Results 31 to 40 of about 14,168 (156)

An algorithm for managing warfarin resistance

Cleveland Clinic Journal of Medicine, 2009
Some patients need higher-than-expected doses of warfarin (Coumadin) to get their international normalized ratio (INR) into the therapeutic range. The cause of warfarin resistance can be either acquired (eg, poor compliance, drug interactions, dietary interactions) or hereditary, but the genetic mechanisms of warfarin resistance are not well understood.
Olusegun, Osinbowale, Monzr, Al Malki, Andrew, Schade, John R, Bartholomew   +3 more
openaire   +2 more sources

Impact of PCSK9, WDR12, CDKN2A, and CXCL12 Polymorphisms in Jordanian Cardiovascular Patients on Warfarin Responsiveness and Sensitivity

International Journal of General Medicine, 2021
Rasheed K Ibdah,1 Laith N AL-Eitan,2 Nasr N Alrabadi,3 Ayah Y Almasri,2 Adan H Alnaamneh,2 Rame H Khasawneh,4 Mansour A Alghamdi5,6 1Division of Cardiology, Department of Internal Medicine, Faculty of Medicine, Jordan University of Science and Technology,
Ibdah RK, AL-Eitan LN, Alrabadi NN, Almasri AY, Alnaamneh AH, Khasawneh RH, Alghamdi MA   +6 more
doaj  

An Experimental Study to Assess the Ecotoxicity of Warfarin and Tinzaparin on Meiobenthic Amphipods: Original Taxonomic Data from Saudi Arabia and Computational Modeling

Toxics
In the current research, we examined the effects of warfarin (W1 = 5 mg/L and W2 = 25 mg/L) and tinzaparin (T1 = 5 mg/L and T2 = 25 mg/L) on meiofauna using microcosms.
Amal Lassoued, Fehmi Boufahja, Gabriel Plavan, Naoufel Ben Hamadi, Mohamed A. M. Ali, Walid Elfalleh, Riadh Badraoui, Hamdi Bendif, Amor Hedfi   +8 more
doaj   +1 more source

Exacerbation of Hereditary Warfarin Resistance by Azathioprine

Clinical and Applied Thrombosis/Hemostasis, 2010
A 39-year-old Afro-Caribbean man with Crohn disease with recurrent deep vein thromboses and pulmonary emboli was commenced on lifelong warfarin treatment. The patient required high-dose warfarin (>140 mg/wk), which increased further during azathioprine treatment. Cessation of azathioprine resulted in an increase in the international normalized ratio
Pushpakom, Sudeep P., Gambhir, Nikki, Latif, Ayshe, Hadfield, Kristen D., Campbell, Simon, Newman, William G.   +5 more
openaire   +3 more sources

A huge intracardiac thrombus developed in the presence of antithrombin III deficiency in a patient with end-stage renal failure

Türk Kardiyoloji Derneği Arşivi, 2013
In this study, we report a 15-year-old female with end-stage renal disease undergoing hemodialysis, who admitted with acute respiratory failure and generalized edema.
Fatih Köksal Binnetoğlu, Kadir Babaoğlu, Nazan Sarper, Kenan Bek   +3 more
doaj   +1 more source

Warfarin Resisance and Recurrent Thrombosis in an Iranian Patient

Case Reports in Clinical Practice, 2019
Warfarin resisance was known as subtherapeutic INR (International Normalized Ratio) in spite of normally prescribed doses of warfarin. There are few reports of warfarin resisance from Iran.
Masuod Malekzadeh, Marzieh Pazoki
doaj  

The appropriateness of ceftriaxone utilization in government hospitals of Eastern Ethiopia: A retrospective evaluation of clinical practice

SAGE Open Medicine, 2021
Introduction: Drug use evaluation is a method of obtaining information to identify problems related to drug use and if properly developed, a means of correcting the problems. Ceftriaxone is among the most commonly utilized cephalosporins.
Firehiwot Amare, Tigist Gashaw, Mekonnen Sisay, Yohannes Baye, Tewodros Tesfa   +4 more
doaj   +1 more source

Dose-dependent artificial prolongation of prothrombin time by interaction between daptomycin and test reagents in patients receiving warfarin: a prospective in vivo clinical study

Annals of Clinical Microbiology and Antimicrobials, 2017
Background Daptomycin has been reported to cause artificial prolongation of prothrombin time (PT) by interacting with some test reagents of PT. This prolongation was particularly prominent with high concentrations of daptomycin in vitro. However, whether
Makoto Saito, Shuji Hatakeyama, Hideki Hashimoto, Takumitsu Suzuki, Daisuke Jubishi, Makoto Kaneko, Yukio Kume, Takehito Yamamoto, Hiroshi Suzuki, Hiroshi Yotsuyanagi   +9 more
doaj   +1 more source

Bleeding risk in patients prescribed dual antiplatelet therapy and triple therapy after coronary interventions: the ADAPTT retrospective population-based cohort studies

Health Technology Assessment, 2023
Background Bleeding among populations undergoing percutaneous coronary intervention or coronary artery bypass grafting and among conservatively managed patients with acute coronary syndrome exposed to different dual antiplatelet therapy and triple ...
Harris Jessica, Pouwels Koen B, Johnson Thomas, Sterne Jonathan, Pithara Christalla, Mahadevan Kalaivani, Reeves Barney, Benedetto Umberto, Loke Yoon, Lasserson Daniel, Doble Brett, Hopewell-Kelly Noreen, Redwood Sabi, Wordsworth Sarah, Mumford Andrew, Rogers Chris, Pufulete Maria   +16 more
doaj   +1 more source

Assaying of Warfarin in Iranian Warfarin Resistance Patients Blood by HPLC

Pakistan Journal of Biological Sciences, 2008
A simple and rapid HPLC method with UV detecting system has been used in determination of warfarin level in plasma of Iranian patients who received different doses of this drug. Six resistance (10-70 mg day(-1)) and 5 sensitive patients (0.5-2.5 mg day(-1)) were selected for this study. Range of warfarin level in plasma was between 0.93 and 22.8. After
S, Sadrai, P, Ghadam, R, Sharifian, F, Sadeghian   +3 more
openaire   +2 more sources