Results 61 to 70 of about 243,296 (232)
Phenotyping of Rare CFTR Mutations Reveals Distinct Trafficking and Functional Defects
Cells, 2020 Background. The most common CFTR mutation, F508del, presents with multiple cellular defects. However, the possible multiple defects caused by many rarer CFTR mutations are not well studied.
Marjolein Ensinck +9 more
doaj +1 more source
Rescue of Mutant CFTR Trafficking Defect by the Investigational Compound MCG1516A
Cells, 2022 Although some therapeutic progress has been achieved in developing small molecules that correct F508del-CFTR defects, the mechanism of action (MoA) of these compounds remain poorly elucidated.
Miquéias Lopes-Pacheco +9 more
doaj +1 more source
, 1999 Abstract : O-ethyl-S-(diisopropylaminoethly) methyl phosphonothiolate (VX) vapor pressure has been measured using a modified ASTM method in which a carrier gas was slowly passed over the liquid phase, and the saturated effluent was analyzed. Data measured in the current work has extended the low end of the range of measured VX vapor pressures from 30 ...
David E. Tevault +3 more
openaire +1 more source
Impedance‐Matched High‐Overtone Thickness‐Shear Bulk Acoustic Resonators With Scalable Mode Volume
Advanced Science, EarlyView.A bottom‐electrode‐free high‐overtone bulk acoustic resonator is achieved by lateral excitation of antisymmetric thickness‐shear modes on a lithium‐niobate‐on‐silicon platform. Planar electrode geometry eliminates conventional loading along the resonance path and confines acoustic energy within the electrode gap.
Zi‐Dong Zhang +7 more
wiley +1 more source
JCI Insight, 2020 Based on its clinical benefits, Trikafta — the combination of folding correctors VX-661 (tezacaftor), VX-445 (elexacaftor), and the gating potentiator VX-770 (ivacaftor) — was FDA approved for treatment of patients with cystic fibrosis (CF) carrying ...
Guido Veit +9 more
doaj +1 more source
Frontiers in Veterinary Science, 2023 IntroductionDrug-sensitive live coccidiosis vaccines have been used to control coccidiosis and renew drug sensitivity in commercial chicken operations.
Carolina Trujillo-Peralta +12 more
doaj +1 more source
SPICE‐Compatible Compact Modeling of Cuprate‐Based Memristors Across a Wide Temperature Range
Advanced Electronic Materials, EarlyView.A physics‐guided compact model for YBCO memristors is introduced, incorporating carrier trapping, field‐induced detrapping, and a differential balance equation to describe their switching dynamics. The model is compared with experiments and implemented in LTspice, allowing realistic circuit‐level simulations.
Thomas Günkel +6 more
wiley +1 more source
Experimental study of granular surface flows via a fast camera: a continuous description [PDF]
, 2001 Depth averaged conservation equations are written for granular surface flows. Their application to the study of steady surface flows in a rotating drum allows to find experimentally the constitutive relations needed to close these equations from ...
Bouchaud J.-Ph +5 more
core +4 more sources
Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.It is a fact that slippage causes tracking errors in both longitudinal and lateral directions which results to have less travel distance in tracking a reference trajectory. Less travel distance means having energy loss of the battery and carrying loads less than planned.
Gokhan Bayar +2 more
wiley +1 more source
Hybrid stochastic kinetic description of two-dimensional traffic dynamics [PDF]
, 2017 In this work we present a two-dimensional kinetic traffic model which takes into account speed changes both when vehicles interact along the road lanes and when they change lane.
Herty, Michael +3 more
core +2 more sources