Results 61 to 70 of about 192,309 (409)

Estimation of Warfarin Dosage with Reinforcement Learning [PDF]

arXiv, 2021
In this paper, it has attempted to use Reinforcement learning to model the proper dosage of Warfarin for patients.The paper first examines two baselines: a fixed model of 35 mg/week dosages and a linear model that relies on patient data. We implemented a LinUCB bandit that improved performance measured on regret and percent incorrect.
arxiv  

Cardiovascular, Bleeding, and Mortality Risks in Elderly Medicare Patients Treated With Dabigatran or Warfarin for Nonvalvular Atrial Fibrillation

Circulation, 2015
Background— The comparative safety of dabigatran versus warfarin for treatment of nonvalvular atrial fibrillation in general practice settings has not been established.
D. Graham, M. Reichman, M. Wernecke, Rongmei Zhang, M. Southworth, Mark S Levenson, T. Sheu, Katrina Mott, M. Goulding, Monika Houstoun, T. MaCurdy, C. Worrall, J. Kelman   +12 more
semanticscholar   +1 more source

Edoxaban: an update on the new oral direct factor Xa inhibitor. [PDF]

, 2014
Edoxaban is a once-daily oral anticoagulant that rapidly and selectively inhibits factor Xa in a concentration-dependent manner. This review describes the extensive clinical development program of edoxaban, including phase III studies in patients with ...
A. John Camm, AC Skanes, AG Turpie, AJ Camm, AK Kakkar, AT Cohen, B Laulicht, BF Gage, BI Eriksson, BI Eriksson, BI Eriksson, BI Eriksson, BS Stambler, C Kearon, CB Granger, CT Ruff, DE Salazar, G Agnelli, G Agnelli, G Lu, G Raskob, G Raskob, H Masumoto, H Zahir, Henri Bounameaux, J Mendell, J Mendell, J Mendell, J Mendell, J Mendell, J Mendell, J Stampfuss, JH Alexander, JI Weitz, JL Mega, K Ogata, KL Furie, LT Grip, M Crowther, M Hori, M Pirmohamed, MR Lassen, MR Lassen, MR Lassen, MR Lassen, MR Patel, MS Bathala, MU Zafar, N Chung, N Matsushima, R Caterina De, R Caterina De, RP Giugliano, S Kaatz, S Schulman, S Schulman, S Schulman, SE Kimmel, SJ Connolly, SJ Connolly, SJ Connolly, SZ Goldhaber, T Fuji, T Fuji, T Fukuda, T Hulle van der, T Mikkaichi, T Wilke, T Yamashita, TI Verhoef, W Mueck, Y Falck-Ytter, Y Kuroda   +72 more
core   +1 more source

Warfarin therapy and pharmacogenetics: A narrative review of regional and Iraqi studies

Medical Journal of Babylon, 2022
The aim of this work was to review several studies investigating the effects of genetic polymorphisms on warfarin dosing in regional and Iraqi studies and to report any consistent pattern of relevant findings.
Ali Mohammed Abd Alridha, Karrar Mohammed Al-Gburi, Sarah Kadhim Abbood   +2 more
doaj   +1 more source

Three- versus four-factor prothrombin complex concentrate for the reversal of warfarin-induced bleeding [PDF]

, 2018
Objective: The objective of this study was to evaluate the effectiveness of 3-factor prothrombin complex concentrate (3F-PCC) compared to 4-factor PCC (4F-PCC) in warfarin-associated bleeding. Methods: This multicenter, retrospective, cohort study
Abraham, Prasad, Curtis, James, Elder, Tai, Harris, Serena, Holt, Tara, Mcmillian, Wesley, Taylor, Scott   +6 more
core   +1 more source

Influence of sampling on the determination of warfarin and warfarin alcohols in oral fluid. [PDF]

PLoS ONE, 2014
The determination of warfarin, RS/SR- and RR/SS-warfarin alcohols in oral fluid may offer additional information to the INR assay. This study aimed to establish an optimized sampling technique providing the best correlation between the oral fluid and the
Tommaso Lomonaco, Silvia Ghimenti, Isabella Piga, Denise Biagini, Massimo Onor, Roger Fuoco, Fabio Di Francesco   +6 more
doaj   +1 more source

A Case Control Study of Nutrient Intake Deficiencies in Patients Taking Warfarin

Marshall Journal of Medicine, 2015
Introduction We previously published the case of a woman taking warfarin who was found to have scurvy, a disease caused by a deficiency of vitamin C. This led us to hypothesize that patients taking warfarin who consume a diet limited in vitamin K rich
Philip Riley, Kim Lucas Day, George M. Yousef, Sirisha Devabhaktuni, Ashley N. Gaing, Lynne J. Goebel   +5 more
doaj   +1 more source

Effectiveness and safety of reduced dose non-vitamin K antagonist oral anticoagulants and warfarin in patients with atrial fibrillation: propensity weighted nationwide cohort study

British medical journal, 2017
Objective To examine clinical effectiveness and safety of apixaban 2.5 mg, dabigatran 110 mg, and rivaroxaban 15 mg compared with warfarin among patients with atrial fibrillation who had not previously taken an oral anticoagulant.
P. Nielsen, F. Skjøth, M. Søgaard, J. N. Kjældgaard, G. Lip, T. Larsen   +5 more
semanticscholar   +1 more source

GRADE Evidence to Decision (EtD) frameworks : a systematic and transparent approach to making well informed healthcare choices. 2: Clinical practice guidelines [PDF]

, 2016
Funding: Work on this article has been partially funded by the European Commission FP7 Program (grant agreement 258583) as part of the DECIDE project. Sole responsibility lies with the authors; the European Commission is not responsible for any use that ...
the GRADE Working Group
core   +1 more source

Thromboembolic and bleeding events in ICU patients with COVID‐19: A nationwide, observational study

Acta Anaesthesiologica Scandinavica, Volume 67, Issue 1, Page 76-85, January 2023., 2023
Abstract Background Intensive care unit (ICU) patients with Coronavirus disease 2019 (COVID‐19) have an increased risk of thromboembolic complications. We describe the occurrence of thromboembolic and bleeding events in all ICU patients with COVID‐19 in Denmark during the first and second waves of the pandemic.
Lene Russell, Sarah Weihe, Emilie Kabel Madsen, Christine Lodberg Hvas, Jens Wolfgang Leistner, Jens Michelsen, Anne Craveiro Brøchner, Anders Bastiansen, Frederik Mølgaard Nielsen, Nick Meier, Anne Sofie Andreasen, Niels‐Erik Ribergaard, Bodil Steen Rasmussen, Christoffer Grant Sølling, David Levarett Buck, Helle Bundgaard, Helle Scharling Pedersen, Iben Strøm Darfelt, Lone Musaeus Poulsen, Michael Ibsen, Ronni R. Plovsing, Sigurdur T. Sigurdsson, Susanne Iversen, Thomas Hildebrandt, Thomas Mohr, Ulrick Skipper Espelund, Vibeke Jørgensen, Nicolai Haase, Anders Perner   +28 more
wiley   +1 more source