Results 211 to 220 of about 94,071 (310)

Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition and Cancer Risk: Insights from a Large Propensity‐Matched Cohort Study

Clinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1547-1554, June 2026.
Proprotein convertase subtilisin/kexin type 9 (PCSK9) monoclonal antibodies (mAbs) lower LDL cholesterol and may influence cancer through immunomodulatory pathways. However, their effect on human cancer incidence remains unknown. We conducted a retrospective, propensity score‐matched study (Clalit Health Services, Israel, 2010–2023) comparing PCSK9 ...
Inbar Nardi Agmon, Chen Gurevitz, Tzippy Shochat, Shiri Kushnir, Guy Witberg, Amos Levi, Dan Gilon, Ran Kornowski, Paaladinesh Thavendiranathan, Husam Abdel Qadir, Zaza Iakobishvili   +10 more
wiley   +1 more source

Treatment Stability of Warfarin and Acenocoumarol in Patients With Mechanical Heart Valves and Atrial Fibrillation: A One-Year Cohort Study. [PDF]

Acta Med Acad
Hajdari Toskić Š, Mević A, Kulo Ćesić A.   +2 more
europepmc   +1 more source

Induction of cytochrome P450 2C9 and P‐glycoprotein activity by antiseizure medications: A systematic review and network meta‐analysis

Epileptic Disorders, Volume 28, Issue 3, Page 855-867, June 2026.
Abstract Objectives Antiseizure medications (ASMs) can induce the activity of drug‐metabolizing enzymes and drug transporters, including cytochrome P450 (CYP)2C9 and P‐glycoprotein (P‐gp). Our objective was to comparatively assess the effects of ASMs on exposure to clinical CYP2C9 and P‐gp substrates.
Hagar Cohen, Nahawand Bahash, Tomer Ben‐Shushan, Ilan Matok, Sara Eyal   +4 more
wiley   +1 more source

Exploring the Nutraceutical Potential of Achillea millefolium L.: Phytochemical Composition, Biological Activities, and Industrial Applications

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Achillea millefolium Linn., commonly known as yarrow, is an extraordinary medicinal plant. A. millefolium has broad therapeutic potential due to its phytochemistry and essential oil composition. It possesses pharmacological properties, including antidiabetic, antioxidant, anti‐inflammatory, liver‐protective, antimicrobial, and gastroprotective effects,
Tooba Majeed, Muhammad Tauseef Sultan, Ahmad Mujtaba Noman, Hassan Raza, Hagar M. Mohamed, Nimra Anees, Muhammad Imran, Muzzamal Hussain, Gamal A. Mohamed, Sabrin R. M. Ibrahim, Entessar Al Jbawi, Ehab M. Mostafa, Samy Selim, Ayman Salama, Mohamed A. Abdelgawad   +14 more
wiley   +1 more source

AI-WAR: a novel warfarin management software with a bidirectional LSTM dosing model improves time in therapeutic range. [PDF]

Front Pharmacol
Li Y, Xu N, Song L, Liu Y, Pei Q, Kuang Y, Yang G.   +6 more
europepmc   +1 more source

When Anticoagulation Leaves its Mark: Aortic Calcification in Long-Term Warfarin Therapy. [PDF]

JACC Case Rep
Ferreira Gomes RA.
europepmc   +1 more source

Risk factors of bleeding in patients with atrial fibrillation undergoing percutaneous coronary intervention: an analysis from the MANJUSRI study. [PDF]

Front Cardiovasc Med
Li Y, Lu W, Wang Y, Chen L, Ma G.
europepmc   +1 more source

Varicocelectomy Restores Spermatogenesis in Fontan‐Associated Varicocele: A Two‐Case Series

IJU Case Reports, Volume 9, Issue 4, July 2026.
ABSTRACT Introduction Fontan circulation may cause chronic venous hypertension and predispose patients to varicocele and infertility, but the clinical significance of surgical treatment remains unclear. Case Presentation We describe two patients with Fontan circulation who developed Fontan‐associated varicocele (FAVC).
Yusuke Tominaga, Tomoko Kobayashi, Yuko Matsumoto, Takatoshi Moriwake, Nariaki Ozaki, Takuya Sadahira, Satoshi Katayama, Shingo Nishimura, Kensuke Bekku, Motoo Araki   +9 more
wiley   +1 more source

Small-molecule inhibition of γ-glutamyl carboxylase reveals a novel anticoagulant strategy. [PDF]

Blood Adv
Shen G, Song D, Li S, Chen X, Richter CE, Dong S, Guo Y, Liu H, Shen Y, Hao Z, Stafford DW, Shavit JA, Cao Q, Tie JK.   +13 more
europepmc   +1 more source

Vascular Calcification: Mechanisms, Models, and Therapies

iNew Medicine, Volume 2, Issue 2, June 2026.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu, Shu Yang, Ziyi Chen, Xiaoxiao Yang, Zhen Liang, Yuanli Chen   +5 more
wiley   +1 more source