Results 211 to 220 of about 1,072,936 (352)

Mean personal vulnerability population statistic [PDF]

Behaviour Change Intervention Ontology (BCIO)
openalex   +1 more source

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

Allogeneic hematopoietic cell transplantation in vulnerable populations: Advances and perspectives. [PDF]

Chin J Cancer Res
Fan Y, Chen J.
europepmc   +1 more source

Recruitment planning for clinical trials with a vulnerable perinatal adolescent population using the Clinical Trials Transformative Initiative framework and principles of partner and community engagement

, 2021
Abigail Gamble, Bettina M. Beech, Chad Blackshear, Katherine L. Cranston, Sharon J. Herring, Justin B. Moore, Michael A. Welsch   +6 more
openalex   +2 more sources

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

Evacuation and Transportation Barriers Among Vulnerable Populations in Natural Hazard-Related Disasters: A Scoping Review. [PDF]

Int J Environ Res Public Health
Matsuo Y, Kietzman K, Hays RD, Song Y.
europepmc   +1 more source

Assessing the Need for Mobile Application Development in Stunting Prevention Among Vulnerable Populations: A Qualitative Study

Achmad Setya Roswendi, Yayat Suryati, Qury Alifia Nabila, Lina Safarina   +3 more
openalex   +2 more sources

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Erratum: Safety of Remimazolam in Vulnerable Populations [Corrigendum]. [PDF]

Drug Des Devel Ther
europepmc   +1 more source

Video recording as a data collection method in vulnerable populations - methodological and ethical considerations. [PDF]

PEC Innov
Karlsen MW, Sørensen K, Hofset Larsen B, Heyn LG, Gerwing J.   +4 more
europepmc   +1 more source