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Mechanism of exacerbation of traumatic brain injury under warfarin anticoagulation in male mice. [PDF]

open access: yesPLoS ONE
IntroductionTraumatic brain injury (TBI) is exacerbated in patients on antithrombotic medications, with warfarin leading to increased bleeding in some cases.
Yuki Tatara   +3 more
doaj   +2 more sources

Optimizing Warfarin Dosing using Deep Reinforcement Learning [PDF]

open access: yesJournal of Biomedical Informatics, 137 (2023) 104267, 2022
Warfarin is a widely used anticoagulant, and has a narrow therapeutic range. Dosing of warfarin should be individualized, since slight overdosing or underdosing can have catastrophic or even fatal consequences. Despite much research on warfarin dosing, current dosing protocols do not live up to expectations, especially for patients sensitive to ...
arxiv   +1 more source

Direct Oral Anticoagulants Versus Warfarin in Patients With Atrial Fibrillation: Patient-Level Network Meta-Analyses of Randomized Clinical Trials With Interaction Testing by Age and Sex

open access: yesCirculation, 2022
Supplemental Digital Content is available in the text. Background: Direct oral anticoagulants (DOACs) are preferred over warfarin for stroke prevention in atrial fibrillation.
A. Carnicelli   +31 more
semanticscholar   +1 more source

A Case Of Late-onset Warfarin Induced Skin Necrosis Resulting In Mortality

open access: yesHitit Medical Journal, 2023
Warfarin-induced skin necrosis is a rare complication of warfarin therapy and is associated with high mortality. Here, we present a case of warfarin-induced skin necrosis, that was fatal in a 53-year-old female patient who was started on warfarin ...
Pınar Korkmaz, Sinem Bayrakçı
doaj   +1 more source

Fasting and warfarin [PDF]

open access: yesJournal of Fasting and Health, 2014
Recently, we reported the findings of a study on the effects of Ramadan fasting on a group of 32 Muslim patients taking warfarin.13 Weekly INR (international normalized ratio) readings were taken from subjects with previously stable INRs over a three-month period spanning pre-Ramadan to post-Ramadan. We found a statistically significant increase in the
HJ Ng, YF Lai
openaire   +3 more sources

Rivaroxaban versus warfarin in nonvalvular atrial fibrillation.

open access: yesNew England Journal of Medicine, 2011
BACKGROUND The use of warfarin reduces the rate of ischemic stroke in patients with atrial fibrillation but requires frequent monitoring and dose adjustment.
S. Pearson, R. Troughton, A. Richards
semanticscholar   +2 more sources

Apixaban compared with warfarin to prevent thrombosis in thrombotic antiphospholipid syndrome: a randomized trial

open access: yesBlood Advances, 2021
Key Points The primary outcome, stroke, occurred in 6 of 23 patients randomized to apixaban compared with 0 of 25 patients randomized to warfarin. This study with limitations suggests that apixaban is not an equitable substitute for warfarin to prevent ...
S. Woller   +11 more
semanticscholar   +1 more source

Bleeding Incidence in Patients Administered with Warfarin at Secondary Hospitals in Yogyakarta Province

open access: yesIndonesian Journal of Pharmacy, 2020
Warfarin is an oral anticoagulant most-commonly prescribed for prevention and treatment of thromboembolism. It is widely acknowledged that warfarin has both narrow therapeutic index and various drug-food interactions, thus carrying the risk of ...
Vitarani D.A Ningrum   +4 more
doaj   +1 more source

Patterns of warfarin use in subgroups of patients with atrial fibrillation: a cross-sectional analysis of 430 general practices in the United Kingdom. [PDF]

open access: yesPLoS ONE, 2013
Despite the proven efficacy of warfarin, its use in patients with Atrial Fibrillation (AF) is reportedly low. We investigated the underuse and overuse of warfarin in the management of AF in general practices in the United Kingdom (UK) against the ...
Mohammed A Mohammed   +4 more
doaj   +1 more source

Dabigatran versus warfarin in patients with atrial fibrillation.

open access: yesNew England Journal of Medicine, 2009
BACKGROUND Warfarin reduces the risk of stroke in patients with atrial fibrillation but increases the risk of hemorrhage and is difficult to use. Dabigatran is a new oral direct thrombin inhibitor.
S. Connolly   +19 more
semanticscholar   +1 more source

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