Results 141 to 150 of about 210,353 (388)

Rivaroxaban versus warfarin in nonvalvular atrial fibrillation.

New England Journal of Medicine, 2011
S. Pearson, R. Troughton, A. Richards
semanticscholar   +2 more sources

ANALYSIS OF STRUCTURAL FEATURES OF THE KETO-KETAL ISOMERS OF WARFARIN BY SPECTRAL METHODS

Разработка и регистрация лекарственных средств, 2019
As a result of the studies was shown that the relative ratios of isomers by integration in DMSO-d6: (S, R)-warfarin – (S, S)-warfarin – open chain warfarin are 70%: 28%: 2%; in СDCl3 are 45%: 40%: 15%.
A. Z. Abyshev, K. B. Nguyen, L. N. Zinchuk   +2 more
doaj  

STUDIES ON THE COUMARIN ANTICOAGULANT DRUGS: THE PHARMACODYNAMICS OF WARFARIN IN MAN* [PDF]

, 1963
Robert A. O’Reilly, Paul M. Aggeler, Lois S. Leong   +2 more
openalex   +1 more source

Effectiveness and safety of apixaban versus warfarin in non-valvular atrial fibrillation patients in “real-world” clinical practice

Thrombosis and Haemostasis, 2017
Summary The ARISTOTLE trial showed a risk reduction of stroke/systemic embolism (SE) and major bleeding in non-valvular atrial fibrillation (NVAF) patients treated with apixaban compared to warfarin.
Xiaoyan Li, S. Deitelzweig, A. Keshishian, M. Hamilton, R. Horblyuk, K. Gupta, Xuemei Luo, J. Mardekian, K. Friend, A. Nadkarni, Xianying Pan, G. Lip   +11 more
semanticscholar   +1 more source

Warfarin-related nephropathy [PDF]

Kidney International, 2012
To the Editor: In the July (2) 2011 issue, Brodsky et al.1 purport to demonstrate the consequences of warfarin-related nephropathy (WRN) among a retrospective cohort from the Ohio State University Medical Center. The cohort selection procedure was designed to yield cases of ‘presumptive’ WRN, but may have resulted in selection bias: patients who had a ...
openaire   +3 more sources

Assessing Cytochrome P450 Drug Interaction Risk for Dordaviprone Using Physiologically Based Pharmacokinetic Modeling

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT A physiologically based pharmacokinetic (PBPK) model was developed and verified for dordaviprone, a small molecule with antitumor effects in glioma patients. The model was applied to assess the drug–drug interaction (DDI) potential of dordaviprone as a victim of CYP3A4 inhibitors and inducers, and as a perpetrator of CYP3A4, CYP2C8, CYP2D6 ...
Swati Jaiswal, Nikunjkumar K. Patel, Hannah M. Jones, Savannah McFeely, Shamia L. Faison, Tim Tippin, Odin Naderer   +6 more
wiley   +1 more source

Upper extremity deep vein thrombosis associated with systemic lupus erythematosus and antiphospholipid syndrome

Journal of General and Family Medicine, EarlyView.
Masahiro Yabe, Nozomi Ozaki, Nobuhiro Sato, Norihito Nakamura, Azusa Aoyama, Shuichi Murakami, Yasuo Hirose   +6 more
wiley   +1 more source

A Combined Modeling Approach to Predict the Effect of Gastric Emptying Delay on the Pharmacokinetics of Small Molecules

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Dulaglutide, a long‐acting glucagon‐like peptide‐1 (GLP‐1) receptor agonist, is approved for improving glycemic control and reducing cardiovascular risks in patients with type 2 diabetes mellitus (T2DM). This research investigates the effect of dulaglutide on gastric emptying and its impact on the pharmacokinetics (PK) of orally administered ...
Maria M. Posada, Karen B. Schneck, Bridget L. Morse, Luc R. A. Rougee, Lai San Tham, Jessica F. Rehmel, Brian Thompson, Stephen D. Stamatis, Stephen D. Hall, Gemma L. Dickinson   +9 more
wiley   +1 more source

Piperine Alters the Pharmacokinetics and Anticoagulation of Warfarin in Rats

Journal of Experimental Pharmacology, 2020
Aref Zayed,1 Wahby M Babaresh,1 Ruba S Darweesh,2 Tamam El-Elimat,1 Sahar S Hawamdeh1 1Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid 22110, Jordan; 2Department of ...
Zayed A, Babaresh WM, Darweesh RS, El-Elimat T, Hawamdeh SS   +4 more
doaj  

Interaction of the anticoagulant drug warfarin and its metabolites with human plasma albumin [PDF]

, 1969
Robert A. O’Reilly
openalex   +1 more source