Results 61 to 70 of about 2,357,394 (215)

An Experimental Study to Assess the Ecotoxicity of Warfarin and Tinzaparin on Meiobenthic Amphipods: Original Taxonomic Data from Saudi Arabia and Computational Modeling

Toxics
In the current research, we examined the effects of warfarin (W1 = 5 mg/L and W2 = 25 mg/L) and tinzaparin (T1 = 5 mg/L and T2 = 25 mg/L) on meiofauna using microcosms.
Amal Lassoued, Fehmi Boufahja, Gabriel Plavan, Naoufel Ben Hamadi, Mohamed A. M. Ali, Walid Elfalleh, Riadh Badraoui, Hamdi Bendif, Amor Hedfi   +8 more
doaj   +1 more source

Cisterna Chyli Dilation Is a Risk Factor for Liver Nodules and Hepatocellular Carcinoma in Fontan‐Associated Liver Disease: Pathophysiological Role of Lymphatic Dysfunction

Hepatology Research, EarlyView.
ABSTRACT Aim In Fontan‐associated liver disease (FALD), chronic congestion often confounds conventional fibrosis markers, complicating surveillance for hepatocellular carcinoma (HCC). Although lymphatic dysfunction is fundamental to Fontan physiology, its contribution to hepatocarcinogenesis remains unclear.
Koji Imoto, Masatake Tanaka, Takeshi Goya, Yuuki Azuma, Tomonobu Hioki, Yusuke Morita, Keisuke Sakaguchi, Nobuhiro Fujita, Takamori Kakino, Ayako Ishikita, Kenichiro Yamamura, Ichiro Sakamoto, Kousei Ishigami, Kohtaro Abe, Yoshihiro Ogawa   +14 more
wiley   +1 more source

A huge intracardiac thrombus developed in the presence of antithrombin III deficiency in a patient with end-stage renal failure

Türk Kardiyoloji Derneği Arşivi, 2013
In this study, we report a 15-year-old female with end-stage renal disease undergoing hemodialysis, who admitted with acute respiratory failure and generalized edema.
Fatih Köksal Binnetoğlu, Kadir Babaoğlu, Nazan Sarper, Kenan Bek   +3 more
doaj   +1 more source

Incretin‐Based Medications in Women and Reproduction: A Systematic Scoping Review and Consensus Guidelines for Clinical Practice

Obesity Reviews, EarlyView.
ABSTRACT Introduction Pregnancy concurrent with incretin‐based medications is contraindicated due to unknown risk of teratogenicity, as is breastfeeding. The aim of this systematic scoping review was to investigate potential risks and benefits of incretin‐based medications in relation to preconception, pregnancy, and postnatal health, and to propose ...
Kate Maslin, Jill Shawe, Sinead Blowers, Michael Ceulemans, Kathryn Hart, Sam Schoenmakers, Amihai Rottenstreich, Heather Hopper, Mojca Jensterle, Angela C. Flynn, Sarah Siegelaar, Annick Bogaerts, Isy Douek, Nicola Heslehurst, Dries Ceulemans, Tricia Tan, Johnathan Pinkney, Martin Whyte, Shahrad Taheri, Roland Devlieger   +19 more
wiley   +1 more source

RELATIVE TOXICITY OF RODENTICIDE COUMATETRALYL AGAINST SOME DOMINANT WILD RAT SPECIES FROM FOUR CITIES IN ASSIUT GOVERNORATE [PDF]

Assiut University Journal of Multidisciplinary Scientific Research, 2019
Rodents are considered as one of the most important pests in Egyptian agriculture. In most countries warfarin and related compounds of anticoagulants are undoubtedly the most commonly used, but resistance to warfarin has increasingly become a big problem.
doaj   +1 more source

Pharmacogenomics in Dentistry: From CYP‐Mediated Drug Response to Precision Prescribing in Oral Healthcare

Oral Diseases, EarlyView.
ABSTRACT Objective This narrative review critically assesses the clinical relevance of pharmacogenomics within dental genomics, distinguishing clinically actionable applications from emerging or investigational findings. Materials and Methods A targeted literature review was conducted in PubMed/MEDLINE, Scopus and Embase for publications from January ...
Giorgia Pieretto, Jessica Cusato, Martina Sansavini, Christian Bacci   +3 more
wiley   +1 more source

Evaluation of warfarin resistance using transcription activator-like effector nucleases-mediated vitamin K epoxide reductase knockout HEK293 cells [PDF]

, 2013
Single nucleotide polymorphisms in the vitamin K epoxide reductase (VKOR) gene have been successfully used for warfarin dosage prediction. However, warfarin resistance studies of naturally occurring VKOR mutants do not correlate with their clinical ...
Jin, D. Y., Tie, K., Tie, J. K., Stafford, D. W.   +3 more
core   +1 more source

Assaying of Warfarin in Iranian Warfarin Resistance Patients Blood by HPLC

Pakistan Journal of Biological Sciences, 2008
A simple and rapid HPLC method with UV detecting system has been used in determination of warfarin level in plasma of Iranian patients who received different doses of this drug. Six resistance (10-70 mg day(-1)) and 5 sensitive patients (0.5-2.5 mg day(-1)) were selected for this study. Range of warfarin level in plasma was between 0.93 and 22.8. After
S, Sadrai, P, Ghadam, R, Sharifian, F, Sadeghian   +3 more
openaire   +2 more sources

Dose-dependent artificial prolongation of prothrombin time by interaction between daptomycin and test reagents in patients receiving warfarin: a prospective in vivo clinical study

Annals of Clinical Microbiology and Antimicrobials, 2017
Background Daptomycin has been reported to cause artificial prolongation of prothrombin time (PT) by interacting with some test reagents of PT. This prolongation was particularly prominent with high concentrations of daptomycin in vitro. However, whether
Makoto Saito, Shuji Hatakeyama, Hideki Hashimoto, Takumitsu Suzuki, Daisuke Jubishi, Makoto Kaneko, Yukio Kume, Takehito Yamamoto, Hiroshi Suzuki, Hiroshi Yotsuyanagi   +9 more
doaj   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, Volume 78, Issue 11, Page 1593-1601, November 2026.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source