Quantitative constraint-based computational model of tumor-to-stroma coupling via lactate shuttle [PDF]
Cancer cells utilize large amounts of ATP to sustain growth, relying primarily on non-oxidative, fermentative pathways for its production.
CAPUANI, FABRIZIO +3 more
core +1 more source
THE WARBURG EFFECT AND BEYOND [PDF]
BACKGROUND: Pyruvate kinase M2 (PKM2) is highly expressed in multiple cancer types and contributes to the Warburg effect. METHODS: We have used various approaches including animal studies, human GBM specimen analyses, and biochemical studies, to understand the cellular functions of PKM2.
openaire +1 more source
Chemically Processed Porous V2O5 Thin‐Film Cathodes for High‐Performance Thin‐film Zn‐Ion Batteries
This study presents a rapid, cost‐effective chemical method for fabricating porous vanadium oxide thin‐film cathodes, aimed at enhancing charge storage in Zinc‐ion thin‐film batteries. The approach promises high‐performance, safe, and affordable thin‐film batteries, with industrial viability through efficient processing of highly porous cathodes ...
Jingli Luo +9 more
wiley +1 more source
Transcriptomic-metabolomic reprogramming in EGFR-mutant NSCLC early adaptive drug escape linking TGFβ2-bioenergetics-mitochondrial priming. [PDF]
The impact of EGFR-mutant NSCLC precision therapy is limited by acquired resistance despite initial excellent response. Classic studies of EGFR-mutant clinical resistance to precision therapy were based on tumor rebiopsies late during clinical tumor ...
Bagai, Rakesh +14 more
core +1 more source
Laser‐Induced Graphene from Waste Almond Shells
Almond shells, an abundant agricultural by‐product, are repurposed to create a fully bioderived almond shell/chitosan composite (ASC) degradable in soil. ASC is converted into laser‐induced graphene (LIG) by laser scribing and proposed as a substrate for transient electronics.
Yulia Steksova +9 more
wiley +1 more source
Reversing the Warburg effect to control cancer: a review of diet-based solutions
Warburg effect is a form of cellular metabolism commonly used by cancer cells, in which, consumption of glucose and production of acidic cell metabolic wastes take place at a considerably higher rate.
Hassan Bahrami +2 more
doaj
Hypoxia-induced Circular RNA hsa_circ_0006508 Promotes the Warburg Effect in Colorectal Cancer Cells
Background: The hypoxia-induced Warburg effect promotes colorectal cancer malignancy with altered circular RNA (circRNA) expression. Aims: To investigate the association with the Warburg effect in colorectal cancer and whether has_circ_0006508 can be ...
Yugang Xu +5 more
doaj +1 more source
Abstract Mature B cells recognize and respond in a highly-specific fashion to a multitude of environmental antigens through membrane-bound immunoglobulins forming together with the Igα and Igβ proteins a functional unit called the B cell antigen receptor (BCR).
Stefano Casola +11 more
openaire +1 more source
Nuclear PKM2 regulates the Warburg effect [PDF]
Pyruvate kinase is a rate-limiting glycolytic enzyme. The PKM1 and PKM2 isoforms result from mutually exclusive alternative splicing of the PKM pre-mRNA. PKM2 rather than PKM1 regulates the Warburg effect and tumorigenesis by poorly understood mechanisms.
Weiwei, Yang, Zhimin, Lu
openaire +2 more sources
Optimizing (1‐x) BiFeO3‐xCaTiO3 Perovskites: A Pathway to Efficient Flexible Energy Storage
Perovskite materials, like BFO CTO, are popular due to their high conductivity, low cost, and wide availability. In this work a symmetric electrochemical cell based on BFO‐CTO shows a charge of 3.356 C.cm⁻2, giving a specific capacitance of 2.79 mF.cm⁻2 at 1 mV.s⁻2.
Febin Paul +7 more
wiley +1 more source

