Results 51 to 60 of about 243,296 (232)

P38 MAP kinase inhibitors as potential therapeutics for the treatment of joint degeneration and pain associated with osteoarthritis [PDF]

, 2008
Background Evaluate the potential role of p38 inhibitors for the treatment of osteoarthritis using an animal model of joint degeneration (iodoacetate-induced arthritis) and a pain model (Hargraeves assay).
Kimberly K Brown, Sandra A Heitmeyer, Erin B Hookfin, Lily Hsieh, Maria Buchalova, Yetunde O Taiwo, Michael J Janusz   +6 more
core   +1 more source

P38 mitogen activated protein kinase inhibitor improves platelet in vitro parameters and in vivo survival in a SCID mouse model of transfusion for platelets stored at cold or temperature cycled conditions for 14 days.

PLoS ONE, 2021
Platelets for transfusion are stored at room temperature (20-24°C) up to 7 days but decline in biochemical and morphological parameters during storage and can support bacterial proliferation.
Andrey Skripchenko, Monique P Gelderman, Jaroslav G Vostal   +2 more
doaj   +1 more source

Genetic parameters and genomic regions associated with piglet response to vaccination for porcine reproductive and respiratory syndrome (PRRS) virus and co-infection with PRRS virus and porcine circovirus type 2b (PCV2b) [PDF]

, 2016
Citation: Dunkelberger, J. R., Serao, N. V. L., Kerrigan, M. A., Lunney, J. K., Rowland, R. R. R., & Dekkers, J. C. M. (2016). Genetic parameters and genomic regions associated with piglet response to vaccination for porcine reproductive and respiratory ...
Dekkers, J. C. M., Dunkelberger, J. R., Kerrigan, M. A., Lunney, J. K., Rowland, Raymond R., Serao, N. V. L.   +5 more
core   +1 more source

Polymer Network Modified Perovskite for High‐Performance Pure Blue Light‐Emitting Diodes

Advanced Functional Materials, EarlyView.
A polymer network of poly(4‐vinylphenol) (PVPh) is introduced to improve pure blue perovskite light‐emitting diodes. PVPh effectively passivates defects, enhances film morphology, reduces lattice strain, and suppresses ion migration. These effects lead to record device performance, achieving 9.82% external quantum efficiency and stable blue emission at
Zhongkai Yu, Jiawei Hong, Jiaxin Song, Zihao Ren, Ke Zhou, Shengnan Liu, Minhui Yu, Yue Xu, Minjeong Ha, Yongbin Hua, Baodan Zhao, Bo Ram Lee   +11 more
wiley   +1 more source

High Pressure Densification Investigation of Li3PS4 and Li6PS5Cl Solid Electrolytes using Combine X‐Ray Diffraction, X‐Ray Absorption Tomography and Ionic Measurement

Advanced Functional Materials, EarlyView.
We used multiple analytical techniques at the Psiché beamline, Synchrotron Soleil, and at D20 instrument in Institut Laue Langevin, to study the densification of thiophosphate solid electrolytes Li3PS4 and Li6PS5Cl. Our combined X‐ray diffraction, absorption tomography, absorption density, neutron power diffraction, and ionic conductivity analyses ...
Oskar Thompson, Ove Korjus, Adrien Fauchier‐Magnan, Clément Albin, Sergio F. Mayer, Emmanuelle Suard, Thomas Hansen, Laura Henry, Nicolas Guignot, Vittoria Pischedda, Sylvie Le Floch, Claire Villevieille   +11 more
wiley   +1 more source

VX toxicity in the Göttingen minipig [PDF]

Toxicology Letters, 2016
The present experiments determined the intramuscular LD50 of VX in male Göttingen minipigs at two stages of development. In pubertal animals (115 days old), the LD50 of VX was indeterminate, but approximated 33.3μg/kg. However, in sexually mature animals (152 days old), the LD50 was estimated to be only 17.4μg/kg.
Jeffrey L, Langston, Todd M, Myers
openaire   +2 more sources

Bioengineered 3D hPSC‐Cholangiocyte Ducts With Physiological Signals for Biliary Disease Modeling

Advanced Healthcare Materials, EarlyView.
Tian and colleagues generated a bioengineered bile duct from human pluripotent stem cell (hPSC)‐derived intrahepatic cholangiocytes within a high‐throughput, 384‐well platform to systematically examine the influence of biliary physiological signals including fluid flow, stromal cells and bile acids, and models intrahepatic biliary disease progression ...
Britney Tian, Mina Ogawa, Manami Kondo, Gabrielle Langeveld, Ling Jun Huan, Feng Zhang, Andrew Hollinger, Sara Deir, Christine Bear, Boyang Zhang, Shinichiro Ogawa   +10 more
wiley   +1 more source

Photocatalytic oxidation of VX-simulation substance

Water Science and Technology, 2007
Experimental studies of photocatalytic oxidation (PCO) of VX-gas simulation substance cysteamine-S-phosphate sodium salt (NaHPO3S–CH2–CH2–NH2, CPSS) at various initial concentrations and pH were undertaken. PCO ultimately resulted in complete mineralisation of CPSS.
Lyon, Celine, Rima, G., Kozlova, E., Vorontsov, A., Preis, S.   +4 more
openaire   +3 more sources

Physical Implementation of Optical Material‐Based Neural Networks Processing Enabled by Long‐Persistent Luminescence

Advanced Science, EarlyView.
This study reports on the physical implementation of optical material‐based neural processing using long‐persistent luminescence as memory‐retention and nonlinear optical material. The system performs optical‐domain preprocessing with opto‐electronic interfaces for stimulus delivery and readout, enabling real‐time demonstrations including Pong gameplay
Sangwon Wi, Yunsang Lee
wiley   +1 more source

Female rats are less susceptible during puberty to the lethal effects of percutaneous exposure to VX

Toxicology Reports, 2016
Nerve agents with low volatility such as VX are primarily absorbed through the skin when released during combat or a terrorist attack. The barrier function of the stratum corneum may be compromised during certain stages of development, allowing VX to ...
Linnzi K.M. Wright, Robyn B. Lee, Edward D. Clarkson, Lucille A. Lumley   +3 more
doaj   +1 more source