Results 61 to 70 of about 16,435 (197)

Predictors of Vancomycin-resistant Enterococcus (VRE) Carriage in the First Major VRE Outbreak in Singapore

Annals of the Academy of Medicine, Singapore, 2007
Introduction: Until recently, vancomycin-resistant enterococcus (VRE) infection or colonisation was a rare occurrence in Singapore. The first major VRE outbreak involving a 1500-bed tertiary care institution in March 2005 presented major challenges in infection control and came at high costs. This study evaluates the predictors of VRE carriage based on
Yang, K.-S., Fong, Y.-T., Lee, H.-Y., Kurup, A., Koh, T.-H., Koh, D., Lim, M.-K.   +6 more
openaire   +2 more sources

Chemical Optimization of Temporin A–L Peptides: From Native Isoforms to Enhanced Antimicrobial Analogs

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
Temporins, among antimicrobial peptides, are short frog‐derived molecules with potent antibacterial activity. This review highlights chemical optimization strategies applied to temporins A–L, showing how sequence tuning modulates structure, stability, and selectivity, enabling improved activity against resistant pathogens.
Ida Boccino, Paolo Grieco, Francesco Merlino   +2 more
wiley   +1 more source

Streptoquinolines A and B, new antibacterial meroterpenoids produced by Streptomyces sp. TMPU-A0679

Beilstein Journal of Organic Chemistry
In the course of screening vancomycin-resistant enterococci (VRE), two new meroterpenoids, streptoquinolines A (1) and B (2), were isolated from a culture of terrestrial Streptomyces sp. TMPU-A0679.
Akiho Yagi, Hitomi Tomura, Ami Konno, Ryuji Uchida   +3 more
doaj   +1 more source

Fragmentation of Vancoresmycin Reveals a Strong Dependence on Global Molecular Architecture for Antibacterial Activity

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
Fragmentation of the natural product vancoresmycin reveals an essential role of global architecture for biological potency. Vancoresmycin is a structurally complex tetramic‐acid‐containing natural product with potent activity against Gram‐positive bacteria, yet its structure–activity relationships remain poorly defined.
Max Schönenbroicher, Florian Heppner, Maximilian Seul, Simon Morgenschweis, Aia Ali Abdelrahman, Eva Fahr, Niklas Holstein, Anna Müller, Dirk Menche   +8 more
wiley   +1 more source

Advances in BODIPY Derivatives for Antibacterial Phototherapy

Angewandte Chemie, Volume 138, Issue 30, 20 July 2026.
This review systematically summarizes the design strategies and structure‐activity relationships of BODIPY‐based antibacterial phototherapy, covering molecular engineering of small‐molecule photosensitizers and nanoplatforms, bacterial targeting and carrier design, and discussing the challenges and future perspectives associated with clinical ...
Li Lv, Heejeong Kim, Hongchen Zhai, Hanqi Ren, Silu Wang, Cong Sun, Yafu Wang, Hosoowi Lee, Juyoung Yoon, Hua Zhang   +9 more
wiley   +2 more sources

Improved Incorporation of Arylglycines Into Ramoplanin Sequences via Solid‐Phase Peptide Synthesis

European Journal of Organic Chemistry, Volume 29, Issue 30, 12 August 2026.
The incorporation of arylglycines using solid‐phase peptide synthesis remains challenging due to the sensitivity of these residues for epimerization. Here, exploring multiple conditions for the incorporation of arylglycine residues into peptides using SPPS demonstrates how small changes to current synthesis protocols can lead to significant ...
Edward Marschall, Sam Tucker, Max J. Cryle, Julien Tailhades   +3 more
wiley   +1 more source

Meningitis Caused by Vancomycin-resistant Enterococcus faecium – A Growing Concern

Current Medical Issues
Meningitis caused by Vancomycin resistant Enterococcus faecium (VRE) is an uncommon but serious nosocomial infection with limited therapeutic options. We report the three cases of VRE meningitis: A postneurosurgical adult with linezolid-resistant VRE, a ...
Aishwarya Babu, Mahadevan Kumar, Abhijeet Mane, Lata Yadav   +3 more
doaj   +1 more source

Antimicrobial Resistance at the Human–Animal–Environment Interface: A One Health Perspective on Drivers, Transmission, and Public Health Responses

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Antimicrobial resistance (AMR) is a global health threat driven by interconnected antimicrobial use and environmental pressures across human, animal, and ecological systems. This review synthesizes current evidence on the major drivers, transmission pathways, reservoirs, surveillance challenges, and public health responses ...
Nurshad Ali
wiley   +1 more source

3D Electrical Impedance Tomography of Regional Ventilation During Jet Ventilation: A Pilot Study

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 4, August 2026.
ABSTRACT Objectives Low‐frequency jet ventilation (LFJV) is commonly used in laryngotracheal surgery when intubation is not feasible. However, limited understanding of regional ventilation and distal airway pressures raises safety concerns and restricts broader adoption.
Daniel S. Fink, Nilton Barbosa da Rosa Jr, Sanghee Cho, Michelle Mellenthin, Andre Vieira Pigatto, Tzu‐Jen Kao, Benjamin Cloyd, Ana Fernandez‐Bustamante, Matthew Clary, Drew Gottman, Ryan Lau, Jennifer L. Mueller   +11 more
wiley   +1 more source

Resolution of a vanA VRE outbreak with no change in vanB VRE [PDF]

Infection, Disease & Health, 2016
Matthew Richards, Kathryn Williams, Louise Hobbs, Caroline Marshall   +3 more
openaire   +1 more source