Results 61 to 70 of about 792 (161)

Plant‐based oral vaccines against zoonotic and non‐zoonotic diseases

Plant Biotechnology Journal, Volume 14, Issue 11, Page 2079-2099, November 2016., 2016
Summary The shared diseases between animals and humans are known as zoonotic diseases and spread infectious diseases among humans. Zoonotic diseases are not only a major burden to livestock industry but also threaten humans accounting for >60% cases of human illness.
Naila Shahid, Henry Daniell
wiley   +1 more source

RHDV VP60 interacted with the N-terminal domain of NCL.

, 2018
(A) NCL binds to VP60 during RHDV internalization. An IP assay was performed on cell lysates using NCL mAb in RK-13 cells that were infected or uninfected with mRHDV, then immunoblotted with mAbs against NCL or VP60.
Xiaoxue Wang (311457), Jingyu Tang (5874017), Dandan Dong (160546), Ruibin Qi (5874020), Guangqing Liu (411371), Qiuhong Miao (829515), Jie Zhu (126574), Teng Liu (232251), Zhibiao Yang (368892)   +8 more
core   +1 more source

Plant‐Based Vaccines: Production and Challenges

Journal of Botany, Volume 2016, Issue 1, 2016., 2016
Plant‐based vaccine technologies involve the integration of the desired genes encoding the antigen protein for specific disease into the genome of plant tissues by various methods. Agrobacterium‐mediated gene transfer and transformation via genetically modified plant virus are the common methods that have been used to produce effective vaccines ...
Erna Laere, Anna Pick Kiong Ling, Ying Pei Wong, Rhun Yian Koh, Mohd Azmi Mohd Lila, Sobri Hussein, Maria R. Ercolano   +6 more
wiley   +1 more source

Farming of Plant‐Based Veterinary Vaccines and Their Applications for Disease Prevention in Animals

Advances in Virology, Volume 2015, Issue 1, 2015., 2015
Plants have been studied for the production of pharmaceutical compounds for more than two decades now. Ever since the plant‐made poultry vaccine against Newcastle disease virus made a breakthrough and went all the way to obtain regulatory approval, research to use plants for expression and delivery of vaccine proteins for animals was intensified ...
Pit Sze Liew, Mohd Hair-Bejo, Jay C. Brown   +2 more
wiley   +1 more source

MOLECULAR AND HISTOPATHOLOGICAL DETECTION OF RABBIT HEMORRHAGIC DISEASE VIRUS IN YOUNG RABBITS [PDF]

Kafrelsheikh Veterinary Medical Journal, 2011
Calicivirus infection causes rabbit haemorrhagic disease (RHD) that kills more than 90% of adult animals, whereas young rabbits are naturally resistant to this viral disease.
E.M. El-Nahas
doaj   +1 more source

Crystal structures of the S and P domains of RHDV major capsid protein VP60.

, 2013
(A) Domain organization of VP60. (B) Ribbon representation of the crystal structure of the VP60 S domain showing the classic viral, BIDG-CHEF β-barrel motif.
Timothy S. Baker (102846), Dong Zheng (102852), Hai Pang (102853), Klaus Schulten (102849), Jiasen Liu (102834), Fei Sun (102854), Yanxin Liu (102838), Yujia Zhai (102840), Jun Ma (9393), Xue Wang (102830), Fengting Xu (102832), Bingquan Gao (102836), Kai Zhang (102844)   +12 more
core   +1 more source

Multi-target chimaeric VLP as a therapeutic vaccine in a model of colorectal cancer

Journal for ImmunoTherapy of Cancer, 2017
Background Colorectal cancer is responsible for almost 700,000 deaths annually worldwide. Therapeutic vaccination is a promising alternative to conventional treatment for colorectal cancer, using vaccines to induce targeted immune responses against ...
Braeden Donaldson, Farah Al-Barwani, Simon J. Pelham, Katie Young, Vernon K. Ward, Sarah L. Young   +5 more
doaj   +1 more source

The P1s domain of the RHDV VP60 protein contains a conserved sequence motif that binds to the NCL NTD domain.

, 2018
(A) Sequence alignment showing the location of aa substitutions introduced into the GST-tagged VP60-P1s-C1. (B) Western blot analysis of the glutathione affinity pull-down assays using GST-tagged VP60-P1s-C1 mutants as the bait and NCL expressed in RK-13
Xiaoxue Wang (311457), Jingyu Tang (5874017), Dandan Dong (160546), Ruibin Qi (5874020), Guangqing Liu (411371), Qiuhong Miao (829515), Jie Zhu (126574), Teng Liu (232251), Zhibiao Yang (368892)   +8 more
core   +1 more source

IDENTIFICATION AND CHARACTERIZATION OF THE CURRENTLY CIRCULATING RABBIT HEMORRHAGIC DISEASE VIRUS ISOLATES [PDF]

Assiut Veterinary Medical Journal
Even among vaccinated rabbits, the virus that causes rabbit viral hemorrhagic disease (RHDV) has been increasing in Egypt recently. So, the current study screened the emergent RHDV of vaccinated and unvaccinated domestic rabbits in some Egyptian ...
DOHA AHMED, SAMAH ALI ABODALAL, MOSTAFA SAIFELDIN, RAGAB IBRAHIM, OMAR AMEN   +4 more
doaj   +1 more source

Improved Production Efficiency of Virus-Like Particles by the Baculovirus Expression Vector System. [PDF]

PLoS ONE, 2015
Vaccines based on virus-like particles (VLPs) have proven effective in humans and animals. In this regard, the baculovirus expression vector system (BEVS) is one of the technologies of choice to generate such highly immunogenic vaccines. The extended use
Javier López-Vidal, Silvia Gómez-Sebastián, Juan Bárcena, Maria del Carmen Nuñez, Diego Martínez-Alonso, Benoit Dudognon, Eva Guijarro, José M Escribano   +7 more
doaj   +1 more source