Results 251 to 260 of about 13,460,861 (391)

Tumor Microenvironment‐Responsive Nanomedicines for Potentiating Cancer Immunotherapy

Advanced Science, EarlyView.
Strategies for TME‐responsive Nanomaterials to Potentiate Cancer Immunotherapy. Abstract Immunotherapy has emerged as a transformative paradigm in oncology, yet its clinical efficacy remains constrained by the immunosuppressive tumor microenvironment and inadequate spatiotemporal control of existing modalities, resulting in suboptimal patient response ...
Qianqian Huang, Fan Tong, Jiantao Chen, Muzaffar Kayumov, Yue Lv, Yajun Shi, Bengui Ye, Huile Gao   +7 more
wiley   +1 more source

Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages [PDF]

, 2015
Eva M. Pålsson‐McDermott, Annie M. Curtis, Gautam Goel, Mario Lauterbach, Frederick J. Sheedy, Laura E. Gleeson, Mirjam W.M. van den Bosch, Susan R. Quinn, Raquel Domingo-Fernandéz, Daniel Johnston, Jian‐kang Jiang, William J. Israelsen, Joseph Keane, Craig J. Thomas, Clary B. Clish, Matthew G. Vander Heiden, Ramnik J. Xavier, Luke O'neill   +17 more
openalex   +1 more source

Capsaicin ameliorates inflammation in a TRPV1-independent mechanism by inhibiting PKM2-LDHA-mediated Warburg effect in sepsis.

Cell Chemical Biology, 2022
Qian Zhang, Piao Luo, Fei Xia, Huan Tang, Jiayun Chen, Junzhe Zhang, Dandan Liu, Yongping Zhu, Yanqing Liu, Liwei Gu, Liuhai Zheng, Zhijie Li, Fan Yang, Li Dai, F. Liao, Chengchao Xu, Jigang Wang   +16 more
semanticscholar   +1 more source

Spatial Transcriptomics and snRNA‐seq Expose CAF Niches Orchestrating Dual Stromal‐Immune Barriers in Hepatocellular Carcinoma

Advanced Science, EarlyView.
HmmyCAFs may form a triple immunosuppressive niche: possibly secrete ECM (POSTN, etc.) as physical barriers to block CD8⁺ T cells, induce CD8⁺ T exhaustion via those molecules, and use HIF‐1α‐driven metabolism to create acidic, nutrient‐poor microenvironments that suppress T cells.
Yingxue Li, Changxiang Huan, Haoting Sun, Wei Zhang, Zhen Guo, Chuanyu Li, Jia Yao, Zhiqi Zhang, Shizhe Yu, Qiongzhu Dong, Lunxiu Qin, Jinze Li, Lianqun Zhou   +12 more
wiley   +1 more source

Hydrated proton complexes supplementation for tumor microenvironment reprogramming: a bioenergetic strategy targeting the Warburg effect and mitochondrial dysfunction. [PDF]

Front Oncol
Edgar AL, Lopes LFD, Lopes EG, Felin ID, Felin CR, Gaspary JFP.   +5 more
europepmc   +1 more source

Synergistic Effect of Dual‐Functional Groups in MOF‐Modified Separators for Efficient Lithium‐Ion Transport and Polysulfide Management of Lithium‐Sulfur Batteries

Advanced Science, EarlyView.
This study developed a bifunctional metal‐organic framework (UIO‐66‐NH2‐HSO3) modified separator, which shows dual functionality in anchoring LiPS and facilitating Li+ transport. Due to the systematic modification, the assembled LSBs deliver excellent high‐rate performance and ultra‐long cycling stability.
Zheng Liu, Wanchang Feng, Haoyang Xu, Zilin Yang, Wenting Li, Mohsen Shakouri, Hsiao‐Chien Chen, Fan Zhang, Huan Pang   +8 more
wiley   +1 more source

Diallyl Trisulfide Enhances Doxorubicin Chemosensitivity by Inhibiting the Warburg Effect and Inducing Apoptosis in Breast Cancer Cells. [PDF]

J Cancer
Chang CM, Wang WJ, Mhone TG, Ho WK, Chen CJ, Ng SS, Li CC, Kuo CH, Huang CY, Kuo WW.   +9 more
europepmc   +1 more source

Dual Regulation on Structure‐Interface Enables Coal‐Tar‐Pitch‐Based Hard Carbon Anodes with High Rate and Storage Performance for Sodium Ion Batteries

Advanced Science, EarlyView.
This study utilizes coal tar pitch (waste product generated during the coal conversion process) as a raw material. The core concept of synergistic “structure‐interface” regulation, an innovative system from molecular design to microcrystalline optimization, pore reconstruction, and interface regulation is proposed.
Xinmeng Xu, Kun Wang, Beibei Han, Jianke Li, Baigang An, Chengguo Sun, Guiying Xu, Zewei Li, Wenwu Zhang, Zhenbo Wang, Weimin Zhou   +10 more
wiley   +1 more source

Refractory Hypoglycemia Secondary to the Warburg Effect in Diffuse Large B-Cell Lymphoma. [PDF]

JCEM Case Rep
Shiomura M, Watanabe T, Yasuda S, Fukuda I, Yamada T, Shichiri M.   +5 more
europepmc   +1 more source

Fructose: the sweet(er) side of the Warburg effect. [PDF]

Cell Death Differ
Frezza C.
europepmc   +1 more source