Results 141 to 150 of about 5,238,494 (355)
A Study on Ajuga bracteosa wall ex. Benth for analgesic activity [PDF]
, 2011 Ethnopharmacological relevance: Ajuga bracteosa wall ex. Benth (Labiatae) is traditionally used medicine in the treatment of malaria and gout. The plant is substitute of cinchona. Its allied species Ajuga Parviflora is also found sporadically.
Akriti Pal , RS Pawar, Int J Cur Bio Med Sci.
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Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
STUDY ON PHYTOCHEMICALS, TOTAL PHENOLS, ANTIOXIDANT, ANTHELMINTIC ACTIVITY OF HOT WATER EXTRACTS OF CORIANDRUM SATIVUM SEEDS [PDF]
, 2017 Manju Madhavan
openalex +1 more source
Enzyme activity in terrestrial soil in relation to exploration of the Martian surface [PDF]
Urease activity in soil is persistent for long periods under low water, low temperature, and sterile regimes, and it was suggested that some form of enzyme-protective mechanism exists in soil.
Ardakani, M. S. +3 more
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Single-cell analysis in hypersaline brines predicts a water-activity limit of microbial anabolic activity. [PDF]
Sci Adv, 2023 Paris ER +11 more
europepmc +1 more source
Activities for Wetland Functions (title provided or enhanced by cataloger) [PDF]
These activities were designed to enhance the third chapter of a module about wetlands that covers flood and erosion control, fish and wildlife habitat, food webs, wetlands "supermarket", and recreation and aesthetics.
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source