Results 61 to 70 of about 19,845 (173)
Ligation of macrophage Fcγ receptors recapitulates the gene expression pattern of vulnerable human carotid plaques. [PDF]
PLoS ONE, 2011 Stroke is a leading cause of death in the United States. As ∼60% of strokes result from carotid plaque rupture, elucidating the mechanisms that underlie vulnerability is critical for therapeutic intervention.
Michelle R Lennartz +8 more
doaj +1 more source
Vulnerable Carotid Artery Plaques in Asymptomatic Patients—A Narrative Review
The Arab Journal of Interventional Radiology, 2022 Over the last two decades, medical management of carotid artery patients has improved significantly. Most patients remain stable on best medical therapy (BMT), making interventions unnecessary in all patients.
Zia Ur Rehman
doaj +1 more source
Vulnerable Plaque Inside Stent
JACC: Cardiovascular Imaging, 2011 it has been proposed that nonhealing endothelium after percutaneous coronary intervention may allow for insudation of lipids superficial to the stent strut level, especially when the underlying plaque carried a large necrotic core.
Il Suk Sohn +3 more
openaire +3 more sources
A new lipid-structured model to investigate the opposing effects of LDL and HDL on atherosclerotic plaque macrophages [PDF]
arXiv, 2022 Atherosclerotic plaques form in artery walls due to a chronic inflammatory response driven by lipid accumulation. A key component of the inflammatory response is the interaction between monocyte-derived macrophages and extracellular lipid. Although concentrations of low-density lipoprotein (LDL) and high-density lipoprotein (HDL) particles in the blood
arxiv
Multimodal photoacoustic imaging in analytic vulnerability of atherosclerosis
iRADIOLOGY, 2023 Atherosclerosis is a major cause of mortality and morbidity, and rupture can lead to myocardial infarction and stroke. The vulnerability assessment of atherosclerosis plaques is important for providing medical treatment.
Wangting Zhou +4 more
doaj +1 more source
A Two-Phase Model of Early Atherosclerotic Plaque Development with LDL Toxicity Effects [PDF]
arXiv, 2023 Atherosclerosis is a chronic inflammatory cardiovascular disease in which fatty plaque is built inside an artery wall. Early atherosclerotic plaque development is typically characterized by inflammatory tissues primarily consisting of foam cells and macrophages.
arxiv
Carotid Plaque Vulnerability Diagnosis by CTA versus MRA: A Systematic Review
Diagnostics, 2023 Stenosis grade of the carotid arteries has been the primary indicator for risk stratification and surgical treatment of carotid artery disease. Certain characteristics of the carotid plaque render it vulnerable and have been associated with increased ...
Konstantinos Dakis +6 more
doaj +1 more source
MSCT Identification of Vulnerable Plaque
JACC: Cardiovascular Imaging, 2016 Acute myocardial infarction and sudden cardiac death are the first manifestations of coronary artery disease in most patients. Identifying patients at high risk for developing acute coronary syndromes (ACS) is a major challenge for contemporary cardiovascular imaging.
Alexandre Abizaid +6 more
openaire +3 more sources
Vulnerable Plaque, Characteristics, Detection, and Potential Therapies
Journal of Cardiovascular Development and Disease, 2019 Plaque development and rupture are hallmarks of atherosclerotic vascular disease. Despite current therapeutic developments, there is an unmet necessity in the prevention of atherosclerotic vascular disease. It remains a challenge to determine at an early
Anouar Hafiane
doaj +1 more source
Concept of Vulnerable/Unstable Plaque [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2010 Today’s concept of vulnerable plaque has evolved primarily from the early pioneering work uncovering the pivotal role of plaque rupture and coronary thrombosis as the major cause of acute myocardial infarction and sudden cardiac death. Since the first historical description of plaque rupture in 1844, several key studies by leading researchers and ...
Renu Virmani +4 more
openaire +3 more sources