Results 141 to 150 of about 192,309 (409)

Simultaneous Effect of Vitamin C and Warfarin on Coagulation Pathways of Rats

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2009
Introduction: The aim of the present study was to assess variations in coagulating pathways after simultaneous administration of warfarin and vitamin C. Methods: A total of 50 Wistar rats were selected.
S Nazifi, A Khoshvaghti, M Kazemi
doaj  

Deep Jump Learning for Off-Policy Evaluation in Continuous Treatment Settings [PDF]

open access: yesarXiv, 2020
We consider off-policy evaluation (OPE) in continuous treatment settings, such as personalized dose-finding. In OPE, one aims to estimate the mean outcome under a new treatment decision rule using historical data generated by a different decision rule. Most existing works on OPE focus on discrete treatment settings.
arxiv  

Effectiveness and Safety of Apixaban, Dabigatran, and Rivaroxaban Versus Warfarin in Frail Patients With Nonvalvular Atrial Fibrillation

open access: yesJournal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2018
Background Frailty predicts poorer outcomes and decreased anticoagulation use in patients with nonvalvular atrial fibrillation. We sought to assess the effectiveness and safety of apixaban, dabigatran and rivaroxaban versus warfarin in frail nonvalvular ...
B. Martinez   +3 more
semanticscholar   +1 more source

Long‐term outcomes of apixaban as main anticoagulant in patients with HeartMate 3 left ventricular assist devices

open access: yesESC Heart Failure, EarlyView.
Abstract Aims HeartMate 3 (HM3) left ventricular assist devices (LVADs) offer improved haemocompatibility‐related outcomes for end‐stage heart failure patients, facilitating the exploration of alternative anticoagulation therapies beyond warfarin.
Jennifer Jdaidani   +7 more
wiley   +1 more source

Advancements in left ventricular assist devices to prevent pump thrombosis and blood coagulopathy

open access: yesJournal of Anatomy, Volume 242, Issue 1, Page 29-49, January 2023., 2023
Left ventricular assist device (LVAD)‐related blood coagulopathy: Pump thrombosis is one of the most severe adverse events caused by LVADs. The contact of blood with artificial materials of LVAD pumps and cannulas triggers the coagulation cascade. Abstract Mechanical circulatory support (MCS) devices, such as left ventricular assist devices (LVADs) are
Grainne Malone   +12 more
wiley   +1 more source

A Computer-Aided System for Determining the Application Range of a Warfarin Clinical Dosing Algorithm Using Support Vector Machines with a Polynomial Kernel Function [PDF]

open access: yesarXiv, 2019
Determining the optimal initial dose for warfarin is a critically important task. Several factors have an impact on the therapeutic dose for individual patients, such as patients' physical attributes (Age, Height, etc.), medication profile, co-morbidities, and metabolic genotypes (CYP2C9 and VKORC1).
arxiv  

Kernel Assisted Learning for Personalized Dose Finding [PDF]

open access: yesarXiv, 2020
An individualized dose rule recommends a dose level within a continuous safe dose range based on patient level information such as physical conditions, genetic factors and medication histories. Traditionally, personalized dose finding process requires repeating clinical visits of the patient and frequent adjustments of the dosage.
arxiv  

Comparison of warfarin and aspirin for symptomatic intracranial arterial stenosis.

open access: yesNew England Journal of Medicine, 2005
BACKGROUND Atherosclerotic intracranial arterial stenosis is an important cause of stroke. Warfarin is commonly used in preference to aspirin for this disorder, but these therapies have not been compared in a randomized trial.
M. Chimowitz   +12 more
semanticscholar   +1 more source

New oral anticoagulants and their reversal agents [PDF]

open access: yes, 2018
Atrial fibrillation is a commonly encountered pathology in medical practice, and its prevalence has shown a continuous rise over the past years. Atrial fibrillation has a significant impact on patients\u27 quality of life, not only due to the standard ...
Bodean, Oana   +9 more
core   +1 more source

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