Results 111 to 120 of about 7,945,193 (294)
An exact, unified distributional characterization of statistics used to test linear hypotheses in simple regression models [PDF]
The Wald, likelihood ratio and Lagrange multiplier test statistics are commonly used to test linear restrictions in regression models. It is shown that for testing these restrictions in the classical regression model, the exact densities of these test ...
Parker, Thomas
core
Immune Biomarkers of Islet Transplant Rejection Revealed by Synthetic Immunological Niche
Advanced Science, EarlyView.A subcutaneous synthetic immunological niche (IN) enables serial, minimally invasive monitoring of immune responses after islet transplantation. Flow cytometry and transcriptomic profiling of the IN reveal immune‐cell programs associated with graft acceptance and distinct types of rejection.
Jyotirmoy Roy +8 more
wiley +1 more source
Backtesting expectile: Disentangling unconditional coverage and independence properties
Risk SciencesUnder current regulations, financial institutions are required to estimate the daily Value-at-Risk (VaR) or Expected Shortfall (ES) of their trading positions. Despite being widely studied and adopted, both risk measures have theoretical limitations: VaR
Jesus Armando de Ita Solis +3 more
doaj +1 more source
Advanced Science, EarlyView.Based on a multi‐omics cohort of 2002 individuals comprising high‐depth whole‐genome and metagenomic sequencing data, blood metabolites, and detailed questionnaires, we identified 138 859 high‐confidence SVs, uncovering 36 significant SV–microbiome associations and 48 SV–blood metabolite associations.
Qun Zhou +13 more
wiley +1 more source
Weak Change Detection: A Review
MathematicsThis article provides a selective review of offline change-point detection methods, with a particular emphasis on weak change-points. The study of such weak changes plays a central role in establishing the asymptotic properties of test statistics ...
Fatma Aouissaoui, Joseph Ngatchou-Wandji
doaj +1 more source
Advanced Science, EarlyView.Combined inhibition of the WDR5 WIN pocket and HDAC activity converts SAHA‐induced hyperacetylation into a promoter state with reduced WDR5–COMPASS association and H3K4me3. MYC/E2F‐linked nascent transcription and biosynthetic recovery are suppressed, while apoptosis and senescence‐like features increase, resulting in sustained growth inhibition in ...
Jintian Song +8 more
wiley +1 more source
Australia and New Zealand CER Agreement and Breakpoints in Bilateral Trade: An Application of the Wald-type Test [PDF]
This paper investigates the impact of the Australia-New Zealand Closer Economic Relations (CER) Trade Agreement on bilateral trade of each member country by using historical time series data before and after the implementation of the CER.
Jayanthakumaran, Kankesu +1 more
core
Advanced Science, EarlyView.Circulating cell‐free mitochondrial DNA provides a robust, noninvasive platform for early detection and histological subtyping of esophageal cancer. This large multi‐center study validates consistently high accuracy across ethnically and geographically diverse cohorts, demonstrating strong potential to transform clinical management. ABSTRACT Esophageal
Yue Liu +15 more
wiley +1 more source
Joint significance test results of LM, LR and Wald.
Joint significance test results of LM, LR and Wald.
Hongjun Jing (17965523) +2 more
core +1 more source
Advanced Science, EarlyView.This study maps how Epstein–Barr virus reshapes the cellular ecosystem of nasopharyngeal carcinoma. It identifies SPP1+ macrophages as partners of stemness‐associated tumor cells and dysfunctional T cells, links tumor‐derived MIF to macrophage recruitment and programming, and shows that macrophage‐derived SPP1 promotes tumorsphere formation and impairs
Guo‐Ying Liu +15 more
wiley +1 more source