Water Governance in Cambodia: From Centralized Water Governance to Farmer Water User Community
Cambodia has abundant water resources in the wet season and a scarcity of water in the dry season. These phenomena undermine the development in this country and pose a threat to long-term development.
Mak Sithirith
doaj +1 more source
Governing carbon mitigation and climate change within local councils: a case study of Adelaide, South Australia [PDF]
There is growing concern about climate change impacts on local government areas. In Australia, the federal carbon tax (from 1 July 2012) will also increase costs for local councils. This paper evaluates what carbon mitigation (i.e.
Zeppel, Heather
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Impact of Three Gorges Project Impoundment on Spatiotemporal Variation of Pollutant Flux in Mainstream Yangtze River [PDF]
[Objective] To investigate the variation patterns of pollutant fluxes in the Yangtze River mainstream before and after the operation of the Three Gorges Project, this study analyzes the annual variations in water quality, runoff, and pollutant fluxes at ...
PENG Lian, ZHAO Min, QIAN Bao, ZHOU Bing-yi
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Decolonising Canadian water governance: lessons from Indigenous case studies. [PDF]
McKibbin C.
europepmc +1 more source
Five challenges to the future of transboundary water governance [PDF]
This repository item contains a single issue of Issues in Brief, a series of policy briefs that began publishing in 2008 by the Boston University Frederick S.
Sullivan, Leeann M.
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Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Caring for Groundwater: How Care Can Expand and Transform Groundwater Governance
Efforts to measure and regulate groundwaters and irrigators are notoriously ineffective. The starting point of this article, therefore, is to question the continued faith in techno-managerial solutions to groundwater depletion.
Margreet Zwarteveen +15 more
doaj +1 more source
Engagement in water governance action situations in the Lake Champlain Basin. [PDF]
Bitterman P, Koliba C.
europepmc +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source

