Results 251 to 260 of about 108,453 (351)

Hydrated proton complexes supplementation for tumor microenvironment reprogramming: a bioenergetic strategy targeting the Warburg effect and mitochondrial dysfunction. [PDF]

Front Oncol
Edgar AL, Lopes LFD, Lopes EG, Felin ID, Felin CR, Gaspary JFP.   +5 more
europepmc   +1 more source

Dynamic pH profiles drive higher cell‐specific and volumetric productivity

Biotechnology Progress, EarlyView.
Implementation of dyamic pH profiles for increased CHO cell culture productivity. Abstract Mammalian cell cultures in bioreactors rely heavily on critical process parameter control to ensure optimal growth, productivity, and reproducibility to produce recombinant therapeutic proteins. Culture pH has been shown to be a critical parameter that influences
Stephanie R. Klaubert, Dylan G. Chitwood, Danqia Peng, Erin Redman, Ji Young L. Anderson, Nicholas R. Sandoval, Sarah W. Harcum   +6 more
wiley   +1 more source

Phase Ia/b Multicenter Study of BPM31510IV Targeting Mitochondrial Metabolism/Warburg Effect as Monotherapy and Combination Chemotherapy in Solid Tumor Patients. [PDF]

Cancer Res Commun
Subbiah V, Yu PP, Sarangarajan R, Kiebish MA, Rodrigues LO, Miller GM, Akmaev VR, Luan S, McCook JP, Tanna N, Reilly T, Chen E, Bussberg V, Ravipaty S, Vishnudas VK, Gesta S, Lucius D, Bruce C, Hazarika S, Lyng A, Klotz A, Tolstikov V, Stevens J, Chua VS, Granger E, Tekumalla PK, Benaim E, Modur V, Rudoltz MS, Song PY, Tagawa ST, Hendifer A, Chawla SP, Shah MA, Hong DS, Zinner R, Narain NR, Kundranda MN.   +37 more
europepmc   +1 more source

Fundamental role of Warburg effect in various pathophysiological processes

, 2017
Vasanthakumar Natesan
openalex   +1 more source

Analysis of the economic viability and environmental impacts of a conceptual process model for the recovery of lactic acid from spent media in cultivated meat production

Biotechnology Progress, EarlyView.
Abstract Scaled production of cultivated meat (CM) will co‐produce large volumes of spent media. Recycling of abundant metabolites such as lactic acid in spent media offers an opportunity for valorization and reduction of the carbon footprint of CM production; however, the feasibility has yet to be examined.
Josh Wimble, Reina Ashizawa, Elliot W. Swartz   +2 more
wiley   +1 more source

Refractory Hypoglycemia Secondary to the Warburg Effect in Diffuse Large B-Cell Lymphoma. [PDF]

JCEM Case Rep
Shiomura M, Watanabe T, Yasuda S, Fukuda I, Yamada T, Shichiri M.   +5 more
europepmc   +1 more source

Disrupting the ‘Warburg effect’ re-routes cancer cells to OXPHOS offering a vulnerability point via ‘ferroptosis’-induced cell death

, 2017
Maša Ždralević, Milica Vučetić, Boutaina Daher, Ibtissam Marchiq, Scott K. Parks, Jacques Pouysségur   +5 more
openalex   +1 more source

Dynamics of natural killer cell function upon recurrent stimulation

Biotechnology Progress, EarlyView.
Weekly stimulation of peripheral blood‐derived NK cells with engineered K562 feeder cells resulted in two distinct growth phases, shifting around Day 21–26. Cells in growth phase 2 exhibited slower growth, reduced metabolic activity, and lower cytotoxicity than cells from growth phase 1, which has implications for NK cell biomanufacturing.
Jennifer One, Janani Narayan, Frank Cichocki, Wei‐Shou Hu, Samira M. Azarin   +4 more
wiley   +1 more source

Diallyl Trisulfide Enhances Doxorubicin Chemosensitivity by Inhibiting the Warburg Effect and Inducing Apoptosis in Breast Cancer Cells. [PDF]

J Cancer
Chang CM, Wang WJ, Mhone TG, Ho WK, Chen CJ, Ng SS, Li CC, Kuo CH, Huang CY, Kuo WW.   +9 more
europepmc   +1 more source

Interfacial Modulation of Lithium Deposition via an Adaptive Poly(Ether‐Thiourea) Protective Layer

Carbon Energy, EarlyView.
An efficient adaptive protective layer based on thiourea H‐bonded supramolecular polymer is developed for lithium metal anodes. Physically, its viscoelastic properties promote a homogeneous Li+ flux, effectively preventing dendrite formation. Chemically, the polymer facilitates the formation of beneficial SEI components, such as Li₃N and Li₂O, greatly ...
Yongsheng Zhang, Xiaolong He, Yinyu Xiang, Lieke M. H. Germain, Marco Di Michiel, Pierre‐Olivier Autran, Yutao Pei, Petra Rudolf, Giuseppe Portale   +8 more
wiley   +1 more source