Results 131 to 140 of about 2,466,381 (317)

Licensing weak patents [PDF]

open access: yes
In this paper, we revisit the issue of licensing ‘weak' patents under the shadow of litigation. Departing from the seminal paper by Farrell and Shapiro [2008], we consider innovations of any size and not only ‘small' innovations, and we allow the number ...
David Encaoua, Yassine Lefouili
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

On the weak solution of moving boundary problems

open access: yes, 1978
The weak formulation of moving boundary problems with possibly vanishing specific heat, that is governed by parabolic and/or elliptic differential equations, is developed. The uniqueness of the resulting weak solution is then proved.
Crowley, AB
core  

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Characterizing the deformation behavior of weak sandstone from micro-vision

open access: yes, 2012
[[abstract]]This study explores the mechanism associated with the characteristics of the weak sandstone from micro-vision. Firstly, compression tests with tiny specimens are conducted and the photographs of deformation could be obtained simultaneously ...
Weng, M.C.   +3 more
core  

A Femtosecond Electron‐Based Versatile Microscopy for Visualizing Carrier Dynamics in Semiconductors Across Spatiotemporal and Energetic Domains

open access: yesAdvanced Science
Carrier dynamics detection in different dimensions (space, time, and energy) with high resolutions plays a pivotal role in the development of modern semiconductor devices, especially in low‐dimensional, high‐speed, and ultrasensitive devices.
Yaqing Zhang   +9 more
doaj   +1 more source

Repairbads: An automatic and adaptive method to repair bad channels and segments for OPM-MEG

open access: yesNeuroImage
The optically pumped magnetometer (OPM) based magnetoencephalography (MEG) system offers advantages such as flexible layout and wearability. However, the position instability or jitter of OPM sensors can result in bad channels and segments, which ...
Fulong Wang   +8 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Fe‐Based Nanocrystalline Magnetic Shielding Cylinder with Subfemtotesla‐Level Magnetic Noise

open access: yesAdvanced Science
The precision measurement of extremely weak magnetic fields using spin‐exchange relaxation‐free atomic magnetometers demands magnetic shielding system with high shielding efficiency and low magnetic noise.
Peipei Shen   +13 more
doaj   +1 more source

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