Results 121 to 130 of about 2,756,178 (300)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

JUSTIFICATION OF AN ALGORITHM FOR MONITORING WATER PROTECTION ZONE EROSION USING SATELLITE IMAGES AND THE SELECTION OF ANTI-EROSION BANK PROTECTION MEASURES

Мелиорация и гидротехника
Purpose: to develop an algorithm for monitoring the erosion state of an area using open remote sensing data based on the example of the Volga River water protection zone and to propose a preliminary variant of nature-based bank protection measure ...
Kristina S. Semenova, Nartmir V. Khanov, Anastasia A. Kadyseva   +2 more
doaj   +1 more source

Golin river water quality assessment in Kermanshah province using water quality index and river pollution index

سلامت و محیط, 2022
Background and Objective: Increasing the productivity of surface water, the unsustainable development of agriculture in the boundaries of rivers, and human sewage have reduced the quality of these water resources.
Houshang Ghamarnia, Meisam Palash, Zoleikha Palash   +2 more
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

WATER QUALITY INDEX – AN INSTRUMENT FOR WATER RESOURCES MANAGEMENT [PDF]

Aerul şi Apa: Componente ale Mediului, 2014
Water quality status assessment can be defined as the evaluation of physical, chemical, biological state of the water in relation with the natural state, anthropogenic effects and future uses.
PAIU MĂDĂLINA, BREABĂN IULIANA GABRIELA   +1 more
doaj  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

SEASONAL VARIABILITY OF CENTRAL ARCTIC OCEAN SEA-ICE COVER: NEW BIOMARKER (IP25 AND PIP25) DATA FROM SEDIMENT TRAPS DEPLOYED ON SOUTHERN LOMONOSOV RIDGE [PDF]

, 2012
During the Polarstern 1995 Expedition, a long-term mooring system with two cone-shaped multi-sampling traps was deployed at the dominantly ice-covered western slope of the southern Lomonosov Ridge (81°04.5'N, 138°54.0'E, 1712 m water depth). One trap was
Fahl, Kirsten, Stein, Rüdiger
core  

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

A Water Monetary Standard: An Economic Thesis [PDF]

In emerging markets and economies with limited supplies of potable water, the current monetary policy governing water distribution has failed or will eventually fail.
Jackson, Michael
core   +1 more source

Biological and climatic influences on the dace Leuciscus leuciscus in a southern chalk-stream [PDF]

, 1986
The dace, Leuciscus leuciscus (L.) is an important cyprinid in terms of population biomass in chalk streams of southern England. Dace recruitment has been shown to vary widely from year to year and it is thought that this variation is largely as a result
Mann, R.H.K., Mills, C.A.
core