Results 131 to 140 of about 5,238,494 (355)

Water metabolism regulating mechanisms in hypokinesia [PDF]

open access: yes
The range of daily fluctuations of the proportion of the amount of consumed water and its content in the body was evaluated by means of a water metabolism regulation factor.
Krotov, V. P.
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Anti-inflammatory Activity of the Water Extract of Sargassum fulvellum [PDF]

open access: bronze, 2012
Da-Hyun Jeong   +7 more
openalex   +1 more source

Pathogenesis of sudden death following water immersion (immersion syndrome) [PDF]

open access: yes
Sympathetic activity under cold stress is investigated. Predominantly vagal cardio-depressive reflexes are discussed besides currently known mechanisms of sudden death after water immersion. Pronounced circulatory centralization in diving animals as well
Buhring, M., Spies, H. F.
core   +1 more source

Governance of a complex system: water [PDF]

open access: yes, 2014
This paper sets out a complex adaptive systems view of water governance. Overview Fresh water is a life - enabling resource as well as the source of spiritual, social and economic wellbeing and development.
Elizabeth Eppel
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Effect of the method of process on the control of microbial growth by water activity in foods [PDF]

open access: yes, 1972
Two methods for preparation of intermediate moisture foods (IMF) were investigated; water absorption and water desorption technique. Results indicate that shelf stability of IMF systems might be enhanced by preparing foods by rehumidifying dehydrated ...
Labuzu, T. D.
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Estrogenic activity, selected plasticizers and potential health risks associated with bottled water in South Africa [PDF]

open access: bronze, 2018
Natalie Aneck-Hahn   +6 more
openalex   +1 more source

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