The metabolomic profile of gamma-irradiated human hepatoma and muscle cells reveals metabolic changes consistent with the Warburg effect [PDF]
, 2016 The two human cell lines HepG2 from hepatoma and HMCL-7304 from striated muscle were γ-irradiated with doses between 0 and 4 Gy. Abundant γH2AX foci were observed at 4 Gy after 4 h of culture post-irradiation.
Beyoğlu, Diren +4 more
core +5 more sources
Relevance of the Warburg Effect in Tuberculosis for Host-Directed Therapy
Frontiers in Cellular and Infection Microbiology, 2020 Tuberculosis (TB) was responsible for more deaths in 2019 than any other infectious agent. This epidemic is exacerbated by the ongoing development of multi-drug resistance and HIV co-infection.
Bridgette M. Cumming +4 more
doaj +1 more source
The reverse warburg effect in osteosarcoma
Oncotarget, 2014 Osteosarcoma is a rare primary malignant tumor of the bone. It is a childhood cancer and has a peak incidence in the second decade of life. Unfortunately, osteosarcoma has a poor prognosis because of its metastatic dissemination to the bone and to the lung.
Michael P. Lisanti +2 more
openaire +3 more sources
Tyrosine Kinase Signaling in Cancer Metabolism: PKM2 Paradox in the Warburg Effect
Frontiers in Cell and Developmental Biology, 2018 The Warburg Effect, or aerobic glycolysis, is one of the major metabolic alterations observed in cancer. Hypothesized to increase a cell's proliferative capacity via regenerating NAD+, increasing the pool of glycolytic biosynthetic intermediates, and ...
Elizabeth K. Wiese +3 more
doaj +1 more source
Molecular Medicine, 2023 Background The main cause of high mortality from sepsis is that immunosuppression leads to life-threatening organ dysfunction, and reversing immunosuppression is key to sepsis treatment. Interferon γ (IFNγ) is a potential therapy for immunosuppression of
Xu-zhe Fu, Yu Wang
doaj +1 more source
SparseFormer: Attention-based Depth Completion Network [PDF]
arXiv, 2022 Most pipelines for Augmented and Virtual Reality estimate the ego-motion of the camera by creating a map of sparse 3D landmarks. In this paper, we tackle the problem of depth completion, that is, densifying this sparse 3D map using RGB images as guidance.
arxiv
Nerfbusters: Removing Ghostly Artifacts from Casually Captured NeRFs [PDF]
arXiv, 2023 Casually captured Neural Radiance Fields (NeRFs) suffer from artifacts such as floaters or flawed geometry when rendered outside the camera trajectory. Existing evaluation protocols often do not capture these effects, since they usually only assess image quality at every 8th frame of the training capture.
arxiv
Alzheimer's disease: the amyloid hypothesis and the Inverse Warburg effect. [PDF]
, 2015 Epidemiological and biochemical studies show that the sporadic forms of Alzheimer's disease (AD) are characterized by the following hallmarks: (a) An exponential increase with age; (b) Selective neuronal vulnerability; (c) Inverse cancer comorbidity. The
Demetrius, L.A. +2 more
core +4 more sources
Unmasking the Warburg Effect: Unleashing the Power of Enzyme Inhibitors for Cancer Therapy
Drugs and Drug Candidates, 2023 The Warburg effect (or aerobic glycolysis), which was first described in 1926 by Otto Heinrich Warburg, consists of the change in glucose metabolism in cancer cells.
Eduardo Angulo-Elizari +5 more
doaj +1 more source
The Warburg and Crabtree effects: On the origin of cancer cell energy metabolism and of yeast glucose repression [PDF]
, 2011 During the last decades a considerable amount of research has been focused on cancer. Recently, tumor cell metabolism has been considered as a possible target for cancer therapy.
Devin, Anne +2 more
core +2 more sources