Results 71 to 80 of about 1,200 (174)

Molecular characterization of rabbit hemorrhagic disease virus type 2 and long-lasting protection conferred by a VLP-based vaccine

BMC Veterinary Research
Background Rabbit hemorrhagic disease virus (RHDV) type 2 (GI.2) is an emerging pathogen genetically distinct from classic RHDV (GI.1). It can infect young, wild, and even vaccinated rabbits, and may also contract RHD.
Yanhui Wang, Peipei Qiao, Hongchao Wu, Xiaodan Tong, Tongyan Wang, Lu Wang, Yihang Yang, Xiaorui Su, Caihong Liu, Yalei Chen, Lulu Wang, Mengyue Wang, Xiangfeng Xi, Fang Wang, Wenqiang Pang, Yuxiu Liu, Kegong Tian   +16 more
doaj   +1 more source

Multi-target chimaeric VLP as a therapeutic vaccine in a model of colorectal cancer

Journal for ImmunoTherapy of Cancer, 2017
Background Colorectal cancer is responsible for almost 700,000 deaths annually worldwide. Therapeutic vaccination is a promising alternative to conventional treatment for colorectal cancer, using vaccines to induce targeted immune responses against ...
Braeden Donaldson, Farah Al-Barwani, Simon J. Pelham, Katie Young, Vernon K. Ward, Sarah L. Young   +5 more
doaj   +1 more source

Improved Production Efficiency of Virus-Like Particles by the Baculovirus Expression Vector System. [PDF]

PLoS ONE, 2015
Vaccines based on virus-like particles (VLPs) have proven effective in humans and animals. In this regard, the baculovirus expression vector system (BEVS) is one of the technologies of choice to generate such highly immunogenic vaccines. The extended use
Javier López-Vidal, Silvia Gómez-Sebastián, Juan Bárcena, Maria del Carmen Nuñez, Diego Martínez-Alonso, Benoit Dudognon, Eva Guijarro, José M Escribano   +7 more
doaj   +1 more source

Field and experimental data indicate that the eastern cottontail (Sylvilagus floridanus) is susceptible to infection with European brown hare syndrome (EBHS) virus and not with rabbit haemorrhagic disease (RHD) virus [PDF]

, 2017
This is an Open Access article distributed under the terms of the Creative Commons Attribution License.-- et al.The eastern cottontail (Sylvilagus floridanus) is an American lagomorph. In 1966, it was introduced to Italy, where it is currently widespread.
Abrantes, Joana, Esteves, Pedro J., Lavazza, Antonio, Pinheiro, Ana   +3 more
core   +1 more source

Bioinformatics analysis of capsid protein of different subtypes rabbit hemorrhagic disease virus

BMC Veterinary Research, 2019
Background Rabbit Hemorrhagic Disease Virus (RHDV) belongs to the Caliciviridae family, is a highly lethal pathogen to rabbits. Increasing numbers of studies have demonstrated the existence of antigenic variation in RHDV, leading to the emergence of a ...
Ruibin Qi, Jie Zhu, Qiuhong Miao, Aoxing Tang, Dandan Dong, Xiaoxue Wang, Guangqing Liu   +6 more
doaj   +1 more source

An isolated epizootic of hemorrhagic-like fever in cats caused by a novel and highly virulent strain of feline calicivirus. [PDF]

, 2000
An isolated epizootic of a highly fatal feline calicivirus (FCV) infection, manifested in its severest form by a systemic hemorrhagic-like fever, occurred over a 1-month period among six cats owned by two different employees and a client of a private ...
Elliott, JB, Glasgow, A, Keel, K, Pedersen, NC, Poland, A   +4 more
core   +1 more source

Diagnóstico mediante PCR-duplex de la nueva variante RHDVb del virus de la enfermedad hemorrágica en conejos [PDF]

, 2013
Publishe
Calvete Margolles, Carlos, Calvo Lacosta, Jorge Hugo, Calvo, A.J., Monroy, F., Sarto Aured, María Pilar   +4 more
core  

Crystal structure and proteomics analysis of empty virus-like particles of Cowpea mosaic virus [PDF]

, 2016
Empty virus-like particles (eVLPs) of Cowpea mosaic virus (CPMV) are currently being utilized as reagents in various biomedical and nanotechnology applications. Here, we report the crystal structure of CPMV eVLPs determined using X-ray crystallography at
Aljabali, Aljabali, Aljabali, Aljabali, Brunger, Brunger, Buchan, Canizares, CCP4, Cowtan, Dalsgaard, Destito, Emma L. Hesketh, Emsley, Evans, Franssen, Geelen, George P. Lomonossoff, Heinig, Hesketh, John E. Johnson, Jones, Jones, Khayat, Larson, Laskowski, Lebedev, Lin, Linh T. Hoang, McCoy, Montague, Neil A. Ranson, Nhung T. Huynh, Niblett, Niblett, Otwinowski, Pettersen, Pooja Saxena, Porta, Powers, Rae, Sainsbury, Sainsbury, Saunders, Shah, Stauffacher, Steinmetz, Steinmetz, Steinmetz, Tars, Tars, Taylor, Usha, Vijay S. Reddy, Wen, You-Chan Ku, Yulia Meshcheriakova   +56 more
core   +1 more source

Positive selection in the hemagglutinin-neuraminidase gene of Newcastle disease virus and its effect on vaccine efficacy [PDF]

, 2011
Background To investigate the relationship between the selective pressure and the sequence variation of the hemagglutinin-neuraminidase (HN) protein, we performed the positive selection analysis by estimating the ratio of non-synonymous to ...
Min Gu, Wujie Liu, Lijun Xu, Yongzhong Cao, Chunfeng Yao, Shunlin Hu, Xiufan Liu   +6 more
core   +1 more source

Minor structural protein VP2 in rabbit hemorrhagic disease virus downregulates the expression of the viral capsid protein VP60

Journal of General Virology, 2009
Rabbit hemorrhagic disease virus (RHDV) has two structural proteins: the major capsid protein VP60 and the minor capsid protein VP2. VP2 is speculated to play an important role in the virus life cycle. To investigate the effect of VP2 on VP60 expression, three types of experiment (baculovirus–insect cell system, mammalian–luciferase assay system and in
Liu, Chen, Guangqing, Liu, Zheng, Ni, Bin, Yu, Tao, Yun, Yi, Song, Jionggang, Hua, Shuangmao, Li, Jianping, Chen   +8 more
openaire   +2 more sources