Results 41 to 50 of about 76,465 (345)

Reduced Necrosis and Content of Apoptotic M1 Macrophages in Advanced Atherosclerotic Plaques of Mice With Macrophage-Specific Loss of Trpc3 [PDF]

, 2017
In previous work we reported that ApoeKO mice transplanted with bone marrow cells deficient in the Transient Receptor Potential Canonical 3 (TRPC3) channel have reduced necrosis and number of apoptotic macrophages in advanced atherosclerotic plaques ...
Birnbaumer, Lutz, Dube, Prabhatchandra R., Solanki, Sumeet, Vazquez, Guillermo   +3 more
core   +1 more source

b-Gamma-glutamyltransferase activity in human vulnerable carotid plaques. [PDF]

, 2014
Objective: The atherosclerotic plaque that is vulnerable to rupture and to superimposed thrombosis is mainly represented by a thin-cap fibroatheroma with or without ulceration/thrombosis and inflammatory infiltrates.
A. Paolicchi, A. Pucci, C. Passino, F. Basolo, M. Emdin, M. Ferrari, M. Franzini, M. Marconi, M. Matteucci, S. Ceragioli   +9 more
core   +1 more source

Computed Tomography Biomarkers of Vulnerable Coronary Plaques

Journal of Interdisciplinary Medicine, 2016
An unstable plaque has a high risk of thrombosis and at the same time for a fast progression of the stenosis degree. Also, “high-risk plaque” and “thrombosis-prone plaque” are used as synonym terms for characterization of a vulnerable plaque. The imaging
Nyulas Tiberiu, Chiţu Monica, Mester András, Jáni Laura, Condrea Sebastian, Opincariu Diana, Kovács István, Benedek Imre, Benedek Theodora   +8 more
doaj   +1 more source

Geographical predisposition influences on the distribution and tissue characterisation of eccentric coronary plaques in non-branching coronary arteries: cross-sectional study of coronary plaques analysed by intravascular ultrasound

Cardiovascular Ultrasound, 2016
Background We investigated the influence of geographical predisposition on the spatial distribution and composition of coronary plaques. Methods Thirty coronary arteries were evaluated.
Hidenori Komiyama, Hitoshi Takano, Shunichi Nakamura, Masamichi Takano, Noritake Hata, Miyauchi Yasushi, Yoshihiko Seino, Kyoichi Mizuno, Wataru Shimizu   +8 more
doaj   +1 more source

Non-invasive MR imaging of inflammation in a patient with both asymptomatic carotid atheroma and an abdominal aortic aneurysm: a case report. [PDF]

, 2007
Inflammation is a recognized risk factor for the vulnerable atherosclerotic plaque. USPIO-enhanced MRI imaging is a promising non-invasive method to identify high-risk atheromatous plaque inflammation in vivo in humans, in which areas of focal signal ...
Gaunt, Michael E, Gillard, Jonathan H, Graves, Martin J, Howarth, Simon PS, Li, Zhi-Yong, Tang, Tjun Y, U-King-Im, Jean-Marie, Walsh, Stewart R   +7 more
core   +2 more sources

The complementary roles of dynamic contrast-enhanced MRI and 18F-fluorodeoxyglucose PET/CT for imaging of carotid atherosclerosis [PDF]

, 2016
Inflammation and neovascularization in vulnerable atherosclerotic plaques are key features for severe clinical events. Dynamic contrast-enhanced (DCE) MRI and FDG PET are two noninvasive imaging techniques capable of quantifying plaque neovascularization
Bucerius, Jan, Calcagno, Claudia, Farkouh, Michael E, Farkouh, Michael E., Fayad, Zahi A, Fayad, Zahi A., Fuster, Valentin, Godbold, James, Izquierdo-Garcia, David, Kallend, David, Mani, Venkatesh, Millon, Antoine, Moshier, Erin, Ramachandran, Sarayu, Rosenbaum, David, Rudd, James H F, Rudd, James H. F., Tawakol, Ahmed, Woodward, Mark   +18 more
core   +1 more source

Comparison of multilayer and single-layer coronary plaque models on stress/strain calculations based on optical coherence tomography images

Frontiers in Physiology, 2023
Mechanical stress and strain conditions are closely related to atherosclerotic plaque progression and rupture and have been under intensive investigations in recent years.
Mengde Huang, Akiko Maehara, Dalin Tang, Dalin Tang, Jian Zhu, Liang Wang, Rui Lv, Yanwen Zhu, Xiaoguo Zhang, Mitsuaki Matsumura, Lijuan Chen, Genshan Ma, Gary S. Mintz   +12 more
doaj   +1 more source

The Use of Biomarkers for the Early Detection of Vulnerable Atherosclerotic Plaques and Vulnerable Patients. A Review

Journal of Cardiovascular Emergencies, 2016
Acute coronary syndromes represent the most severe consequences of atherosclerosis, most often triggered by the rupture of a coronary plaque, which, for various reasons, has become unstable.
Benedek Theodora, Maurovich-Horváth Pál, Ferdinandy Péter, Merkely Béla   +3 more
doaj   +1 more source

Optical imaging techniques for vulnerable plaque detection

Translational Biophotonics, 2020
Vulnerable plaque rupture is the most important cause of myocardial infarction and acute coronary syndrome. Therefore, identifying vulnerable plaques is of prime importance, which will in turn aid in the development of treatments to stabilise them ...
Suleiman Eldomi, Junaid Zafar, Ritasree Sengupta, Faisal Sharif, Haroon Zafar   +4 more
doaj   +1 more source

Ultra-short echo time cardiovascular magnetic resonance of atherosclerotic carotid plaque. [PDF]

, 2010
BACKGROUND: Multi-contrast weighted cardiovascular magnetic resonance (CMR) allows detailed plaque characterisation and assessment of plaque vulnerability.
Boyle, JJ, Chan, CF, Firmin, DN, Gatehouse, P, Keenan, NG, Nielles-Vallespin, S, Pennell, DJ, Sheppard, MN   +7 more
core   +2 more sources