Results 1 to 10 of about 178,927 (241)

Mechanistically informed machine learning links non-canonical TCA cycle activity to Warburg metabolism and hallmarks of malignancy. [PDF]

PLoS Comput Biol
Lin L, Lapi F, Galuzzi BG, Vanoni M, Alberghina L, Damiani C.   +5 more
europepmc   +2 more sources

Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer’s disease [PDF]

Cell Metabolism, 2022
Larissa Traxler, Joseph R. Herdy, Davide Stefanoni, Sophie Eichhorner, Silvia Pelucchi, Attila Szücs, Alice Santagostino, Yongsung Kim, Ravi Kant Agarwal, Johannes C. M. Schlachetzki, Christopher K. Glass, Jessica Lagerwall, Douglas Galasko, Fred H. Gage, Angelo D’Alessandro, Jérôme Mertens   +15 more
openalex   +2 more sources

The Warburg Effect: How Does it Benefit Cancer Cells?

TIBS -Trends in Biochemical Sciences. Regular ed, 2016
Maria V. Liberti, Jason W. Locasale
openalex   +2 more sources

Apostles of Good Taste? The use and perception of plaster casts in the Enlightenment [PDF]

Journal of Art Historiography, 2021
In his ‘Treatise on the Capacity for Sensitivity to the Beautiful in Art …’ Winckelmann compares the feeling of the beautiful in art with liquid plaster poured over the head of the Apollo.
Eckart Marchand
doaj   +1 more source

High-sensitive nascent transcript sequencing reveals BRD4-specific control of widespread enhancer and target gene transcription

Nature Communications, 2023
Gene transcription by RNA polymerase II (Pol II) is under control of promoters and distal regulatory elements known as enhancers. Enhancers are themselves transcribed by Pol II correlating with their activity.
Annkatrin Bressin, Olga Jasnovidova, Mirjam Arnold, Elisabeth Altendorfer, Filip Trajkovski, Thomas A. Kratz, Joanna E. Handzlik, Denes Hnisz, Andreas Mayer   +8 more
doaj   +1 more source

CasTuner is a degron and CRISPR/Cas-based toolkit for analog tuning of endogenous gene expression

Nature Communications, 2023
Certain cellular processes are dose-dependent, requiring specific quantities or stoichiometries of gene products, as exemplified by haploinsufficiency and sex-chromosome dosage compensation.
Gemma Noviello, Rutger A. F. Gjaltema, Edda G. Schulz   +2 more
doaj   +1 more source

Identification of X-chromosomal genes that drive sex differences in embryonic stem cells through a hierarchical CRISPR screening approach

Genome Biology, 2021
Background X-chromosomal genes contribute to sex differences, in particular during early development, when both X chromosomes are active in females.
Oriana Genolet, Anna A. Monaco, Ilona Dunkel, Michael Boettcher, Edda G. Schulz   +4 more
doaj   +1 more source

Studying gestures in art [PDF]

Journal of Art Historiography, 2021
In 1887, when art history was concerned with aethetics and the study of individual artist, Lange, like Warburg after him, encouraged the discussion of broader issues of representation, positioning his study of the representation of a human gesture at the
Eckart Marchand
doaj   +1 more source

Estimation of Battery Separator Area, Cell Thickness and Diffusion Coefficient Based on Non-Ideal Liquid-Phase Diffusion Modeling

Energies, 2020
The aim of this work is to present a fast and in situ diffusion modeling technique to extract essential electrochemical parameters from liquid-phase diffusion which can be used to implement a realistic battery in a pseudo-2D finite element modeling ...
Bence Csomós, Dénes Fodor, István Vajda   +2 more
doaj   +1 more source

When the lens is too wide: The political consequences of the visual dehumanization of refugees

Humanities & Social Sciences Communications, 2021
Photojournalistic images shape our understanding of sociopolitical events. How humans are depicted in images may have far-reaching consequences for our attitudes towards them.
Ruben T. Azevedo, Sophie De Beukelaer, Isla L. Jones, Lou Safra, Manos Tsakiris   +4 more
doaj   +1 more source