Results 21 to 30 of about 167,167 (358)

CircFOXK2 promotes hepatocellular carcinoma progression and leads to a poor clinical prognosis via regulating the Warburg effect

Journal of experimental & clinical cancer research : CR, 2023
Background The Warburg effect is well-established to be essential for tumor progression and accounts for the poor clinical outcomes of hepatocellular carcinoma (HCC) patients.
Jun Zheng, Xijing Yan, Tongyu Lu, Wen Song, Yang Li, Jinliang Liang, Jiebin Zhang, Jianye Cai, Xin Sui, Jiaqi Xiao, Haitian Chen, Gui-huo Chen, Qi Zhang, Yubin Liu, Yang Yang, Kanghong Zheng, Z. Pan   +16 more
semanticscholar   +1 more source

Revisiting the Warburg effect: historical dogma versus current understanding

Journal of Physiology, 2020
Contrary to Warburg's original thesis, accelerated aerobic glycolysis is not a primary, permanent and universal consequence of dysfunctional or impaired mitochondria compensating for poor ATP yield per mole of glucose.
P. Vaupel, G. Multhoff
semanticscholar   +1 more source

Interferon-γ regulates immunosuppression in septic mice by promoting the Warburg effect through the PI3K/AKT/mTOR pathway

Molecular Medicine, 2023
Background The main cause of high mortality from sepsis is that immunosuppression leads to life-threatening organ dysfunction, and reversing immunosuppression is key to sepsis treatment. Interferon γ (IFNγ) is a potential therapy for immunosuppression of
Xueyan Fu, Yu Wang
semanticscholar   +1 more source

Non-political anger shifts political preferences towards stronger leaders

Scientific Reports, 2022
Past research has shown that anger is associated with support for confrontational and punitive responses during crises, and notably with the endorsement of authoritarian ideologies.
Klaudia B. Ambroziak, Lou Safra, Manos Tsakiris   +2 more
doaj   +1 more source

'Reverse Warburg effect' of cancer‑associated fibroblasts (Review).

International Journal of Oncology, 2022
Metabolic reprogramming is one of the main characteristics of malignant tumors. The metabolic reprogramming of tumors is not only related to the characteristics of cancer cells, but also closely related to the tumor microenvironment (TME).
Lin Liang, Wentao Li, Xin Li, Xi Jin, Q. Liao, Yanling Li, Yanhong Zhou   +6 more
semanticscholar   +1 more source

A Philosopher of Primary Processes – Blumenberg’s Anthropological-Aesthetic Project

Profil, 2020
The following essay is composed of two parts: chapter I tries to trace the main intention for Hans Blumenberg’s “Theorie der Unbegrifflichkeit”, which was developed between 1960 and 1980, and wants to integrate it into the transdisciplinary paradigm of ...
Wolfgang Riedel
doaj   +1 more source

Heterogeneity and proliferation of invasive cancer subclones in game theory models of the Warburg effect [PDF]

, 2015
OBJECTIVES: The Warburg effect, the switch from aerobic energy production to anaerobic glycolysis, promotes tumour proliferation and motility by inducing acidification of the tumour microenvironment.
Archetti, Archetti, Archetti, Archetti, Archetti, Archetti, Bach, Basanta, Basanta, Basanta, Bergers, Bhujwalla, Buchler, Casciari, Feron, Gambhir, Gatenby, Gatenby, Gatenby, Gatenby, Gillies, Griffiths, Hanahan, He, Ibrahim Hashim, Ibrahim Hashim, Kelloff, Kianercy, Kunkel, Lardner, Martin, Martin, Maynard Smith, Mochiki, Park, Patel, Pauwels, Perc, Postovit, Postovit, Rajendran, Robey, Rohzin, Rubin, Schornack, Semenza, Shi, Silva, Smallbone, Smallbone, Sonveaux, Tomlinson, Tomlinson, Warburg, Williams, Wojtkowiak   +55 more
core   +1 more source

Intermediality and Immersion in Gaudenzio Ferrari’s "Adoration of the Magi" in Chapel V of the Sacred Mountain of Varallo

PsicoArt, 2020
This study proposes that intermediality in Renaissance art makes a strong impact on both the aesthetic space and the beholder’s attention, memory, and imagination.
Fabio Tononi
doaj   +1 more source

Dandy-Walker malformation: is the "tail sign" the key sign? [PDF]

, 2015
OBJECTIVE.To demonstrate the value of the "tail sign" in the assessment of Dandy-Walker Malformation (DWM). METHODS: A total of 31fetal MRI, performed before 24 weeks of gestation after second-line US examination between May 2013 and September 2014 ...
Aliberti, C, Bernardo, Silvia, Giancotti, Antonella, Manganaro, Lucia, Porpora, Maria Grazia, Rizzo, G, Saldari, Matteo, Servadei, F, Silvestri, E, Triulzi, F, Vinci, Valeria   +10 more
core   +1 more source

Phospho‐tyrosine dependent protein–protein interaction network

Molecular Systems Biology, 2015
Post‐translational protein modifications, such as tyrosine phosphorylation, regulate protein–protein interactions (PPIs) critical for signal processing and cellular phenotypes.
Arndt Grossmann, Nouhad Benlasfer, Petra Birth, Anna Hegele, Franziska Wachsmuth, Luise Apelt, Ulrich Stelzl   +6 more
doaj   +1 more source