Results 51 to 60 of about 304,910 (303)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Regulatory Mechanisms in BiosystemsModern processes of climate change are accompanied by a number of negative factors, which include aridization, desertification, soil degradation and erosion.
V. A. Gorban +4 more
doaj +1 more source
Mitigation of GHGs Emission From Soils by a Catalyzed In-Situ Photo-Oxidative Polymerization of Soil Organic Matter [PDF]
, 2010 Agricultural lands under food and bio-energy crops, managed grass and permanent crops including agro-forestry, occupy about 40-50% of the Earth's land surface^1^. In 2005, agriculture accounted for an estimated emission of 5.1 to 6.1 GtCO2-eq/yr (10-
Alessandro Piccolo, Riccardo Spaccini
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Damage assessment of concrete structures exposed to fire [PDF]
, 2013 During a fire, concrete structures behave in most cases very well. It could therefore be of economic interest to repair the damaged structures, as costs for demolition and rebuilding can be avoided and the building can be reused faster.
Annerel, Emmanuel, Taerwe, Luc
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Guan'gai paishui xuebao, 2021 【Objective and objective】 Soil aggregate is a function unit commonly used to describe the impact of soil structure on soil fertility and quality. It is temporally dynamic, modulated by a myriad of biotic and abiotic factors such as wetting-drying cycles ...
HAN Xiao +3 more
doaj +1 more source
Soil aggregation, water-holding capacity, and biological activity under no-till systems and cropping sequences in the Lao PDR [PDF]
, 2010 In the four southern districts (Kenthao, Paklay, Boten, and Thongmixay) of Xayabury province, the current cropping systems are based on cash crop production.
Boyer, Johnny +10 more
core
Coarse-grained simulation of amphiphilic self-assembly [PDF]
, 2007 We present a computer simulation study of amphiphilic self assembly performed using a computationally efficient single-site model based on Gay-Berne and Lennard-Jones particles. Molecular dynamics simulations of these systems show that free self-assembly
Allen M. P. +5 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source