Results 221 to 230 of about 69,458 (313)

Role of Gut‐Derived Endotoxins in Porto‐Sinusoidal Vascular Disorder: Comparison Between patients with and without portal hypertension

open access: yesLiver International, Volume 45, Issue 9, September 2025.
ABSTRACT Background Etiopathogenesis of porto‐sinusoidal vascular disorder (PSVD) is poorly known. The present study aimed to investigate alterations in gut barrier, bacterial translocation, and pro‐aggregating/pro‐coagulant state and their relationship with liver injury in patients with PSVD without portal hypertension (PH−) in comparison with PSVD ...
Diletta Overi   +18 more
wiley   +1 more source

Single‐Cell Transcriptomic Profiling of Brain Cells in Newborn Rats Following Hypoxic Ischemic Encephalopathy

open access: yesThe FASEB Journal, Volume 39, Issue 16, 31 August 2025.
This study represents the first scRNA‐seq investigation revealing cellular heterogeneity during the hyperacute (3 h), acute (2 days), and subacute (7 days) phases of neonatal hypoxic–ischemic encephalopathy (HIE). ABSTRACT Neonatal hypoxic–ischemic encephalopathy (HIE) is a severe neurological condition associated with high rates of mortality or long ...
Xianbo Chen, Xiaohong Tao, Jingyu Wang
wiley   +1 more source

Silencing of the von Willebrand factor gene in proatherothrombotic APOE∗3-Leiden.CETP transgenic mice

open access: yesResearch and Practice in Thrombosis and Haemostasis
Background: Elevated von Willebrand factor (VWF) levels correlate with higher risk of atherosclerosis-related arterial thrombosis (atherothrombosis). Silencing the VWF gene via small-interfering RNAs (siRNAs) could mitigate this risk.
Yvonne K. Jongejan   +9 more
doaj  

Red Blood Cell‐Induced Bacterial Margination Improves Microbial Hemoadsorption on Engineered Cell‐Depleted Thrombi, Restoring Severe Bacteremia in Rats

open access: yesAdvanced Science, Volume 12, Issue 29, August 7, 2025.
A highly efficient extracorporeal device for treating bacteremia is developed by integrating microfluidic bacterial margination and engineered cell‐depleted thrombi strategically constructed in the device. The rodent models, severely infected with antibiotic‐resistant bacteria, recover from bacteremia after two subsequent extracorporeal blood ...
Bong Hwan Jang   +4 more
wiley   +1 more source

Thrombocytosis and bleeding in myeloproliferative neoplasms: exploring clinical diversity and risk of acquired von Willebrand syndrome-insights from a UK center. [PDF]

open access: yesRes Pract Thromb Haemost
Simini G   +8 more
europepmc   +1 more source

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