Results 101 to 110 of about 108,453 (351)
Metformin as a Therapeutic Target in Endometrial Cancers. [PDF]
, 2018 Endometrial cancer is the most common gynecologic malignancy in developed countries. Its increasing incidence is thought to be related in part to the rise of metabolic syndrome, which has been shown to be a risk factor for the development of ...
Johnson, Jennifer +6 more
core +2 more sources
THE WARBURG EFFECT AND BEYOND [PDF]
Neuro-Oncology, 2014 BACKGROUND: Pyruvate kinase M2 (PKM2) is highly expressed in multiple cancer types and contributes to the Warburg effect. METHODS: We have used various approaches including animal studies, human GBM specimen analyses, and biochemical studies, to understand the cellular functions of PKM2.
openaire +1 more source
Advanced Healthcare Materials, EarlyView.Neural electrodes face a mechanical mismatch with brain tissue. This study proposes a bioelectromechanical coupling strategy using an ultra‐flexible electrode designed for synchronized motion. Optimized to match brain tissue stiffness, it achieves dual signal acquisition and micromotion sensing, with characterized interfacial forces and piezoresistive ...
Donglei Chen +11 more
wiley +1 more source
Marine Drugs, 2020 The phenomenon of high sugar consumption by tumor cells is known as Warburg effect. It results from a high glycolysis rate, used by tumors as preferred metabolic pathway even in aerobic conditions.
Sergey A. Dyshlovoy +16 more
doaj +1 more source
Blood, 2018 Abstract Mature B cells recognize and respond in a highly-specific fashion to a multitude of environmental antigens through membrane-bound immunoglobulins forming together with the Igα and Igβ proteins a functional unit called the B cell antigen receptor (BCR).
Stefano Casola +11 more
openaire +1 more source
Transient Charging of Mixed Ionic‐Electronic Conductors by Anomalous Diffusion
Advanced Materials, EarlyView.This article explores charge transport in mixed ionic‐electronic conductors (MIECs) through electrochemical impedance spectroscopy and transient current analysis. Focusing on PEDOT:PSS, WO3, and n‐doped PBDF, it uncovers the impact of anomalous diffusion via fractional modeling. The study reveals key correlations that deepen understanding and guide the
Heyi Zhang +9 more
wiley +1 more source
A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension
Nature Communications, 2019 Pulmonary hypertension is characterized by a metabolic switch similar to the Warburg effect in cancer. Here Dabral et al. describe a RASSF1a-HIF-1α feedforward loop driving the Warburg effect both in a mouse model of hypoxia-induced pulmonary ...
Swati Dabral +14 more
doaj +1 more source
Emerging role of the pentose phosphate pathway in hepatocellular carcinoma [PDF]
, 2017 In recent years, there has been a revival of interest in metabolic changes of cancer cells as it has been noticed that malignant transformation and metabolic reprogramming are closely intertwined.
Columbano, Amedeo +2 more
core +2 more sources
Distinct metabolic transcriptional patterns and Warburg effect in porcine model of ischaemic cardiomyopathy [PDF]
, 2021 Daniel Baz-Lopez +4 more
openalex +1 more source
Advanced Materials, EarlyView.A high‐capacity polyimide‐linked porous organic polymer (HAT‐PTO) incorporating numerous redox‐active centers is synthesized via a hydrothermal reaction, delivering a high theoretical capacity of 484 mAh g−1. In situ hybridization with carboxyl‐functionalized multiwalled carbon nanotubes enhances conductivity and stability, achieving 397 mAh g−1 at C ...
Arindam Mal +7 more
wiley +1 more source