Results 111 to 120 of about 1,037,697 (313)

Extravascular lung water index, pulmonary vascular permeability index, and global end-diastolic volume index in mechanically ventilated COVID-19 patients requiring prone position ventilation: a preliminary retrospective study. [PDF]

Acute Crit Care, 2022
De Rosa RC, Romanelli A, Gallifuoco M, Messina G, Di Costanzo M, Corcione A.   +5 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Water power chronicle.

, 1913
Title from caption.Title varies slightly, On cover of index of principal articles: Water-power chronicle.Mode of access: Internet.Continued by: Water chronicle, devoted to all water utilization with vol.

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Increased extravascular lung water index (EVLWI) reflects rapid non-cardiogenic oedema and mortality in COVID-19 associated ARDS. [PDF]

Sci Rep, 2021
Rasch S, Schmidle P, Sancak S, Herner A, Huberle C, Schulz D, Mayr U, Schneider J, Spinner CD, Geisler F, Schmid RM, Lahmer T, Huber W.   +12 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Class frequency distribution for a surface raw water quality index in the Vaal Basin

, 2014
A harmonised in-stream water quality guideline was constructed to develop a water quality index for the Upper and Middle Vaal Water Management Areas, in the Vaal basin of South Africa.
Dzwairo, Bloodless, Otieno, Fredrick Alfred O.   +1 more
core  

Remote sensing monitoring of irrigated area in the non-growth season and of water consumption analysis in a large-scale irrigation district

Agricultural Water Management
Globally, water scarcity threatens food security, especially in arid and semi-arid food-producing regions, such as the Hetao Irrigation District (HID), where the water consumption during the non-growth season (spring irrigation, autumn irrigation ...
He Li, Qingfeng Miao, Haibin Shi, Xianyue Li, Shengwei Zhang, Fengxia Zhang, Huailiang Bu, Pei Wang, Lin Yang, Yali Wang, Heng Du, Tong Wang, Weiying Feng   +12 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Ecological water quality index associated with factor analysis to classify surface waters

, 2020
The object of this study was the development of a new water quality index called the Ecological Water Quality Index (EWQI) which is flexible enough to represent the ecological status of surface waters by assessing chemical quality based on supranational ...
Boyacioglu, Hayal, Boyacioglu, Hulya, Boyacıoglu, H.   +2 more
core   +1 more source

Application of Spectral Index-Based Logistic Regression to Detect Inland Water in the Caucasus [PDF]

, 2021
The Caucasus is a diverse region with many climate zones that range from subtropical lowlands to mountainous alpine areas. The Caucasus region also contains irrigated agricultural lands, heavily vegetated wetlands, reservoirs, and canals in various ...
Worden, James
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