Results 211 to 220 of about 69,458 (313)

ADAMTS13 reduces VWF‐mediated acute inflammation following focal cerebral ischemia in mice [PDF]

open access: bronze, 2012
Mohammad Moshahid Khan   +3 more
openalex   +1 more source

Development and Validation of a Liquid Chromatography High‐Resolution Mass Spectrometry Method for Blood Desmopressin Quantification and Its Application in Hemophilia A Patients

open access: yesRapid Communications in Mass Spectrometry, Volume 39, Issue 18, 30 September 2025.
ABSTRACT Desmopressin (DDAVP), which indirectly increases Coagulation Factor VIII concentrations in the blood, is a common treatment for bleeding disorders such as von Willebrand disease or hemophilia A. However, DDAVP exhibits significant variability in response due to interindividual differences in pharmacokinetics.
Sophie Hodin   +7 more
wiley   +1 more source

Inhibition of autotaxin activity with IOA‐289 decreases fibrosis in mouse E0771 breast tumors

open access: yesInternational Journal of Cancer, Volume 157, Issue 6, Page 1205-1217, 15 September 2025.
What's new? Lysophosphatidate is one of the critical mediators of fibrosis formation in the tumor microenvironment, which hinders immune surveillance and therapy. Building on their previous finding that blocking lysophosphatidate production with the autotaxin inhibitor, IOA‐289 decreased tumor growth by approximately 60%, here the authors show that ...
Xiaoyun Tang   +4 more
wiley   +1 more source

Acquired von Willebrand syndrome secondary to monoclonal gammopathy: a single-center case series. [PDF]

open access: yesTher Adv Hematol
Van Thillo Q   +11 more
europepmc   +1 more source

Reperfusion of cerebral artery thrombosis by the GPIb–VWF blockade with the Nanobody ALX-0081 reduces brain infarct size in guinea pigs [PDF]

open access: bronze, 2013
Stefania Momi   +5 more
openalex   +1 more source

Evaluation of Testican‐1 as a Sepsis Biomarker in Pyometra Cats

open access: yesVeterinary Medicine and Science, Volume 11, Issue 5, September 2025.
This study evaluated whether Testican‐1 is a potential biomarker for feline sepsis using a model for natural sepsis in cases of pyometra, a common gynaecological disease in cats. The study concluded that Testican‐1 is an important step in the evaluation of feline sepsis.
Ömer Yaprakci, Tuğra Akkuş
wiley   +1 more source

Type 2 diabetes and depression via microvascular dysfunction, neurodegeneration, inflammation, advanced glycation end products (AGEs), and arterial stiffness

open access: yesDiabetes, Obesity and Metabolism, Volume 27, Issue 9, Page 4847-4858, September 2025.
Abstract Aims Type 2 diabetes increases the risk of depression, but the mechanisms underlying this association are incompletely understood. We investigated whether microvascular dysfunction, neurodegeneration, low‐grade inflammation, advanced glycation end products (AGEs) and arterial stiffness, pathologies that are more common in diabetes, explain, or
Indra L. M. Steens   +10 more
wiley   +1 more source

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