Results 131 to 140 of about 7,119 (256)

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Identification of Leaf Waxy Candidate Gene and Expression Changes in Related Genes in Response to Cold Stress of Cabbage (<i>Brassica oleracea</i> L.). [PDF]

Curr Issues Mol Biol
Shao D, Ren Y, Deng C, Wen J, Li B, Li Q, Zhang L.   +6 more
europepmc   +1 more source

Lactylation Reprogramming in the Bone Infection Microenvironment Identifies PGK1 K361 as a Potential Therapeutic Target for Osteogenic Dysfunction

Advanced Science, EarlyView.
Staphylococcus aureus (S. aureus) infection creates a high‐lactate microenvironment, promoting p300‐mediated lactylation of PGK1 at lysine 361 (K361). Lactylated PGK1 translocates to the mitochondrial outer membrane and interacts with VDAC3. This interaction triggers FtMt downregulation, iron accumulation, and excessive PINK1/Parkin‐mediated mitophagy,
Han‐jun Qin, Si‐ying He, Ting‐hui Xiao, Da‐mao Dai, Xin‐jia Hu, Nan Jiang   +5 more
wiley   +1 more source

Peroxidase‐Mimicking Nanozymes for Rapid Detection of Infectious Diseases

Advanced Science, EarlyView.
Peroxidase‐mimicking nanozymes (PMNs) have emerged as robust and versatile materials for rapid infectious disease diagnostics. This review highlights the rational design and controlled synthesis of PMNs, summarizes key biomarkers relevant to infectious diseases, examines their integration into diverse rapid detection platforms, and highlights ...
Shikuan Shao, Victor Fernandez‐Gonzalez, Xiaochuan Wang, Blake Pylipow, Claudia Herrera, Xiaohu Xia   +5 more
wiley   +1 more source

Regulatory Mechanisms of Free Umami Amino Acid Accumulation in Fresh Waxy Kernels: Insights from Transcriptome and Metabolomics Analyses. [PDF]

Foods
Zhao L, Huang K, Luo L, Yu X, Shen N, Wu Y, Wu J, Shi J, Yue E.   +8 more
europepmc   +1 more source

Sugar‐Armored Pesticides: Self‐Assembled System for Enhanced Foliar Adhesion and Sustained Delivery of Hydrophobic Antimicrobials Against Bacterial Diseases

Advanced Science, EarlyView.
This study develops a sugar‐armored, self‐assembled pesticide delivery system that enhances foliar adhesion, provides sustained release, effectively disrupts biofilms, and demonstrates superior bactericidal activity for improved disease control.
Jinghan Yang, Juan Liu, Xiaohui Wang, Peiyi Wang   +3 more
wiley   +1 more source

Effects of a novel loss-of-function waxy endosperm allele on sorghum seed development and grain quality. [PDF]

G3 (Bethesda)
Dhiman P, Soumen S, Nigam D, Bean SR, Wu X, Patil GB, Xin Z, Jiao Y.   +7 more
europepmc   +1 more source

EFFECT OF THE WAXY GENE IN MAIZE POLLEN,—A REPLY TO CRITICISMS [PDF]

Genetics, 1926
R A, Brink, J H, Macgillivray, M, Demerec   +2 more
openaire   +2 more sources

AP‐Lab: An AI‐Driven Autonomous Pilot‐Scale Platform Bridging Materials Discovery and Industrial Manufacturing

Advanced Science, EarlyView.
AP‐Lab bridges materials discovery and industrial manufacturing by coupling proprietary datasets with an application benchmark (PCR Ct). A closed‐loop optimization workflow integrates ML, LLM, and autonomous synthesis/testing to refine magnetic nanoparticles–based nucleic‐acid extraction systems.
Zhan‐Long Wang, Zhifen Ma, Wenxing Song, Guolai Jiang, Boshi Jiang, Mingyang Jiang, Weiliang Shu, Bing Wang, Zhiyuan Wan, Shengyong Geng, Zhen Zhao, Wenhua Zhou, Xue‐Feng Yu   +12 more
wiley   +1 more source

Identification of a Leaf Cuticular Wax Biosynthesis Gene <i>BrCER2</i> in Chinese Cabbage (<i>Brassica rapa</i> L. ssp. <i>pekinensis</i>). [PDF]

Plants (Basel)
Huang Y, Bai X, Ying W, Wang Y, Yang C, Huang M, Xu L, Fang H, Wu J, Zang Y.   +9 more
europepmc   +1 more source