Results 161 to 170 of about 47,556 (256)
A three-dimensional shear dependent continuum model of platelet aggregation under flow. [PDF]
PLoS Comput BiolMontgomery D +6 more
europepmc +1 more source
Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.Genomic SEM of five ASCVD traits in > 3.8 million individuals identified 347 risk variants, including 19 novel loci. Integrating fine‐mapping and TWAS prioritized causal genes and revealed endothelial cell enrichment in vascular tissues. AI modelling shows the DCLRE1B mutation destabilizes the protein, impairing DNA repair and transcription.
Liwan Fu +4 more
wiley +1 more source
Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.A transcriptome‐based succinylation score (SS) stratifies prostate cancer by prognosis, immune contexture, and chemotherapy sensitivity. KAT2A is enriched in low‐SS, chemoresistant tumours and promotes resistance by succinylating PIK3R2. KAT2A‐mediated succinylation competitively inhibits PIK3R2 ubiquitination, stabilising PIK3R2 and driving ...
Antao Dong +6 more
wiley +1 more source
Assessing the Impact of the 2021 VWD Guidelines on the Diagnosis/Management of Low VWF Patients. [PDF]
HaemophiliaDong M +4 more
europepmc +1 more source
Extracellular Vesicles in Head and Neck Cancer—A Systematic Review
Journal of Extracellular Biology, Volume 5, Issue 7, July 2026.ABSTRACT Head and neck cancer (HNC) is among the top ten malignancies worldwide and is associated with high morbidity and mortality. Oral potentially malignant disorders (OPMDs) predispose to certain HNCs. Recent studies suggest emerging roles of extracellular vesicles (EVs) in malignant transformation and provide potential in the management of HNC ...
Abdallah Swaid +5 more
wiley +1 more source
Exposure-response relation for vibration-induced white finger: influence of different estimates of daily exposure time. [PDF]
Int Arch Occup Environ HealthScholz MF, Brammer AJ, Marburg S.
europepmc +1 more source
Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions
MedComm, Volume 7, Issue 7, July 2026.Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An +4 more
wiley +1 more source
MedComm, Volume 7, Issue 7, July 2026.Concurrent chemoradiotherapy plus immunotherapy (CICRT) promotes tumor microenvironment remodeling in locally advanced cervical cancer to enhance antitumor immunity. It reduces regulatory T cells and mitigates CD8+ T‐cell exhaustion while reprogramming macrophages toward a pro‐inflammatory phenotype. Furthermore, CICRT upregulates MHC‐II expression and
Yuhan Sheng +7 more
wiley +1 more source
Primary Pulmonary Angiosarcoma: Case Report and Literature Review
Respirology Case Reports, Volume 14, Issue 7, July 2026.We present a case of primary pulmonary angiosarcoma with widespread metastatic disease, initially presenting with nonspecific respiratory symptoms and diagnostic uncertainty, ultimately diagnosed via robotic navigational bronchoscopy. This case highlights the challenges in early recognition and the potential role of advanced bronchoscopic techniques in
Shafaq Jawed, Sarva Sivatej
wiley +1 more source