Results 91 to 100 of about 76,465 (345)

Integration of Genetic and Imaging Data for Alzheimer's Disease Diagnosis and Interpretation

Advanced Science, EarlyView.
AlzCLIP is a novel contrastive learning framework that integrates single nucleotide polymorphism (SNP) profiles and MRI‐derived imaging features into a unified representation space to improve Alzheimer's disease (AD) diagnosis and interpretation. By achieving superior diagnostic accuracy and revealing key genetic and structural contributors to AD risk,
Yanfei Wang, Qing Wang, Minghao Zhou, Jialu Liang, Lei You, Breton Asken, Xiaobo Zhou, Qianqian Song   +7 more
wiley   +1 more source

Beyond the Lumen: Molecular Imaging to Unmask Vulnerable Coronary Plaques

Journal of Cardiovascular Development and Disease
Vulnerable coronary atherosclerotic plaque involves a dynamic pathophysiologic process within and surrounding an atheromatous plaque in coronary artery intima. The process drastically increases the risk of plaque rupture and is clinically responsible for
Geoffrey Currie, Hosen Kiat
doaj   +1 more source

Isolation, culturing and gene expression profiling of inner mass cells from stable and vulnerable carotid atherosclerotic plaques.

PLoS ONE, 2019
The connective tissue components that form the atherosclerotic plaque body are produced by the plaque inner mass cells (PIMC), located inside the plaque.
Olga A Novikova, Zhanna K Nazarkina, Anna V Cherepanova, Petr P Laktionov, Boris P Chelobanov, Ivan S Murashov, Roman V Deev, Evgeny A Pokushalov, Andrey A Karpenko, Pavel P Laktionov   +9 more
doaj   +1 more source

A score including ADAM17 substrates correlates to recurring cardiovascular event in subjects with atherosclerosis [PDF]

, 2015
Atherosclerosis disease is a leading cause for mortality and morbidity. The narrowing/rupture of a vulnerable atherosclerotic plaque is accountable for acute cardiovascular events.
Cardellini, M, Copetti, M, Di Cola, G, Federici, M, Ippoliti, A, Luzi, A, Menghini, R, Pecchioli, C, Pellegrini, F, Porzio, O, Rizza, S, Romeo, F   +11 more
core   +1 more source

Plaque Vulnerability

Journal of the American College of Cardiology, 2010
Atherosclerosis is a disease of success and excess. The success is our ability to invent the means to provide a vast excess of daily calories and master both the art of French cooking ([1][1]) and the production of fast food ([2][2]). The excess is our inability to curb the appetites for either,
openaire   +2 more sources

Vulnerable Plaque

Journal of the American College of Cardiology, 2015
In their recent perspective, Arbab-Zadeh and Fuster explore the generally accepted concept that atherothrombotic events result from the interaction between systemic factors (inflammation and thrombosis) and local substrates (individual plaques).
Evan D. Muse, Mazen Albaghdadi
openaire   +3 more sources

Modulation of Aging Diseases via RAGE Targets: A Dietary Intervention Review

Advanced Science, EarlyView.
This paper analyzes RAGE ligand‐binding mechanisms and signaling, proposing intervention strategies targeting these interactions. It emphasizes dietary polyphenols, polysaccharides, and terpenoids delivered via functional foods for anti‐aging. These compounds offer long‐term, safe intervention through dietary supplementation, providing dual nutritional
Qian Wu, Jia Yan, Yuyan Zhang, Xiaozhi Ming, Siqi Chen, Zhichao Zou, Nianjie Feng, Jianbo Xiao   +7 more
wiley   +1 more source

Biomarkers in acute coronary syndromes and their role in diabetic patients [PDF]

, 2005
Diabetic patients with acute coronary syndromes are at high risk for cardiovascular complications but risk stratification in these patients remains challenging.
Christopher Heeschen, Heeschen C, James SK, Khaliq A, Luttun A, Mak KH   +5 more
core   +1 more source

Illuminating Tau Aggregates: Multiscale Approaches for Detection, Imaging, and Understanding

Aggregate, EarlyView.
This review presents recent advances in molecular imaging of tauopathies, focusing on tau aggregation mechanisms, structural polymorphism, and imaging strategies. It highlights the development of tau‐selective fluorescent probes and PET tracers and explores emerging techniques such as cryo‐EM and super‐resolution imaging, offering a multiscale ...
Kaustubh R. Bhuskute, Jiayi Fan, Amandeep Kaur   +2 more
wiley   +1 more source

Classification of carotid atherosclerotic plaque components using T2 mapping technique from magnetic resonance imaging

Journal of Associated Medical Sciences, 2014
Introduction: Vulnerable plaque or soft plaque potentially increases risk of stroke. Accurate plaque characterization is a demand for treatments. To date, magnetic resonance imaging (MRI) using multiweighted images, T1 weighted (T1W), T2 weighted (T2E ...
Sranut Chunpenmongkol, Kittichai Wantanajittikul, Kittipan Rerkasem, Charin Ya-in, Suwit Saekho   +4 more
doaj