Results 151 to 160 of about 192,309 (409)

Changing the approach to anticoagulant therapy in older patients with multimorbidity using a precision medicine approach [PDF]

open access: yes, 2018
The ageing of the world population has resulted in an increase in the number of older patients with multimorbid conditions receiving multiple therapies.
Capi, Matilde   +8 more
core   +1 more source

Predicting right ventricular failure after left ventricular assist device implant: A novel approach

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Right ventricular (RV) failure (RVF) after left ventricular assist device (LVAD) implant is an important cause of morbidity and mortality. Modern, data‐driven approaches for defining and predicting RVF have been under‐utilized. Methods Two hundred thirty‐two patients were identified with a mean age of 55 years; 40 (17%) were women, 132 ...
Carissa E. Livingston   +6 more
wiley   +1 more source

ОЦЕНКА ТЕРАПЕВТИЧЕСКОЙ ЭФФЕКТИВНОСТИ ВАРФАРИНА ПРОИЗВОДСТВА ЗАО «КАНОНФАРМА ПРАДАКШЕН» (РОССИЯ)

open access: yesАрхивъ внутренней медицины, 2014
Warfarin by «Kanonpharma production» (Russia) and original Warfarin have the similar safety and tolerability. We need some increase of dose of Warfarin by «Kanonpharma production» to reach target rate of INR, then in case of original Warfarin usage.
М. В. Хруслов   +1 more
doaj   +1 more source

Titanocene anticancer complexes and their binding mode of action to human serum albumin: a computational study [PDF]

open access: yes, 2011
Due to the pivotal role played by human serum albumin (HSA) in the transport and cytotoxicity of titanocene complexes, a docking study has been performed on a selected set of titanocene complexes to aid in the current understanding of the potential mode ...
Nutt, David R.   +3 more
core   +1 more source

Comparison of Temporary Interruption of Warfarin Therapy for 3 and 5 days before Surgery in Thailand: A Randomized Controlled Trial

open access: yesSiriraj Medical Journal, 2017
Objective: The ACCP guideline 2008 recommended cessation of warfarin five days before surgery. However, based on the observation of the clinical practice at Siriraj Hospital, we suggested a shorter period of three days before surgery.
Angsu Chartrungsan   +12 more
doaj  

Bootstrap Cross-validation Improves Model Selection in Pharmacometrics [PDF]

open access: yesarXiv, 2019
Cross-validation assesses the predictive ability of a model, allowing one to rank models accordingly. Although the nonparametric bootstrap is almost always used to assess the variability of a parameter, it can be used as the basis for cross-validation if one keeps track of which items were not selected in a given bootstrap iteration.
arxiv  

Risk of Bleeding With 2 Doses of Dabigatran Compared With Warfarin in Older and Younger Patients With Atrial Fibrillation: An Analysis of the Randomized Evaluation of Long-Term Anticoagulant Therapy (RE-LY) Trial

open access: yesCirculation, 2011
Background— Dabigatran 150 and 110 mg twice a day and warfarin are effective for stroke prevention in atrial fibrillation. The purpose of this study was to compare their risks of bleeding in the Randomized Evaluation of Long-Term Anticoagulant Therapy ...
J. Eikelboom   +15 more
semanticscholar   +1 more source

Health Care Savings from Personalizing Medicine Using Genetic Testing: The Case of Warfarin [PDF]

open access: yes
Progress towards realizing a vision of personalized medicine - drugs and drug doses that are safer and more effective because they are chosen based on an individual's genetic makeup - has been slower than once forecast.
Lutter, Randall   +2 more
core   +1 more source

Managing atrial fibrillation in the global community: The European perspective. [PDF]

open access: yes, 2013
Atrial fibrillation is a common, global problem, with great personal, economic and social burdens. As populations age it increases in prevalence and becomes another condition that requires careful chronic management to ensure its effects are minimised ...
Camm, AJ   +3 more
core   +1 more source

Warfarin reversal [PDF]

open access: yesJournal of Clinical Pathology, 2004
Warfarin is the most commonly used oral anticoagulant in the UK. It is associated with few side effects apart from haemorrhage. The most appropriate way to reverse the anticoagulant effect of warfarin depends on the clinical circumstances. In serious bleeding, rapid reversal is required, whereas in minor bleeding or asymptomatic over anticoagulation, a
openaire   +2 more sources

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