Results 281 to 290 of about 104,334 (371)

Decoding the Cellular Heterogeneity and Malignant Progression of Human Penile Squamous Cell Carcinoma by Single‐Cell RNA Sequencing

open access: yesAdvanced Science, Volume 13, Issue 14, 9 March 2026.
Single‐cell transcriptomic and functional analyses identify SEMA3C as a key regulator of tumor progression and tumor microenvironment remodeling in penile squamous cell carcinoma. SEMA3C promotes epithelial–mesenchymal transition, tumor growth, and invasion while shaping an immunosuppressive microenvironment, highlighting its potential as a prognostic ...
Xiheng Hu   +21 more
wiley   +1 more source

Mutations in the D′D3 region of VWF traditionally associated with type 1 VWD lead to quantitative and qualitative deficiencies of VWF

open access: green, 2016
Tara C. White‐Adams   +4 more
openalex   +2 more sources

Immune Predictors of Radiotherapy Outcomes in Cervical Cancer

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
This study reveals dynamic immune remodeling in cervical cancer following radiotherapy. Single‐cell analysis identifies the C3/C3AR1 axis as a central mediator of epithelial–myeloid crosstalk, whose inhibition reduces treatment efficacy in mice. Guided by these insights, the eight‐feature machine‐learning model: Cervical Cancer Radiotherapy Immune ...
Linghao Wang   +8 more
wiley   +1 more source

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng   +9 more
wiley   +1 more source

Developing an artificial intelligence-generated peptide targeting platelet-type von Willebrand disease. [PDF]

open access: yesBlood Adv
Kazmirchuk TDD   +12 more
europepmc   +1 more source

Common and rare von Willebrand factor (VWF) coding variants, VWF levels, and factor VIII levels in African Americans: the NHLBI Exome Sequencing Project.

open access: yesBlood, 2013
J. Johnsen   +18 more
semanticscholar   +1 more source

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