Results 151 to 160 of about 47,556 (256)

HMB-002: a monovalent antibody that elevates circulating VWF and FVIII levels for treatment of von Willebrand disease. [PDF]

Blood Adv
Häger M, Zivkovic M, Gandhi PS, Rasmussen C, Bonvoisin C, Harrison RA, Poulsen E, Huskens D, Roest M, Ferrara F, Naretto A, Renaud L, Olsen OH, Eskesen NO, Holten-Andersen L, Malladi R, Rea CJ, Sørensen B, Urbanus RT, Østergaard H.   +19 more
europepmc   +1 more source

Haemostatic changes and bleeding with anti‐IL‐6 directed therapy in autoimmune diseases

British Journal of Pharmacology, Volume 183, Issue 15, Page 4111-4125, August 2026.
Abstract Anti‐IL‐6 directed therapy, especially tocilizumab (TCZ), is widely used for the treatment of autoimmune diseases such as rheumatoid arthritis, giant cell arteritis and systemic juvenile idiopathic arthritis. Next to being a master regulator of inflammation, IL‐6 also is an important regulator of haemostasis. Although generally well tolerated,
Charlotte D. C. C. van der Heijden, Loes C. Oskam, Lenny van Bon, Chantal P. Rovers   +3 more
wiley   +1 more source

Monovalent antibody treatment of von Willebrand disease. [PDF]

Blood Adv
O'Donnell JS.
europepmc   +1 more source

Microgel‐Based 3D Bioprinting: A Convergent Strategy Integrating Material Design, Jamming Dynamics, and Biological Function

Advanced Healthcare Materials, Volume 15, Issue 25, 3 July 2026.
Microgel‐based 3D printed constructs represent a compelling and versatile innovation for engineering architecturally complex, dynamically remodelable, and biocompatible structures with high structural fidelity and bioactivity. By integrating material design, biofabrication, and biological function, these systems enable the development of adaptive ...
Elena Ghighină, Andreea Ioana Dinu, Jana Ghițman   +2 more
wiley   +1 more source

Clusterin maintains hemostatic equilibrium by stabilizing VWF multimers in plasma.

Blood
Qiao Z, Cao Y, Su J, Lu S, Wei G, Jin S, Ding Q, Sun Y, Huo Y, Dong M, Luo J, Li P.   +11 more
europepmc   +1 more source

Rat models of thrombotic thrombocytopenic purpura reveal crucial role of placental ADAMTS13 in perinatal survival. [PDF]

Blood Adv
Zhang Q, Zheng L, Chai Z, Wu Z, Dominguez EM, Soares MJ, Zheng XL.   +6 more
europepmc   +1 more source

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

Advanced Science, Volume 13, Issue 39, 13 July 2026.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee, Chul‐Gyun Lim, Pothiappan Vairaprakash, Jong‐Min Kim, Jiyoon Kim, Ji‐Young Park, Klaus M. Hahn, Hyunbo Shim, Hae Woong Choi, Tobias S. Ulmer, Soon Jun Hong, Chungho Kim   +11 more
wiley   +1 more source

Type 3 Von Willebrand disease: two clinical cases of a rare disorder. [PDF]

Oxf Med Case Reports
Belcadi Abassi K, Larbi Ouassou K, Radi A, Laaraje A, Babour S, Ait Hmadouch S, Hassani A, Khorassani MEL, Abilkassem R.   +8 more
europepmc   +1 more source

The need for dried plasma—Still a national issue: Where are we and recommendations

Transfusion, EarlyView.
Anthony E. Pusateri, Shibani Pati, Toby A. Silverman, Roman Dudaryk, Joseph F. Rappold, Lisa Buckley, Andrew P. Cap, Jose A. Cancelas, Laurence M. Corash, G. Michael Fitzpatrick, Michael Ganio, Adam Gerber, Richard Gonzales, Jennifer M. Gurney, Ernest E. Moore, Hunter B. Moore, Vijay Nair, Michael Policastro, Travis M. Polk, Jeffrey W. Shupp, Jason L. Sperry, Ralph R. Vassallo, Therese A. West, John B. Holcomb, Lester Martinez‐Lopez   +24 more
wiley   +1 more source

Lyophilized Synthetic Platelets: In Vitro Characterization and In Vivo Evaluation in Mouse Thrombocytopenia Model

Advanced Science, Volume 13, Issue 38, 9 July 2026.
ABSTRACT Platelet transfusions to treat bleeding complications use donor‐derived platelets stored at room‐temperature, that have a shelf‐life of only 5–7 days due to bacterial contamination risks. Cold‐stored and freeze‐dried platelets are being investigated for extending shelf‐life, but these still have the inherent challenge of donor‐dependency.
Ujjal Didar Singh Sekhon, Dante Disharoon, Shrijal S. Desai, Baylee Traylor, Emily Gahagan, Emma Quill, Kristin Aldridge, Norman F. Luc, Sonali Rohiwal, Shruti Raghunathan, Rebecca Ahn, Sana Syed, Alexander Dornback, Bipin Chakravarthy Paruchuri, Andrew Ditto, Susan M. Shea, Philip C. Spinella, Matthew D. Neal, Michael A. Bruckman, Christa L. Pawlowski, Anirban Sen Gupta   +20 more
wiley   +1 more source