Results 71 to 80 of about 47,258 (264)

HBO regulates the Warburg effect of hypoxic HCC cells through miR-103a-3p/TRIM35

Discover Oncology
Background There are a lot of studies on the treatment of tumors with hyperbaric oxygen, while most of them are in breast cancer, prostate cancer and so on.
Yuting Ding, Wenkang Luan, Zhe Wang, Bo Xie, Chengfa Sun   +4 more
doaj   +1 more source

Polyimide‐Linked Hexaazatriphenylene‐Based Porous Organic Polymer with Multiple Redox‐Active Sites as a High‐Capacity Organic Cathode for Lithium‐Ion Batteries

Advanced Materials, EarlyView.
A high‐capacity polyimide‐linked porous organic polymer (HAT‐PTO) incorporating numerous redox‐active centers is synthesized via a hydrothermal reaction, delivering a high theoretical capacity of 484 mAh g−1. In situ hybridization with carboxyl‐functionalized multiwalled carbon nanotubes enhances conductivity and stability, achieving 397 mAh g−1 at C ...
Arindam Mal, Jonathan Caroni, Asia Patriarchi, Olivera Luzanin, Rafael Ramos, Jan Bitenc, Manuel Melle‐Franco, Manuel Souto   +7 more
wiley   +1 more source

THE WARBURG EFFECT AND BEYOND [PDF]

Neuro-Oncology, 2014
BACKGROUND: Pyruvate kinase M2 (PKM2) is highly expressed in multiple cancer types and contributes to the Warburg effect. METHODS: We have used various approaches including animal studies, human GBM specimen analyses, and biochemical studies, to understand the cellular functions of PKM2.
openaire   +1 more source

Electrically Readable Lateral Flow Assay Using Organic Transistors for Diagnostic Applications

Advanced Materials, EarlyView.
Electrolyte‐gated organic field‐effect transistors (EGOFETs) are integrated with lateral flow (LF) paper fluidics to create a reusable, portable, and low‐cost point‐of‐care (PoC) diagnostic test. The devices are validated for Human Immunoglobulin G detection, achieving high sensitivity (0.1 fm), selectivity, and reproducibility with rapid results in 20–
María Jesús Ortiz‐Aguayo, Carme Martínez‐Domingo, Diego Gutiérrez, Dean Kos, Marta Mas‐Torrent   +4 more
wiley   +1 more source

Myc and the Warburg Effect

Blood, 2018
Abstract Mature B cells recognize and respond in a highly-specific fashion to a multitude of environmental antigens through membrane-bound immunoglobulins forming together with the Igα and Igβ proteins a functional unit called the B cell antigen receptor (BCR).
Stefano Casola, Gabriele Varano, Laura Perucho, Marianna Ossorio, Federica Zanardi, Martina Sormani, Valentina Petrocelli, Christin Zasada, Stefan Kempa, Klaus Rajewsky, Maurilio Ponzoni, Fabio Facchetti   +11 more
openaire   +1 more source

Wafer‐Scale Synthesis of Molecularly Engineered 2D Covalent Organic Framework Films for Highly‐Sensitive and Rapid‐Response Humidity Sensing

Advanced Materials, EarlyView.
We report molecularly engineered 2D COF films for high‐performance humidity sensors. The developed COFTPT‐THTA ultrathin film features triazine‐functionalized π‐conjugated backbones and high‐density surface hydroxyl groups. This unique architecture facilitates an electron‐proton coupled transport mechanism.
Liangyu Dong, Can Wang, Jiawen Liu, Bin Han, Bo Zhou, Valentina Girelli Consolaro, Nikita Denisov, Arno Annys, Johan Verbeeck, Verónica Montes‐García, Xinyi Shao, Wei Song, Bin Xu, Sara Bals, Zhaoyang Liu, Wenjing Tian, Paolo Samorì   +16 more
wiley   +1 more source

Inspired by Sea Urchins: Warburg Effect Mediated Selectivity of Novel Synthetic Non-Glycoside 1,4-Naphthoquinone-6S-Glucose Conjugates in Prostate Cancer

Marine Drugs, 2020
The phenomenon of high sugar consumption by tumor cells is known as Warburg effect. It results from a high glycolysis rate, used by tumors as preferred metabolic pathway even in aerobic conditions.
Sergey A. Dyshlovoy, Dmitry N. Pelageev, Jessica Hauschild, Yurii E. Sabutskii, Ekaterina A. Khmelevskaya, Christoph Krisp, Moritz Kaune, Simone Venz, Ksenia L. Borisova, Tobias Busenbender, Vladimir A. Denisenko, Hartmut Schlüter, Carsten Bokemeyer, Markus Graefen, Sergey G. Polonik, Victor Ph. Anufriev, Gunhild von Amsberg   +16 more
doaj   +1 more source

Ultrafast Vertical Organic Electrochemical Transistors With Ion‐Permeable Conductive Polymer Top Electrodes

Advanced Materials, EarlyView.
Vertical organic electrochemical transistors (vOECTs) are limited in speed by ion‐impermeable metal electrodes that slow ion injection. Using ion‐permeable PBFDO top electrodes allows direct vertical ion injection into BBL channels, achieving high current densities (>400 A cm−2), large on/off ratios (>106), and ultrafast switching in 28 µs. This sets a
Han‐Yan Wu, Yingxue An, Luigi Fabiano, Qifan Li, Qingqing Wang, Feng Zhang, Wenlong Jin, Miao Xiong, Junpeng Ji, Ugo Bruno, Grzegorz Greczynski, Grazia Maria Lucia Messina, Xianjie Liu, Chi‐Yuan Yang, Simone Fabiano   +14 more
wiley   +1 more source

A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension

Nature Communications, 2019
Pulmonary hypertension is characterized by a metabolic switch similar to the Warburg effect in cancer. Here Dabral et al. describe a RASSF1a-HIF-1α feedforward loop driving the Warburg effect both in a mouse model of hypoxia-induced pulmonary ...
Swati Dabral, Christian Muecke, Chanil Valasarajan, Mario Schmoranzer, Astrid Wietelmann, Gregg L. Semenza, Michael Meister, Thomas Muley, Tamina Seeger-Nukpezah, Christos Samakovlis, Norbert Weissmann, Friedrich Grimminger, Werner Seeger, Rajkumar Savai, Soni S. Pullamsetti   +14 more
doaj   +1 more source

Warburg Effect in Oncology

International Journal of Trends in OncoScience
The Warburg effect, defined by cancer cells’ preference for aerobic glycolysis over mitochondrial oxidative phosphorylation for energy production, has been a central topic in cancer research since its identification in 1924. This process involves elevated glucose uptake and lactate production, even in the presence of oxygen, supporting rapid cell ...
Dr. T. Shehnaz Begum, Prof Dr. Ammar A. Razzak Mahmood, Maya Prabhakaran Pillai V, Dr. John Abraham, Dr. Vanitha Innocent Rani, Amutha Chellathurai, Dr. Somenath Ghosh   +6 more
openaire   +1 more source