Results 141 to 150 of about 47,556 (256)

The Cancer Immunotherapy Thromboembolism Assessment: A Novel Score for Predicting Thromboembolic Events in Melanoma Patients Treated With Immune Checkpoint Inhibition

International Journal of Cancer, Volume 159, Issue 5, Page 1337-1344, 1 September 2026.
Although immune checkpoint inhibitors (ICI) have transformed metastatic melanoma treatment, thromboembolic events (TEEs) remain a serious complication. Moreover, existing risk assessment models were developed prior to ICI use and lack clinical validation.
Tim Zell, Julian Kött, Noah Zimmermann, Greta Ancker, Alexander T. Bauer, Daniel J. Smit, Glenn Geidel, Julian C. Gerwers, Thomas Renné, Sebastian A. Wohlfeil, Jochen Utikal, Stefan W. Schneider, Christoffer Gebhardt   +12 more
wiley   +1 more source

Integrative multi‐omics analysis prioritizes DPEP1 as a genetically supported candidate associated with skin cancer risk

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Flowchart of the study design outlining target identification, validation, and subsequent functional and translational characterization. Abstract Background Skin cancer (SC) is among the most prevalent malignancies, yet causal circulating proteins and tractable therapeutic targets remain poorly defined.
Fan Shen, Yongkai Yu, Zongfeng Liao, Liye Mao, Qianyun Wang, Wanju Wang, Yuanhui Liu, Ling Li   +7 more
wiley   +1 more source

Individual Comparative PK Evaluation of Single-dose Octocog Alfa, Rurioctocog Alfa Pegol, and Efanesoctocog Alfa in Adults with Severe Hemophilia A. [PDF]

TH Open
Staber JM, Lissitchkov T, Chan AKC, Wilson AS, Dumont J, Willemze AJ.   +5 more
europepmc   +1 more source

Thromboinflammatory biomarkers in obstetric pathophysiology: Predictive insights into placental insufficiency and feto‐maternal adverse outcomes

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Placental insufficiency is a thromboinflammatory disorder driven by angiogenic imbalance, complement activation, endothelial dysfunction and coagulation dysregulation, leading to microvascular thrombosis, impaired uteroplacental perfusion and adverse maternal and fetal outcomes, including pre‐eclampsia, fetal growth restriction and stillbirth. Abstract
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Plasma small-extracellular vesicles' proteomic signature in neoadjuvant chemotherapy-naïve breast cancer patients. [PDF]

PLoS One
WalyEldeen AA, Mohamed G, Taha SN, Gameel AM, Talat LY, Hassan H, Ibrahim SA.   +6 more
europepmc   +1 more source

Pulsed Electric Field Processing Enhances the Endothelial Bioefficacy of Red Beet (Beta vulgaris L.) Extracts by Restoring Endothelial Nitric Oxide Synthase–Nitric Oxide Signaling in High‐Fat Diet Rats

eFood, Volume 7, Issue 4, August 2026.
Pulsed electric field (PEF) processing qualitatively reshapes the phytochemical profile of red beet extracts, resulting in enhanced endothelial bioefficacy. Compared with conventional extraction, PEF‐treated extracts more effectively restore nitric oxide signaling, suppress endothelial inflammation, and normalize vascular structure in high‐fat diet ...
Eunju Jang, Tae‐Baek Lee, Lisa Tonini, Soobin Choi, YoonA Jeon, Taehyun Kim, Taeyoung Kang, Hyuk‐Joon Choi, Changhwan Ahn   +8 more
wiley   +1 more source

Biology of von Willebrand disease. [PDF]

Blood Adv
Flood VH, Haberichter SL.
europepmc   +1 more source

Bioresorbable Scaffolds for Coronary Arteries: Where Do We Stand Today?

VIEW Medicine, Volume 1, Issue 1, August 2026.
Bioresorbable coronary scaffolds are moving from thick strut pitfalls to thinner, stronger, healing‐oriented designs. Integrating advances in materials, guided implantation with preparation, size, and postdilation steps, and resorption aligned to healing, we synthesize clinical evidence and chart a roadmap toward intelligent, transient platforms ...
Junya Matsuda, Tatsuya Watanabe, Satoshi Yuhara, John M. Kelly, Hirotsugu Kurobe, Toshiharu Shinoka   +5 more
wiley   +1 more source

Retrospective analysis of von willebrand factor and microthrombus formation in septic shock: associations with TTP-like syndrome and sepsis-induced coagulopathy. [PDF]

Am J Clin Exp Immunol
Liu Y, Yue J, Huang Q, Wan L, Zhao W, Ren Z, Han C, Zhang B, Li C, Pan L, Zhang H, Zhang J.   +11 more
europepmc   +1 more source

Climatic Impacts of Large‐Scale Wind Farms in Arid and Semi‐Arid Region in China: A Case Study of the Huitengxile Wind Farm in Inner Mongolia

Wind Energy, Volume 29, Issue 8, August 2026.
ABSTRACT With the rapid expansion of China's wind power industry, the local climatic impacts of large‐scale wind farms, particularly in arid and semi‐arid regions, have attracted increasing attention. This study investigates the effects of the Huitengxile wind farm in Inner Mongolia, which hosts over 1,200 wind turbines, using high‐resolution numerical
Xiashu Su, Entao Yu, Dongwei Liu
wiley   +1 more source