Results 101 to 110 of about 951,237 (293)
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Changes in physiological parameters of boldo plants under water deficit conditions
Pesquisa Agropecuária TropicalWater deficit is one of the main factors affecting the growth and development of boldo plants. This study aimed to evaluate the effects of water deficit on the growth and physiological parameters of Plectranthus barbatus.
Hellen Lilian Matos da Silva +6 more
doaj +1 more source
Factors restricting diffusion of water-soluble spin labels
Biophysical Journal, 1977 Line broadening of spin label signals is treated in terms of concentration, viscosity, charge and temperature dependencies. Line broadening of spin label signals may be caused either by spin label interactions or by the interaction between a spin label and a second paramagnetic species.
Keith, A.D. +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Haematological and serum biochemical responses of chickens to hydric stress
Animal, 2013 Dehydration can be extremely damaging to the performance and welfare of indigenous chickens. The effect of water restriction on haematological and biochemical parameters was compared in Naked Neck (NNK) and Ovambo (OVB) chickens. A total of 54 8-week-old
N. Chikumba, H. Swatson, M. Chimonyo
doaj +1 more source
Osmoregulatory and Antioxidants Modulation by Salicylic Acid and Methionine in Cowpea Plants under the Water Restriction. [PDF]
Plants (Basel), 2023 Oliveira APDS +11 more
europepmc +1 more source
Effect of Restricted Water Consumption on Broiler Chickens
Poultry Science, 1965 Abstract CHICKENS cannot survive very long when deprived of water. A ten percent loss of body water through dehydration and excretion results in serious physical disorders (Romanoff and Romanoff, 1949). Dehydration is particularly noticeable in the shanks, and some mortality may result as reported by Marble and Jeffrey (1955).
S U, KELLERUP, J E, PARKER, G H, ARSCOTT
openaire +2 more sources
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source