瘟病毒VP60基因的重组病毒BHV-1-VP60，为研制新型兔瘟活载体疫苗奠定了基础。 In order to construct the recombinant bovine heper virus I which expressed RHDV ...
冬伟 原
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Confirmation of the Rabbit Hemorrhagic Disease Virus Type 2 (GI.2) Circulation in North Africa
Acta Veterinaria, 2022 Rabbit hemorrhagic disease (RHD) is a highly contagious viral disease that causes fatal acute hepatitis in domestic and wild lagomorphs. It has taken on major economic importance in countries like Morocco.
Saidi Aissa, Aboutaib Abdelouahed
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Detection and differentiation of rabbit hemorrhagic disease and European brown hare syndrome viruses by amplification of VP60 genomic sequences from fresh and fixed tissue specimens [PDF]
Journal of Clinical Microbiology, 1997 Two reverse transcription-PCR (RT-PCR) assays have been developed for the detection and differentiation of rabbit hemorrhagic disease virus (RHDV) and European brown hare syndrome virus (EBHSV), two closely related caliciviruses. In order to select highly specific primers, comparative analysis was performed with a large number of RHDV and EBHSV genomic
Carlos Ros +2 more
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Nucleolin mediates the internalization of rabbit hemorrhagic disease virus through clathrin-dependent endocytosis. [PDF]
PLoS Pathogens, 2018 Rabbit hemorrhagic disease virus (RHDV) is an important member of the Caliciviridae family and a highly lethal pathogen in rabbits. Although the cell receptor of RHDV has been identified, the mechanism underlying RHDV internalization remains unknown.
Jie Zhu +8 more
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Detection of positive selection in the major capsid protein VP60 of the rabbit haemorrhagic disease virus (RHDV) [PDF]
Virus Research, 2008 Mutations were analysed in the major capsid protein VP60 of the rabbit haemorrhagic disease virus (RHDV), a calicivirus responsible for high mortality rates in both wild and domestic European rabbits (Oryctolagus cuniculus). Likelihood of positive selection was estimated using the PAML software applied to 43 non-identical complete sequences of the ...
Pedro J. Esteves +6 more
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Phylogenetic Analysis of Selected RHDV Strains on the Basis of a Fragment of the Gene Encoding C-Terminal End of VP60 Capsid Structural Protein [PDF]
Journal of Phylogenetics & Evolutionary Biology, 2014 Phylogenetic analyses of RHDV provide information on the affinity of strains and point to evolutionary dependencies among them. The objective of the study was the phylogenetic analysis of six strains of RHD virus, including four Czech strains (CAMPV-351, CAMPV-561, CAMPV-562, CAMPV-558) and two French strains (Fr-1, Fr-2), on the basis of a fragment of
Beata Tokarz Deptuła
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RHDV2 epidemic in UK pet rabbits. Part 2: PCR results and correlation with vaccination status
Journal of Small Animal Practice, Volume 61, Issue 8, Page 487-493, August 2020., 2020 Objective To report PCR results and vaccination status of rabbits with rabbit haemorrhagic disease following an investigation into sudden or unexpected death. Materials and Methods PCR testing for RHDV2 and RHDV1 was performed on rabbit liver samples at two laboratories.
F. M. Harcourt‐Brown +2 more
wiley +1 more source