Results 61 to 70 of about 9,923,041 (290)

Hypoxia-induced Circular RNA hsa_circ_0006508 Promotes the Warburg Effect in Colorectal Cancer Cells

Balkan Medical Journal, 2023
Background: The hypoxia-induced Warburg effect promotes colorectal cancer malignancy with altered circular RNA (circRNA) expression. Aims: To investigate the association with the Warburg effect in colorectal cancer and whether has_circ_0006508 can be ...
Yugang Xu, Ying Zhang, Wenli Hao, Wen Zhao, Guang Yang, Changqing Jing   +5 more
doaj   +1 more source

The immunological Warburg effect: Can a metabolic‐tumor‐stroma score (MeTS) guide cancer immunotherapy? [PDF]

, 2020
The "glycolytic switch" also known as the "Warburg effect" is a key feature of tumor cells and leads to the accumulation of lactate and protons in the tumor environment.
Kreutz, Marina, Katja Evert, Kathrin Renner, Renner, Kathrin, Evert, Katja, Siska, Peter J., Peter J. Siska, Katrin Singer, Marina Kreutz, Singer, Katrin   +9 more
core   +1 more source

Engineering a Fluorinated AlPO4 Interface: Toward High Initial Coulombic Efficiency and Stable Oxygen Redox in Li‐Rich Layered Oxide Cathodes

Advanced Functional Materials, EarlyView.
We report a chemically incorporated fluorinated AlPO4 (AlPO4‐F) architecture that functions as a multifunctional “interfacial fortress” for Li‐rich layered oxides (LLOs). By modulating the surface potential to –32.16 mV, this architecture enriches Li+ concentration and repels detrimental electrolyte anions.
Hojun Moon, Harim Jeong, Younghwon Kim, Buseong Kim, Geunhyeong Kim, Suyeon Lee, Jeongjin Lee, Joonwoo Kim, Jemin Lee, Youngsoo Kim, Young‐Il Kim, Dae Won Cho, Jeeyoung Yoo, Misook Kang   +13 more
wiley   +1 more source

Curcumin decreases Warburg effect in cancer cells by down-regulating pyruvate kinase M2 via mTOR-HIF1α inhibition

Scientific Reports, 2018
Warburg effect is an emerging hallmark of cancer cells with pyruvate kinase M2 (PKM2) as its key regulator. Curcumin is an extensively-studied anti-cancer compound, however, its role in affecting cancer metabolism remains poorly understood.
Farid Ahmad Siddiqui, Gopinath Prakasam, Shilpi Chattopadhyay, Asad Ur Rehman, Rayees Ahmad Padder, Mohammad Afaque Ansari, Rasha Irshad, Kailash Mangalhara, Rameshwar N. K. Bamezai, Mohammad Husain, Syed Mansoor Ali, Mohammad Askandar Iqbal   +11 more
doaj   +1 more source

Myc and the Warburg Effect

Blood, 2018
Abstract Mature B cells recognize and respond in a highly-specific fashion to a multitude of environmental antigens through membrane-bound immunoglobulins forming together with the Igα and Igβ proteins a functional unit called the B cell antigen receptor (BCR).
Stefano Casola, Gabriele Varano, Laura Perucho, Marianna Ossorio, Federica Zanardi, Martina Sormani, Valentina Petrocelli, Christin Zasada, Stefan Kempa, Klaus Rajewsky, Maurilio Ponzoni, Fabio Facchetti   +11 more
openaire   +1 more source

Self‐Adaptive Gradient Interphase Enables Durable Solid‐State Lithium Metal Batteries

Advanced Functional Materials, EarlyView.
This work presents a machine learning‐guided interfacial design that forms a self‐adaptive graded interphase on lithium metal anode. A B105M40 composite interlayer evolves into lithiophilic, porous, and fast‐ion‐conducting phases, enabling intimate contact, dendrite suppression, and uniform lithium deposition.
Hongmin Liu, Rui Li, Yitao Lou, Xinran Gao, Min Xu, Shijian Wang, Nana Wang, Huakun Liu, Guoxiu Wang, Zhongchao Bai   +9 more
wiley   +1 more source

Hippocampal warburg effect mediates hydrogen sulfide-ameliorated diabetes-associated cognitive dysfunction: Involving promotion of hippocampal synaptic plasticity

Neuroscience Research
Our previous studies have reported that hydrogen sulfide (H2S) has ability to improve diabetes-associated cognitive dysfunction (DACD), but the exact mechanisms remain unknown.
Run-Qi Li, Wei-Wen Zhu, Cheng Li, Ke-Bin Zhan, Ping Zhang, Fan Xiao, Jia-Mei Jiang, Wei Zou   +7 more
doaj   +1 more source

Ultrafast Vertical Organic Electrochemical Transistors With Ion‐Permeable Conductive Polymer Top Electrodes

Advanced Materials, EarlyView.
Vertical organic electrochemical transistors (vOECTs) are limited in speed by ion‐impermeable metal electrodes that slow ion injection. Using ion‐permeable PBFDO top electrodes allows direct vertical ion injection into BBL channels, achieving high current densities (>400 A cm−2), large on/off ratios (>106), and ultrafast switching in 28 µs. This sets a
Han‐Yan Wu, Yingxue An, Luigi Fabiano, Qifan Li, Qingqing Wang, Feng Zhang, Wenlong Jin, Miao Xiong, Junpeng Ji, Ugo Bruno, Grzegorz Greczynski, Grazia Maria Lucia Messina, Xianjie Liu, Chi‐Yuan Yang, Simone Fabiano   +14 more
wiley   +1 more source

Transcription factor ONECUT3 regulates HDAC6/HIF-1α activity to promote the Warburg effect and tumor growth in colorectal cancer

Cell Death and Disease
The Warburg effect, also known as aerobic glycolysis, plays a crucial role in the onset and progression of colorectal cancer (CRC), although its mechanism remains unclear.
Ruixue Huo, Weihan Li, Hao Wu, Kexin He, Hao Wang, Shan Zhang, Shu-Heng Jiang, Rongkun Li, Junli Xue   +8 more
doaj   +1 more source

The Warburg effect: a balance of flux analysis [PDF]

Metabolomics, 2014
Cancer metabolism is characterized by increased macromolecular syntheses through coordinated increases in energy and substrate metabolism. The observation that cancer cells produce lactate in an environment of oxygen sufficiency (aerobic glycolysis) is a central theme of cancer metabolism known as the Warburg effect.
Vaitheesvaran, B, Xu, J, Yee, J, Lu, QY, Go, VL, Xiao, GG, Lee, WN   +6 more
openaire   +5 more sources