Results 91 to 100 of about 252,763 (309)
Phenotyping of Rare CFTR Mutations Reveals Distinct Trafficking and Functional Defects
Cells, 2020 Background. The most common CFTR mutation, F508del, presents with multiple cellular defects. However, the possible multiple defects caused by many rarer CFTR mutations are not well studied.
Marjolein Ensinck +9 more
doaj +1 more source
, 1999 Abstract : O-ethyl-S-(diisopropylaminoethly) methyl phosphonothiolate (VX) vapor pressure has been measured using a modified ASTM method in which a carrier gas was slowly passed over the liquid phase, and the saturated effluent was analyzed. Data measured in the current work has extended the low end of the range of measured VX vapor pressures from 30 ...
David E. Tevault +3 more
openaire +1 more source
Advanced Science, EarlyView.Single‐cell profiling across bone marrow, spleen, mesenteric lymph, and blood in rhesus monkeys reveals organ Immunosenescence. GZMB rises with age, particularly in cytotoxic and terminally exhausted CD8+ T cells, and BHLHE40 emerges as a key transcription factor enriched across multiple CD8+ subsets, regulating pro‐inflammatory and exhaustion‐related ...
Shengnan Wang +10 more
wiley +1 more source
JCI Insight, 2020 Based on its clinical benefits, Trikafta — the combination of folding correctors VX-661 (tezacaftor), VX-445 (elexacaftor), and the gating potentiator VX-770 (ivacaftor) — was FDA approved for treatment of patients with cystic fibrosis (CF) carrying ...
Guido Veit +9 more
doaj +1 more source
Frontiers in Veterinary Science, 2023 IntroductionDrug-sensitive live coccidiosis vaccines have been used to control coccidiosis and renew drug sensitivity in commercial chicken operations.
Carolina Trujillo-Peralta +12 more
doaj +1 more source
On one-dimensional models for hydrodynamics [PDF]
, 2006 To date it has not been possible to prove whether or not the three-dimensional incompressible Euler equations develop singular behaviour in finite time.
Baker +29 more
core +2 more sources
Miniature Robotic Swimmer with Precise 2D Motion Control via Acoustic Vortex‐Induced Propulsion
Advanced Science, EarlyView.In this work, a miniature robotic swimmer achieves precise 2D motion using sound waves with customized 3D‐printed lenses. Localized acoustic vortices drive both translation and rotation of the swimmer without mechanical parts. This contactless approach offers a novel route to controlled micro‐scale movement, with promising applications in biomedical ...
Chadi Ellouzi +6 more
wiley +1 more source
Primordial gravitational waves and the collapse of the wave function [PDF]
, 2015 "The self-induced collapse hypothesis" was introduced by D. Sudarsky and collaborators to explain the origin of cosmic structure from a perfect isotropic and homogeneous universe during the inflationary regime.
Kraiselburd, Lucila +2 more
core +2 more sources
Advanced Science, EarlyView.A comprehensive technology platform enables high‐fidelity, volumetric MALDI imaging of 3D cell cultures by integrating custom embedding molds, a semi‐automated computational framework for 3D reconstruction, voxel‐instead of pixel‐based biomarker discovery, and immersive mixed reality data exploration.
Stefania Alexandra Iakab +16 more
wiley +1 more source
Frontiers in Molecular Biosciences, 2021 Cystic fibrosis transmembrane conductance regulator (CFTR) modulators have transformed the treatment of cystic fibrosis (CF) by targeting the basis of the disease.
Eyleen de Poel +10 more
doaj +1 more source