Results 41 to 50 of about 46,879 (333)

Improving segmentation of calcified and non-calcified plaques on CCTA-CPR scans via masking of the artery wall [PDF]

open access: yesSPIE 12465, Medical Imaging 2023: Computer-Aided Diagnosis, 2022
The presence of plaques in the coronary arteries is a major risk to the patients' life. In particular, non-calcified plaques pose a great challenge, as they are harder to detect and more likely to rupture than calcified plaques. While current deep learning techniques allow precise segmentation of real-life images, the performance in medical images is ...
arxiv   +1 more source

Automated analysis of fibrous cap in intravascular optical coherence tomography images of coronary arteries [PDF]

open access: yesarXiv, 2022
Thin-cap fibroatheroma (TCFA) and plaque rupture have been recognized as the most frequent risk factor for thrombosis and acute coronary syndrome. Intravascular optical coherence tomography (IVOCT) can identify TCFA and assess cap thickness, which provides an opportunity to assess plaque vulnerability.
arxiv  

Optical imaging techniques for vulnerable plaque detection

open access: yesTranslational Biophotonics, 2020
Vulnerable plaque rupture is the most important cause of myocardial infarction and acute coronary syndrome. Therefore, identifying vulnerable plaques is of prime importance, which will in turn aid in the development of treatments to stabilise them ...
Suleiman Eldomi   +4 more
doaj   +1 more source

Comparison of multilayer and single-layer coronary plaque models on stress/strain calculations based on optical coherence tomography images

open access: yesFrontiers in Physiology, 2023
Mechanical stress and strain conditions are closely related to atherosclerotic plaque progression and rupture and have been under intensive investigations in recent years.
Mengde Huang   +12 more
doaj   +1 more source

Wall Shear Stress Analysis in Stenosed Carotid Arteries with Different Shapes of Plaque [PDF]

open access: yesInternational Journal of Computer Applications, Volume 145, No.4, July 2016, 2017
Atherosclerosis is a disease caused due to formation of plaque into the artery. Increase in plaque affects the wall shear stress. The present study is performed to calculate wall shear stress in different geometries of stenosed carotid artery. A 2D model of different geometries is generated using CFD for Non- Newtonian model.
arxiv   +1 more source

The Impact of Coronary Artery Calcification on Long-Term Cardiovascular Outcomes

open access: yesJournal of Interdisciplinary Medicine, 2021
Decades of research and experimental studies have investigated various strategies to prevent acute coronary events. However, significantly efficient preventive methods have not been developed and still remains a challenge to determine if a coronary ...
Mitra Noémi   +5 more
doaj   +1 more source

Imaging Vulnerable Plaque by Ultrasound

open access: yesJournal of the American College of Cardiology, 2006
Diagnostic techniques to identify vulnerable plaques are rapidly evolving. Intravascular ultrasound (IVUS) has the ability to detect and localize plaque as well as quantitate plaque burden. Recent IVUS studies have suggested that patients presenting with acute coronary syndromes have an approximate 25% incidence of additional ruptured plaques in ...
Sotirios Tsimikas   +3 more
openaire   +3 more sources

Sex-specific association between inflammation and endothelial function relevant gene and vulnerable carotid plaque

open access: yesFrontiers in Physiology, 2022
Objectives: We aimed to explore sex-specific association between genes involved in inflammation and endothelial function and vulnerable carotid plaque, a subclinical precursor of ischemic stroke.Methods: Carotid plaque and plaque phenotype were assessed ...
Jie Li   +6 more
doaj   +1 more source

Mechanisms of plaque vulnerability and rupture [PDF]

open access: yesJournal of the American College of Cardiology, 2003
Rupture of atherosclerotic plaque has been identified as the proximate event in the majority of cases of acute ischemic syndromes. Plaque rupture exposes thrombogenic components of the plaque, activating the clotting cascade and promoting thrombus formation.
openaire   +2 more sources

The Aging Substantia Nigra is Characterized by ROS Accumulation Potentially Resulting in Increased Neuroinflammation and Cytoskeletal Remodeling

open access: yesAdvanced Biology, Volume 9, Issue 4, April 2025.
Definition of study groups, including young individuals (n = 7 mean age: 28.7 years), middle aged individuals (n = 14 mean age: 62.3 years) and elderly individuals (n = 14 mean age: 83.9 years). Condensed workflow including sample preparation (sample lysis and tryptic digestion), mass spectrometric measurements and subsequent data and statistical ...
Britta Eggers   +10 more
wiley   +1 more source

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