Results 121 to 130 of about 9,368,548 (327)
WATER QUALITY INDEX IN AN URBAN WATERSHED [PDF]
International Journal of Sustainable Development and Planning, 2016 Raissa C. Gomes +5 more
openaire +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
, 1993 [Revised].; "January 1993.""The purpose of the water marketing program is to develop adequate water supply storage to meet, as nearly as practicable, present and anticipated municipal and industrial water needs through the purchase of water supply ...
Kansas Water Office.
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Мелиорация и гидротехникаPurpose: to develop an algorithm for monitoring the erosion state of an area using open remote sensing data based on the example of the Volga River water protection zone and to propose a preliminary variant of nature-based bank protection measure ...
Kristina S. Semenova +2 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Ground water pollution potential of Champaign County, Ohio
, 1995 "April, 1995."; Includes bibliographical references (pages 26-31)A ground water pollution potential map of Champaign County has been prepared using the DRASTIC mapping process.
Jones, A. Wayne
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Frontiers in Ecology and EvolutionSeasonal water-level fluctuations associated with hydroelectric reservoir management can generate littoral disturbances, with consequences for the sustainability of Lake Trout (Salvelinus namaycush) populations across North America.
Marie-Joëlle Lauzier +9 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
WATER QUALITY INDEX – AN INSTRUMENT FOR WATER RESOURCES MANAGEMENT [PDF]
Aerul şi Apa: Componente ale Mediului, 2014 Water quality status assessment can be defined as the evaluation of physical, chemical, biological state of the water in relation with the natural state, anthropogenic effects and future uses.
PAIU MĂDĂLINA +1 more
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