Results 151 to 160 of about 145,467 (273)

Diagnostic Performance of Prothrombin Time and Activated Partial Thromboplastin Time in Children: A Service Evaluation

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Coagulation screening, consisting of prothrombin time (PT) and activated partial prothrombin time (aPTT), is routinely performed in paediatrics to identify bleeding disorders or guide peri‐procedural management. We evaluated the trends in utilisation and diagnostic yield of PT and aPTT testing as part of coagulation screening in a ...
Gerard Gurumurthy, Mikias Lemma, Lianna Reynolds, John Grainger, Jecko Thachil   +4 more
wiley   +1 more source

Effects of apixaban compared with warfarin as gain in event-free time – a novel assessment of the results of the ARISTOTLE trial [PDF]

, 2019
Erik Berglund, Lars Wallentin, Jonas Oldgren, Henrik Renlund, John H. Alexander, Christopher B. Granger, Stefan H. Hohnloser, Elaine M. Hylek, Renato D. Lópes, John J.V. McMurray, Per Lytsy   +10 more
openalex   +1 more source

Catheter Ablation Is Associated With a Decrease in Major Adverse Cardiovascular Events and All‐Cause Mortality in Patients With Atrial Fibrillation and Obstructive Sleep Apnea

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Introduction Obstructive sleep apnea (OSA) is a common risk factor for the development and progression of atrial fibrillation (AF). Whether catheter ablation for AF management in patients with coexisting OSA yields survival benefit remains unclear.
Ghassan Bidaoui, Christian Massad, Joe Abi‐Rached, Ahmed Abdelmaksoud, Eman Toraih, Michel Abou‐Khalil, Mayana Bsoul, Montaser Atasi, Amitabh Pandey, Nassir Marrouche, and other members of the TRIAD Team, Yara Menassa, Han Feng, Swati Rao, Chanho Lim, Ala' Assaf, Hadi Younes   +16 more
wiley   +1 more source

Use of Drugs With Actionable Pharmacogenetic Biomarkers and Possible Prescribing Changes Among Older People

Journal of the American Geriatrics Society, EarlyView.
This graphical abstract illustrates the annual prevalence of exposure to CPIC Level A drugs among older adults, categorized by type of pharmacogenetic recommendation. Data are presented per 1000 older individuals (A) and per 1000 prescriptions (B).
Zinan Zhao, Yuxuan Zhao, Xiaowen Hu, Xue Wang, Gengchen Wang, Xinyi Zhang, Wenliang Dong, Luwen Shi, Xiaodong Guan, Christine Y. Lu, Pengfei Jin, Xiaoyan Nie   +11 more
wiley   +1 more source

Correlation between Metabolic Parameters and Warfarin Dose in Patients with Heart Valve Replacement of Different Genotypes

Reviews in Cardiovascular Medicine
Background: Warfarin has become the first choice for anticoagulation in patients who need lifelong anticoagulation due to its clinical efficacy and low price.
Xiaowu Wang, Diancai Zhao, Jipeng Ma, Xia Wang, Jincheng Liu   +4 more
doaj   +1 more source

Prevalence and Duration of Potential Drug–Drug Interactions Among US Nursing Home Residents, 2018–2020

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Nursing home (NH) residents are at increased risk of drug–drug interactions (DDIs) due to multimorbidity and polypharmacy. While prior research suggests that many DDIs lead to adverse drug events in older adults, the extent of exposure to potentially clinically relevant DDIs among United States (US) NH residents is largely unknown ...
Laura A. Reich, Lori A. Daiello, Sarah D. Berry, Adam M. D'Amico, Douglas P. Kiel, Daniel A. Harris, Kaleen N. Hayes, Charles E. Leonard, Yu‐Chia (Sam) Hsu, Andrew R. Zullo   +9 more
wiley   +1 more source

Studies on Regioselective Binding Mode of Steroid Molecules in Homology Modeled Cytochrome P450-2C11 [PDF]

, 2009
In this study, we investigated the regioselective binding mode of steroid molecules and structure requirements for steroid molecules for 16[alpha]-hydroxylation by Cytochrome P450-2C11.
Eiichi Akaho, Hamed I. Ali, Hukihisa Fujita, Morio Yamada   +3 more
core   +1 more source

The Effect of Demographic Factors and VKORC1 1639 G>A Genotypes on Estimated Warfarin Maintenance Dose in Iranian Patients Under Warfarin Therapy [PDF]

, 2018
Fariba Rad, Mohsen Hamidpour, Akbar Dorgalaleh, Behzad Poopak   +3 more
openalex   +1 more source

Development and Implementation of a Medical Cannabis Clinic Within a Geriatrics Primary Care Clinic: Preliminary Data

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Cannabis use is rising among adults, yet few users receive structured medical supervision. Older users face unique risks necessitating specialized oversight. Given their longitudinal relationships and detailed understanding of patients' health and goals, primary care providers are well‐positioned to guide decisions and education ...
Ryan Weaver, Brian Velez, Michael L. Weissberger, Kristin M. Zimmerman   +3 more
wiley   +1 more source

Biochemical and haemostatic variables associated with metastasis in dogs with carcinoma or sarcoma

Journal of Small Animal Practice, EarlyView.
Objectives Identify alterations in biochemical and haemostatic variables between tumour‐bearing dogs with and without metastasis that can be used to predict the presence of metastasis. Materials and Methods Thirty dogs with sarcoma and 29 with carcinoma were included in the analysis.
P. Pazzi, G. T. Fosgate, A. T. Kristensen, A. Goddard   +3 more
wiley   +1 more source